FORM 4 


                            U.S. SECURITIES AND EXCHANGE COMMISSION
                               WASHINGTON, D.C. 20549
                   STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Check this box if no longer
subject to Section 16. Form 4    Filed pursuant to Section 16(a) of the
or Form 5 obligations           Securities Act of 1934, Section 
may continue.  SEE    17(a) of the Public Utility Holding Company Act of 1935 
Instruction 1(b).       or Section 30(f) of the Investment Company Act 
                             of 1940


1. Name and Address of Reporting Person 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to Issuer CARUSO, JOHN A. ENZON, INC. (ENZN) (Check all applicable) _______ Director ______ 10% Owner (Last) (First) (Middle) 3. IRS or Social 4. Statement for ___X____ Officer ______ Other Security Number of Month/Year (give title below) 5 FRANKLIN ROAD Reporting Person (specify below) (Voluntary) FEBRUARY 1996 VICE PRESIDENT, BUSINESS DEVELOPMENT GENERAL COUNSEL AND SECRETARY (Street) 5. If Amendment, Date of Original MENDHAM, NEW JERSEY 07945 (Month/Year) (City) (State) (Zip) TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED 1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired 5. Amount of 6. Owner- 7. Nature (Instr. 3) action action (A) or Disposed of Securities ship of In- Date Code (D) Beneficially Form: direct (Month/ (Instr. (Instr. 3, 4 and 5) Owned at (D) or Bene- Day/ 8) End of Indirect ficial Year) Month (I) Owner- (Instr. 3 (Instr. ship and 4) 4) (Instr. 4) Code V Amount (A) or Price (D)
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over) FORM 4 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED (E.G., puts, calls, warrants, options, convertible securities)
1. Title of Derivative 2.Conver-3.Trans-4.Transac-5.Number of6.Date 7.Title and Amount of 8.Price9.Number10. 11. Na- Security sion action tion Deriv- ExercisableUnder-lying of of Owner- ture (Instru. 3) or Date Code ative and Securities (Instr. 3 Deriv-Deriv- ship of In- Exercise(Month/Day/(Instr.SecuritiesExpirationand 4) ative ative Form direct Price Year)8) Ac- Date Secur-Secur- of De- Bene- of quired (A) (Month/Day/ ity ities ficial Deriv- or Disposed Year) (Instr.Bene- rivative Own- ative of (D) 5) ficially Secu- ership Security (Instr. 3, Owned ity: (Instr. 4) 4, and 5) at End (D) or of Indi- Month rect (Instr. (I) 4) (Instr. 4) CodeV (A) (D) Date Expira- Title Amount Exer- tion or cisableDate Number of Shares Employee Stock Option 40,000 ++ 7/17/05Common Stock 40,000 D -- (right to buy)+ $3.50 7/17/95 A V 40,000 $3.50
Explanation of Responses: + Granted under the Company's Non-Qualified Stock Option Plan, as amended, a Rule 16b-3 plan. ++ Exercisable as to 20,000 shares on July 17, 1996 and as to 20,000 shares on July 17, 1997. ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. /S/ JOHN A. CARUSO 02/23/96 SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). **Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, SEE Instruction 6 for procedure. SEC 1474 (8-92) Page 2