Filed Pursuant to Rule 425
Under the Securities Act of 1933
And Deemed Filed Pursuant to Rule 14a-12
Under the Securities Exchange Act of 1934
Subject Company: Enzon Pharmaceuticals, Inc.
NPS Pharmaceuticals, Inc.
Commission File No. 000-12957

The following materials were distributed to employees of Enzon Pharmaceuticals, Inc. (“Enzon”) in connection with the announcement of the proposed business combination between Enzon and NPS Pharmaceuticals, Inc. (“NPS”).