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ENZON PHARMACEUTICALS INC
10-K
--12-31
48292702
505014000
false
0000727510
Yes
No
Accelerated Filer
No
2011
FY
2011-12-31
<p>
<font size="2"><b>(1) Description of Business</b></font>
</p><br/><p align="justify">
<font size="2">          On
January 29, 2010, Enzon Pharmaceuticals, Inc. and
subsidiaries (Enzon or the Company) consummated the sale of
its specialty pharmaceutical business, comprised principally
of the Company’s products and contract manufacturing
segments. These divested components are reflected in these
consolidated financial statements as discontinued operations
and historical information related to the divested components
has been reclassified accordingly. As part of this
transaction, the Company also divested an in-process research
and development asset of the specialty pharmaceutical
business and reported the proceeds in revenue from continuing
operations. Subsequent to the sale of the specialty
pharmaceutical business, the Company committed to performing
certain research and development and general and
administrative services to facilitate transition (see Note
22, Discontinued Operations).</font>
</p><br/><p align="justify">
<font size="2">          Following
the sale of the specialty pharmaceutical business, Enzon is a
biotechnology company dedicated to the research and
development of innovative therapeutics for cancer patients
with high unmet medical needs. The Company incurred workforce
and facilities-related restructuring charges during 2011,
2010 and 2009 which reflected the transition from a fully
integrated biopharmaceutical company with research,
manufacturing and marketing operations to a biotechnology
company dedicated to oncology research and development (see
Note 13, Restructurings).</font>
</p><br/><p align="justify">
<font size="2">          Operations
are funded in part by the receipt of royalty revenues from
licensing arrangements with other companies related to sales
of products developed using the Company’s proprietary
Customized PEGylation Linker Technology (Customized Linker
Technology®) – primarily PEGINTRON, marketed by
Merck & Co., Inc. The Company operates in one business
segment. The Company’s Principal Executive Officer
(chief operating decision maker) reviews the Company’s
operating results on an aggregate basis and manages the
Company’s operations as a single operating unit. As of
December 31, 2011, the Company’s operations and assets
resided exclusively in the United States.</font>
</p><br/><p align="justify">
<font size="2">          The
Company’s pipeline drug development programs utilize two
platforms – Customized Linker Technology and
third-generation messenger ribonucleic acid (mRNA)-targeting
agents utilizing the Locked Nucleic Acid (LNA) technology.
The Company currently has four compounds in clinical
development: PEG-SN38 and the mRNA antagonists targeting
Hypoxia-Inducible Factor-1α (HIF-1α), Survivin and
Androgen Receptor (AR). In addition, the Company has other
novel LNA targets in various stages of preclinical
research.</font>
</p><br/><p align="justify">
<font size="2">          The
Company’s continuing business is subject to significant
risks and uncertainties including, but not limited to:</font>
</p><br/><ul>
<li>
<div align="justify">
<font size="2">The risk that the Company will not achieve
success in its research and development efforts,
including clinical trials conducted by either the Company
or its collaborative partners.</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">The risk that the Company will experience
operating losses for the next several years.</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">The risk that there will be a decline in
sales of products sold by others from which the Company
derives royalty revenues.</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">Decisions by regulatory authorities
regarding whether and when to approve the Company’s
regulatory applications.</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">The risk that the Company will fail to
obtain adequate financing to meet its future capital and
financing needs.</font>
</div>
</li>
<li>
<div>
<font size="2">The risk that key personnel will leave the
Company.</font>
</div>
</li>
</ul><br/>
<p>
<font size="2"><b>(2) Summary of Significant Accounting
Policies</b></font>
</p><br/><p>
<font size="2"><i>Principles of Consolidation</i></font>
</p><br/><p align="justify">
<font size="2">          The
consolidated financial statements include the accounts of the
Company and its wholly owned subsidiaries. All intercompany
balances and transactions have been eliminated as part of the
consolidation. Prior to the sale of the specialty
pharmaceutical business, assets and liabilities of the
Company’s Canadian subsidiary were translated into U.S.
dollar equivalents at rates in effect at the balance sheet
date. Currency translation adjustments were recorded in
stockholders’ equity in accumulated other comprehensive
income (loss). Subsequent to the sale, the net assets
(primarily cash) of the subsidiary were converted into U.S.
dollars at current rates with fluctuations recognized in
earnings.</font>
</p><br/><p align="justify">
<font size="2"><i>Use of Estimates</i></font>
</p><br/><p align="justify">
<font size="2">          The
preparation of consolidated financial statements in
conformity with accounting principles generally accepted in
the U.S. requires management to make estimates and
assumptions that affect reported amounts of assets and
liabilities, disclosures of contingent assets and liabilities
at the date of the financial statements, and the reported
amounts of revenues and expenses during the reporting period.
These estimates include the valuation of investments, legal
and contractual contingencies, stock-based compensation, and
income taxes. Although management bases its estimates on
historical experience and various other assumptions that are
believed to be reasonable under the circumstances, actual
results could differ from these estimates.</font>
</p><br/><p align="justify">
<font size="2"><i>Financial Instruments and Fair
Value</i></font>
</p><br/><p align="justify">
<font size="2">          The
carrying values of cash, cash equivalents, other current
assets, accounts payable and accrued expenses in the
Company’s consolidated balance sheets approximated their
fair values at December 31, 2011 and 2010 due to their
short-term nature. Marketable securities are carried on the
consolidated balance sheets at fair value. Fair values and
carrying amounts of the Company’s financial instruments
at December 31, 2011 are indicated below (in
thousands):</font>
</p><br/><table cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="9%" valign="bottom">
<p>
 
</p>
</td>
<td width="67%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Description</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Fair Value</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Carrying<br />
Amount</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="2">Marketable securities (Note 4)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">218,967</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">218,967</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="2">4% Convertible Notes Payable (Note
6)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">129,825</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">129,499</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p>
<font size="2"><i>Cash Equivalents</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company considers all highly liquid debt instruments
purchased with remaining maturities of three months or less
to be cash equivalents. As of December 31, 2011 and 2010, the
Company held $98.1 million and $386.2 million of cash
equivalents, respectively.</font>
</p><br/><p align="justify">
<font size="2"><i>Marketable Securities</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company classifies its investments in debt and equity
securities as either short-term or long-term based upon their
stated maturities and the Company’s ability and intent
to hold them. Debt securities with stated maturities of one
year or less are classified as current assets. Debt
securities with stated maturities greater than one year are
classified as noncurrent assets when the Company has the
ability and intent to hold them for at least one year.
Investments in debt securities are classified as
available-for-sale. Unrealized gains and losses (which are
deemed to be temporary), net of related tax effect when
appropriate, are included in the determination of other
comprehensive income (loss) and reported in
stockholders’ equity. The cost of debt securities is
adjusted for amortization of premiums and accretion of
discounts to maturity. The amortization and accretion, along
with realized gains and losses, are included in investment
income, net. The cost of securities is based on the specific
identification method.</font>
</p><br/><p align="justify">
<font size="2"><i>Notes Payable</i></font>
</p><br/><p align="justify">
<font size="2">          The
carrying value of the Company’s 4% convertible senior
unsecured notes outstanding at December 31, 2011 and 2010 was
$129.5 million and $134.5 million, respectively, and the fair
value of these notes was $129.8 million and $182.4 million at
December 31, 2011 and 2010, respectively. Fair value of the
Company’s notes payable is based on quoted market
prices.</font>
</p><br/><p align="justify">
<font size="2"><i>Property and Equipment</i></font>
</p><br/><p align="justify">
<font size="2">          Property
and equipment are stated at cost. Depreciation of fixed
assets is provided by the straight-line method over the
estimated useful lives of the assets. When assets are retired
or otherwise disposed of, the cost and related accumulated
depreciation are removed from the accounts, and any resulting
gain or loss is recognized in operations for the period.
Amortization of leasehold improvements is calculated using
the straight-line method over the remaining term of the lease
or the life of the asset, whichever is shorter. The costs of
repairs and maintenance are charged to operations as incurred
while significant improvements are capitalized.</font>
</p><br/><p align="justify">
<font size="2"><i>Deferred Debt Issuance Costs</i></font>
</p><br/><p align="justify">
<font size="2">          Costs
incurred in issuing the Company’s notes payable have
been recorded as deferred debt issuance costs and are
included within the balances of other assets and other
current assets in the accompanying consolidated balance
sheets. Such amounts are being amortized using the
straight-line method, which approximates the effective
interest method, over the terms of the related financing. The
amortization of deferred debt issuance costs is included in
interest expense in the accompanying consolidated statements
of operations. At the time of repurchase or other
extinguishment of notes, a pro rata amount of deferred debt
issuance costs is written off to interest expense. Upon
conversion of notes, a pro rata amount of deferred issuance
costs is written off against additional paid-in
capital.</font>
</p><br/><p align="justify">
<font size="2"><i>Revenue Recognition</i></font>
</p><br/><p align="justify">
<font size="2">          Royalty
revenue from the Company’s agreements with third parties
is recognized when the Company can reasonably determine the
amounts earned. In most cases, this will be upon notification
from the third-party licensee, which is typically during the
quarter following the quarter in which the sales occurred.
The Company does not participate in the selling or marketing
of products for which it receives royalties. No provision for
uncollectible accounts is established upon recognition of
revenues.</font>
</p><br/><p align="justify">
<font size="2">          Contingent
payments due under the asset purchase agreement for the sale
of the specialty pharmaceutical business are recognized as
income when the milestone has been achieved and collection is
assured. Such payments are non-refundable and no further
effort is required on the part of the Company or the other
party to complete the earning process.</font>
</p><br/><p align="justify">
<font size="2">          The
Company does not routinely participate in research and
licensing arrangements that have multiple deliverables. The
sale of the specialty pharmaceutical business, however, did
involve the application of the guidance regarding multiple
deliverables in separating the revenues associated with the
sale of in-process research and development from the other
elements of the transaction, principally the assets sold as
part of discontinued operations and the continuing
involvement of the Company in contract research activities.
The Company determined that the in-process research and
development had value to the buyer of the specialty
pharmaceutical business on a stand-alone basis and that there
was objective and reliable evidence available to support the
allocation of the total purchase price to the respective
units of accounting (see Note 22, Discontinued
Operations).</font>
</p><br/><p>
<font size="2"><i>Research and Development
Expenses</i></font>
</p><br/><p align="justify">
<font size="2">          All
research and development costs are expensed as incurred.
These include the following types of costs incurred in
performing research and development activities: clinical
trials, clinical manufacturing costs, contract services,
salaries, share-based compensation and benefits and
administrative support costs. Non-refundable advance payments
to acquire goods or pay for services that will be consumed or
performed in future periods are capitalized and amortized
over the period of expected benefit. Costs to acquire
in-process research and development projects and technologies
that have no alternative future use at the date of
acquisition are expensed as incurred.</font>
</p><br/><p align="justify">
<font size="2">          Substantial
portions of the Company’s preclinical and clinical trial
work are performed by third-party contract research
organizations (CROs) and other vendors. The Company accrues
expenses for costs for work performed by CROs based upon the
estimated amount of the total effort completed on each study
or project using factors such as the number of patients
enrolled, the number of active clinical sites and the
duration for which the patients will be enrolled in the
study. Similar approaches are taken in estimating the
percentage of completion in relation to contracts with
contract manufacturing organizations. The Company bases the
estimates on the information available at the time and
records actual expenses as work is completed and
invoiced.</font>
</p><br/><p align="justify">
<font size="2"><i>Income Taxes</i></font>
</p><br/><p align="justify">
<font size="2">          Income
taxes are accounted for under the asset and liability method.
Deferred tax assets and liabilities are recognized for the
estimated future tax consequences attributable to differences
between the financial statement carrying amounts of existing
assets and liabilities and their respective tax bases and
operating loss and tax credit carryforwards. Deferred tax
assets and liabilities are measured using enacted tax rates
expected to apply to taxable income in the years in which
those temporary differences are expected to be realized. The
effect of a change in tax rates or laws on deferred tax
assets and liabilities is recognized in operations in the
period that includes the enactment date of the rate change. A
valuation allowance is established to reduce the deferred tax
assets to the amounts that are more likely than not to be
realized from operations.</font>
</p><br/><p align="justify">
<font size="2">          Tax
benefits of uncertain tax positions are recognized only if it
is more likely than not that the Company will be able to
sustain a position taken on an income tax return. The Company
has no liability for uncertain positions. Interest and
penalties, if any, related to unrecognized tax benefits,
would be recognized as income tax expense.</font>
</p><br/><p align="justify">
<font size="2"><i>Concentrations of Risk</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company’s holdings of financial instruments are
comprised principally of money market funds and debt
securities. The Company does not invest in portfolio equity
securities or commodities or use financial derivatives for
trading purposes. The Company seeks reasonable assuredness of
the safety of principal and market liquidity by investing in
rated securities while at the same time seeking to achieve a
reasonable rate of return. The Company’s market risk
exposure consists principally of exposure to changes in
interest rates. The Company’s holdings of debt
securities also are exposed to the risks of changes in the
credit quality of issuers. The Company typically invests the
majority of its investments in the shorter-end of the
maturity spectrum. At December 31, 2011 the portfolio had a
weighted average effective maturity of just over a year and
contained securities readily tradable in a market that
enables flexibility in terms of timing of disposal. Cash
equivalents are primarily held in a number of triple-A rated
institutional money market funds as well as several corporate
and U.S. government-sponsored entities’ debt
securities.</font>
</p><br/><p>
<font size="2"><i>Stock-Based Compensation Plans</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company recognizes the cost of all share-based payment
transactions at fair value. Compensation cost, measured by
the fair value of the equity instruments issued, adjusted for
estimated forfeitures, is recognized in the financial
statements as the respective awards are earned.</font>
</p><br/><p align="justify">
<font size="2">          The
impact that share-based payment awards will have on the
Company’s results of operations is a function of the
number of shares awarded, the trading price of our stock at
date of grant or modification and vesting, including the
likelihood of achieving performance goals. Furthermore, the
application of the Black-Scholes valuation model employs
weighted average assumptions for expected volatility of the
Company’s stock, expected term until exercise of the
options, the risk free interest rate, and dividends, if any
to determine fair value. Expected volatility is based on
historical volatility of the Company’s common stock; the
expected term until exercise represents the weighted average
period of time that options granted are expected to be
outstanding giving consideration to vesting schedules and the
Company’s historical exercise patterns; and the
risk-free interest rate is based on the U.S. Treasury yield
curve in effect at the time of grant for periods
corresponding with the expected life of the option.</font>
</p><br/><p align="justify">
<font size="2"><i>Cash Flow Information</i></font>
</p><br/><p align="justify">
<font size="2">          Cash
payments for interest on the Company’s 4% notes were
approximately $5.4 million, $5.4 million, and $10.2 million
for the years ended December 31, 2011, 2010 and 2009,
respectively. There were $0.2 million, $0.1 million, and $0.2
million of income tax payments made for the years ended
December 31, 2011, 2010 and 2009, respectively.</font>
</p><br/><p align="justify">
<font size="2">          During
the year ended December 31, 2010, the Company had a noncash
conversion of $115.6 million principal amount of the 4% notes
into approximately 13.5 million shares of its common
stock.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(3) New Accounting
Pronouncements</b></font>
</p><br/><p align="justify">
<font size="2">          In
June 2011, the Financial Accounting Standards Board (FASB)
issued Accounting Standards Update (ASU) 2011-05,
<i>Comprehensive Income (Topic 220).</i> Under the amendments
of ASU 2011-05, an entity is required to present the total of
comprehensive income, the components of net income, and the
components of other comprehensive income either in a single
continuous statement of comprehensive income, or in two
separate but consecutive statements. ASU 2011-05 eliminates
the option to present components of other comprehensive
income as part of the statement of changes in
stockholders’ equity. In December 2011, the FASB issued
ASU 2011-12, <i>Comprehensive Income (Topic 220) - Deferral
of the Effective Date for Amendments to the Presentation of
Reclassifications of Items Out of Accumulated Other
Comprehensive Income in ASU 2011-05,</i> which defers the
effective date of the requirement to present line items on
the income statement for reclassification of items out of
accumulated other comprehensive income until the FASB is able
to reconsider that requirement. ASU 2011-05, as amended by
ASU 2011-12, will become effective for the Company’s
2012 annual financial statements and for interim and annual
financial statements thereafter. Other than the change in
financial statement presentation, the adoption of ASU
2011-05, as amended by ASU 2011-12, is not expected to have a
material effect on the Company’s consolidated financial
statements.</font>
</p><br/><p align="justify">
<font size="2">          In
May 2011, the FASB issued ASU No. 2011-04, <i>Fair Value
Measurement (Topic 820) - Amendments to Achieve Common Fair
Value Measurement and Disclosure Requirements in U.S. GAAP
and IFRS</i>, to clarify existing guidance and change wording
to align U.S. GAAP with IFRS 13. The new standards do not
extend the use of fair value, but rather provide guidance on
how fair value should be applied where it is already required
or permitted. A public entity is required to apply the ASU
prospectively for interim and annual periods beginning after
December 15, 2011, and early adoption is not permitted. In
the period of adoption, the Company will be required to
disclose any changes in valuation technique and related
inputs that result from applying the ASU and to quantify the
total effect, if practicable. The Company does not expect the
adoption of the new guidance to have any effect on the
consolidated financial statements.</font>
</p><br/>
<p>
<font size="2"><b>(4) Marketable Securities</b></font>
</p><br/><p align="justify">
<font size="2">          The
amortized cost, gross unrealized holding gains or losses, and
fair value of the Company’s marketable securities by
major security type at December 31, 2011 were as follows (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="47%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="7%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Amortized<br />
Cost</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Gross<br />
Unrealized<br />
Holding Gains</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Gross<br />
Unrealized<br />
Holding Losses</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Fair<br />
Value*</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Corporate bonds</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">130,201</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">175</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(168</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">130,208</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Commercial paper</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">30,979</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(3</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">30,981</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">U.S. government agency</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">26,531</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">30</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(19</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">26,542</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Variable rate demand notes</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">19,295</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">19,295</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Municipal bonds</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,000</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,000</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Non-U.S. government bonds</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,411</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,413</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Certificates of deposit</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,000</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,000</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Other</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,550</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(22</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,528</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">218,967</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">212</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(212</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">218,967</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="4%" valign="top">
<p>
 
</p>
</td>
<td width="96%" valign="top">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="top">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="top">
<p align="justify">
<font size="2">* Included in current marketable
securities of $58,188 and long-term marketable
securities of $160,779 at December 31, 2011.</font>
</p>
</td>
</tr>
</table><br/><p>
<font size="2">          The
amortized cost, gross unrealized holding gains or losses, and
fair value of the Company’s marketable securities by
major security type at December 31, 2010 were as follows (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="47%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="7%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Amortized<br />
Cost</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Gross<br />
Unrealized<br />
Holding Gains</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Gross<br />
Unrealized<br />
Holding Losses</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Fair<br />
Value*</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Corporate bonds</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">52,079</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">738</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">52,817</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">U.S. government agency bonds</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,000</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">4</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,004</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Non-U.S. government bonds</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,553</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">86</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,639</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Other</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,019</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">111</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(26</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,104</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">61,651</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">939</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(26</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">62,564</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="4%" valign="top">
<p>
 
</p>
</td>
<td width="96%" valign="top">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="top">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="top">
<p align="justify">
<font size="2">* Included in current marketable
securities of $31,170 and long-term marketable
securities of $31,394 at December 31, 2010.</font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          All
marketable debt securities are classified as
available-for-sale. Other securities are predominantly mutual
fund shares belonging to participants in the Company’s
Executive Deferred Compensation Plan totaling $2.5 million
fair value as of December 31, 2011 (in current assets) and
$3.1 million fair value as of December 31, 2010 (in long-term
other assets). As of December 31, 2011, there is a current
liability that offsets the aggregate deferred compensation
plan current assets. As of December 31. 2010, the offsetting
liability was included in other liabilities
(long-term).</font>
</p><br/><p align="justify">
<font size="2">          Fair
value is determined from readily available Level 2 vendor
quoted prices utilizing observable inputs based on active
markets. As of December 31, 2011 and 2010, the Company’s
marketable securities are all valued based on Level 2
inputs.</font>
</p><br/><p align="justify">
<font size="2">          Maturities
of marketable debt securities, based on contractual maturity
and excluding securities related to the Company’s
Executive Deferred Compensation Plan, at December 31, 2011
were as follows (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="96%" style="margin-left:4%">
<tr style="FONT-SIZE:1PX">
<td width="70%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Amortized<br />
Cost</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Fair<br />
Value</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Due in one year or less</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">55,616</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">55,660</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Due after one through three years</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">141,506</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">141,485</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Due more than three years*</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">19,295</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">19,295</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">216,417</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">216,440</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="4%" valign="top">
<p>
 
</p>
</td>
<td width="96%" valign="top">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="top">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="top">
<p align="justify">
<font size="2">* Securities maturing over three years
based on contractual maturities are variable rate
demand notes which contain a put feature allowing them
to be put back to the issuer weekly.</font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          During
the years ended December 31, 2011 and 2010, the Company
realized gains from the sale of marketable securities of $0.2
million and $0.6 million, respectively. For 2009, there was
an immaterial loss realized. During the quarter ended
September 30, 2010, the Company recorded an
other-than-temporary impairment loss of $0.9 million related
to an auction rate security of a bankrupt issuer. The Company
still holds this security but no longer expects to recover
any of its cost. The Company will continue to monitor this
instrument for any signs of recovery.</font>
</p><br/><p align="justify">
<font size="2">          Impairment
assessments are made at the individual security level each
reporting period. When the fair value of an investment is
less than its cost at the balance sheet date, a determination
is made as to whether the impairment is other-than-temporary
and, if it is other-than-temporary, an impairment loss is
recognized in earnings equal to the difference between the
investment’s amortized cost and fair value at such date.
As of December 31, 2011, some of the Company’s
investments were in an unrealized loss position. None of the
underlying investments has been in a continuous loss position
longer than twelve months, and no other-than-temporary
impairment is deemed to have occurred. The Company maintains
a short-term liability for the fair value of the investments
in the Executive Deferred Compensation Plan, and any losses
ultimately realized related to these holdings are borne by
the plan participants.</font>
</p><br/>
<p>
<font size="2"><b>(5) Property and Equipment</b></font>
</p><br/><p align="justify">
<font size="2">          Property
and equipment consist of the following (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="93%" style="margin-left:7%">
<tr style="FONT-SIZE:1PX">
<td width="53%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Estimated<br />
Useful Lives</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Leasehold improvements</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">25,532</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">27,034</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2-14 years</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">*</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Equipment</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">30,052</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">30,002</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2-6 years</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Furniture and fixtures and other</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,791</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,824</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">6 years</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">57,375</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">59,860</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Less: Accumulated depreciation</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">40,573</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">38,286</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">16,802</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">21,574</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          *
Shorter of the lease term or lives indicated</font>
</p><br/><p align="justify">
<font size="2">          Depreciation
charged to operations relating to property and equipment
totaled $5.3 million, $5.8 million, and $6.9 million for the
years ended December 31, 2011, 2010 and 2009,
respectively.</font>
</p><br/><p align="justify">
<font size="2">          During
2011, the Company eliminated from its books and records
fully-depreciated leasehold improvements of $1.2 million and
fully-depreciated furniture and fixtures of $1.0 million at
its former Bridgewater, New Jersey headquarters facility in
connection with the lease terminations for the first and
third floors (See Note 13, Restructurings and Note 20,
Leases).</font>
</p><br/>
<p>
<font size="2"><b>(6) Notes Payable</b></font>
</p><br/><p align="justify">
<font size="2">          The
4% notes mature on June 1, 2013 unless earlier redeemed,
repurchased or converted. The 4% notes are senior unsecured
obligations and rank equal to all future senior unsecured
debt of the Company. The 4% notes are convertible at the
option of the holders into the Company’s common stock at
an initial conversion price of $9.55 per share (104.712
shares per $1,000 principal amount). If the closing price of
the Company’s common stock for at least 20 trading days
in the 30-consecutive-trading-day period ending on the date
one day prior to the date of a notice of redemption is
greater than 140 percent of the applicable conversion price
on the date of such notice, the Company, at its option, may
redeem the 4% notes in whole or in part, at a redemption
price in cash equal to 100 percent of the principal amount of
the 4% notes to be redeemed, plus accrued and unpaid
interest, if any, to the redemption date.</font>
</p><br/><p align="justify">
<font size="2">          Upon
occurrence of a fundamental change, as defined in the
indenture governing the 4% notes, holders of the notes may
require the Company to redeem the notes at a price equal to
100 percent of the principal amount plus accrued and unpaid
interest or, in certain cases, to convert the notes at an
increased conversion rate based on the price paid per share
of the Company’s common stock in the five-trading-day
period prior to the transaction constituting the fundamental
change. The January 29, 2010 sale of the Company’s
specialty pharmaceutical business constituted a fundamental
change and triggered a requirement that the Company offer to
purchase all of its 4% notes at face value. Such an offer was
made on February 5, 2010. The offer expired on March 5, 2010
with no notes having been tendered. The fundamental change
also triggered a change in the conversion rate from 104.712
shares per $1,000 principal amount of notes to 116.535 shares
per $1,000 principal amount during the period January 29,
2010 to March 4, 2010. During this period, notes totaling
$115.6 million principal amount were converted into
approximately 13.5 million shares of common stock of the
Company, reducing the outstanding principal balance of the
notes outstanding to $134.5 million. Subsequent to March 4,
2010, the date the enhanced conversion period ended, the
original conversion rate of 104.712 shares per $1,000
principal amount of notes is again in effect.</font>
</p><br/><p align="justify">
<font size="2">          During
the fourth quarter of 2011, the Company repurchased $5.0
million principal amount of its 4% notes at par and wrote-off
approximately $30,000 of deferred debt issuance costs. During
the first quarter of 2009, the Company repurchased $20.5
million principal amount of its 4% notes at a discount to
par, resulting in a gain of approximately $4.5 million, net
of the write-off of $0.3 million of deferred debt issuance
costs. As of December 31, 2011, the balance of unamortized
deferred debt issuance costs is approximately $0.7
million.</font>
</p><br/><p align="justify">
<font size="2">          Interest
on the 4% notes is payable on June 1 and December 1 of each
year. Accrued interest on the 4% notes amounted to $0.4
million as of December 31, 2011 and 2010.</font>
</p><br/>
<p>
<font size="2"><b>(7) Accrued Expenses and Other</b></font>
</p><br/><p align="justify">
<font size="2">          Accrued
expenses and other current liabilities consists of the
following as of December 31, 2011 and 2010 (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="69%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Compensation</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,634</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,725</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Severance benefits</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,843</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,623</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Professional and consulting fees</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">658</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">667</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Insurance and taxes</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">488</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">386</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Interest</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">432</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">448</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Deferred compensation plan
liability</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,533</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Other</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,104</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,346</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">13,692</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">14,195</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/>
<p>
<font size="2"><b>(8) Stockholders’ Equity</b></font>
</p><br/><p>
<font size="2"><i>Preferred Stock</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company has authorized 3,000,000 shares of preferred stock in
one or more series of which 600,000 are designated as Series
B in connection with the Rights Plan.</font>
</p><br/><p>
<font size="2"><i>Common Stock</i></font>
</p><br/><p align="justify">
<font size="2">          As
of December 31, 2011, the Company has reserved shares of its
common stock for the purposes detailed below (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="90%" align="center">
<tr style="FONT-SIZE:1PX">
<td width="88%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Non-Qualified and Incentive Stock
Plans</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">8,930</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Shares issuable upon conversion of 4%
Notes due 2013</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">13,560</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Employee Stock Purchase Plan</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">600</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">23,090</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p>
<font size="2"><i>Share Repurchase Programs</i></font>
</p><br/><p align="justify">
<font size="2">          On
December 21, 2010, the Company announced a share repurchase
program, under which management may use up to $200.0 million
to purchase the Company’s outstanding common shares.
Transactions in the Company’s stock are recorded on a
settlement date basis. Through December 31, 2010, the Company
paid approximately $0.4 million to repurchase and retire
30,000 shares at an average cost of $12.45 per share. Since
the inception of the Company’s repurchase program, the
cumulative number of shares repurchased and retired through
September 30, 2011 amounts to 11,461,449 shares at a total
cost of $121.5 million, or an average cost per share of
approximately $10.60. During the third quarter of 2011, the
Company decided to suspend the repurchase program.</font>
</p><br/><p align="justify">
<font size="2">          On
December 3, 2009, the Company announced a share repurchase
program under which management may use up to $50.0 million to
purchase the Company’s outstanding common shares. During
the fourth quarter of 2010, the Company completed the entire
$50.0 million program, retiring approximately 4.7 million
shares in total at an average cost of $10.63 per share.
Approximately $48.0 million was paid in 2010 to purchase
approximately 4.5 million shares at an average cost of $10.65
per share.</font>
</p><br/><p>
<font size="2"><i>Rights Plan</i></font>
</p><br/><p align="justify">
<font size="2">          Holders
of the Company’s common stock own one preferred stock
purchase right for each share of common stock owned by such
holder. These rights currently entitle holders of our common
stock to purchase one one-thousandth of a share of our Series
B preferred stock for $190.00, except, in certain
circumstances described below, holders may receive common
stock. However, the rights are not immediately exercisable
and will become exercisable only upon the occurrence of
certain events. If a person or group acquires, or announces a
tender or exchange offer that would result in the acquisition
of 15 percent or more of our common stock while the
stockholder rights plan remains in place, then, unless (1)
the rights are redeemed by us for $0.01 per right or (2) the
board of directors determines that a tender or exchange offer
for all of our outstanding common stock is in the best
interest of the Company and the stockholders, the rights will
become exercisable by all rights holders, except the
acquiring person or group, for (i) shares of our common stock
or (ii) in certain circumstances, shares of the third-party
acquirer, each having a value of twice the right’s
then-current exercise price. Pursuant to an amendment to the
rights plan dated July 23, 2009, stockholders may
beneficially own less than 19 percent of the outstanding
shares of common stock of the Company without becoming an
acquiring person and thereby triggering the rights under the
plan. Prior to the amendment, stockholders who reported
beneficial ownership of the common stock of the Company on
Schedule 13G under the Securities Exchange Act of 1934, as
amended, could beneficially own less than 20 percent of the
outstanding shares of common stock of the Company without
becoming an acquiring person, and all other stockholders
could beneficially own less than 15 percent of the
outstanding shares of common stock of the Company without
becoming an acquiring person. The rights expire on May 16,
2012.</font>
</p><br/>
<p>
<font size="2"><b>(9) Sale of In-Process Research and
Development</b></font>
</p><br/><p align="justify">
<font size="2">          When
the Company sold its specialty pharmaceutical business in
January 2010, it retained its research and development
organization. Prior to the sale, the Company’s research
and development function was engaged in, among other things,
studies oriented towards the next-generation formulations of
Oncaspar and Adagen, two products that were among those sold
as part of the specialty pharmaceuticals business. The
in-process research and development related to those two
products was included in the sale. The $40.9 million selling
price was management’s best estimate of its standalone
fair value based on the stage of development and
consideration of future milestone payments. All necessary
technology and knowhow was transferred to the purchaser at
the time of the sale, and the purchaser could resell the
in-process research and development asset. The activities
necessary to complete the work on the Oncaspar and Adagen
next-generation formulations could be performed by the
purchaser or others. No portion of the selling price was
attributed to the transition services agreement referred to
below in Note 22, Discontinued Operations, as that agreement
represents an arm’s-length market rate of return for the
services being provided and those services are completely
separate from the in-process research and development.</font>
</p><br/><p align="justify">
<font size="2">          During
2011, the Company earned a $5.0 million milestone payment
from the purchaser of the specialty pharmaceutical business
resulting from the approval of a supplemental Biologic
License Application (sBLA) for the manufacture of SS
Oncaspar.</font>
</p><br/>
<p>
<font size="2"><b>(10) Contract Research and Development
Revenue and Miscellaneous Income</b></font>
</p><br/><p align="justify">
<font size="2">          Contract
research and development is specific to the transition
services agreement the Company entered into with the
purchaser of the specialty pharmaceutical business. The
transition services agreement was initiated in January 2010
at the time of the sale. It provides for a reimbursement for
services provided by the Company plus a mark-up and totaled
$1.4 million and $9.3 million in 2011 and 2010, respectively.
These services could continue for up to three years after the
sale, but diminished significantly during the course
2011.</font>
</p><br/><p align="justify">
<font size="2">          Miscellaneous
income includes income received pursuant to the transition
services agreement related to general and administrative
support to the purchaser of the specialty pharmaceutical
business and sublease revenues received by the Company from
tenants under terms of sublease agreements. These
transitional services were minimal in 2011 ($0.1 million)
versus 2010 ($2.4 million) as the term of the agreement for
other than research and development support activities was
approximately one year from January 2010. Sublease revenues
of $0.6 million and $0.3 million for 2011 and 2010,
respectively, relate to the Company’s leased facility in
South Plainfield, New Jersey, which commenced in 2009 and
runs through October 2012, and excess leased office space in
Bridgewater, New Jersey, which commenced in 2011 as a result
of the first quarter relocation to Piscataway, New Jersey and
will continue through January 2013 (see Note 20,
Leases).</font>
</p><br/>
<p>
<font size="2"><b>(11) Comprehensive (Loss) Income</b></font>
</p><br/><p align="justify">
<font size="2">          Comprehensive
(loss) income consists primarily of net (loss) income and net
unrealized gain (loss) on marketable securities
available-for-sale and is presented in the consolidated
statements of stockholders’ equity. The following table
reconciles net (loss) income to comprehensive (loss) income
(in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="65%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="7%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Net (loss) income</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(20,763</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">177,243</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">683</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Other comprehensive (loss)
income:</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Unrealized (loss) gain on securities
that<br />
arose during the year*</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(671</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(979</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,236</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Currency translation adjustment*</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(742</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">730</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Reclassification adjustments*:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Impairment loss included in net
loss</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">896</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">(Gain) loss on sale of securities</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(240</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(589</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">11</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Total other comprehensive (loss)
income</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(911</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(1,414</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,977</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Total comprehensive (loss) income</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(21,674</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">175,829</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">4,660</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="2%" valign="top">
<p>
 
</p>
</td>
<td width="98%" valign="top">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="top">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="top">
<p align="justify">
<font size="2">* Information has not been tax-effected
due to the establishment of a full allowance against
any related net deferred tax asset.</font>
</p>
</td>
</tr>
</table><br/>
<p>
<font size="2"><b>(12) Loss Per Common Share</b></font>
</p><br/><p align="justify">
<font size="2">          Basic
loss and earnings per common share is computed by dividing
the loss from continuing operations, income from discontinued
operations, and net loss and income by the weighted average
number of shares of common stock outstanding during the
period. Restricted stock awards and restricted stock units
(collectively, nonvested shares) are not considered to be
outstanding shares until the service or performance vesting
period has been completed.</font>
</p><br/><p align="justify">
<font size="2">          The
diluted loss and earnings per share calculation would
normally involve adjusting both the denominator and numerator
as described here if the effect is dilutive. The denominator
would include both the weighted average number of shares of
common stock outstanding and common stock equivalents.
Dilutive common stock equivalents potentially include stock
options and nonvested shares using the treasury stock method,
shares issuable under the employee stock purchase plan
(ESPP), and the number of shares issuable upon conversion of
the Company’s 4% convertible senior notes payable. In
the case of notes payable, the diluted earnings per share
calculation would be further affected by an add-back of
interest to the numerator under the assumption that the
interest would not have been incurred if the notes were
converted into common stock.</font>
</p><br/><p align="justify">
<font size="2">          In
a period in which a loss from continuing operations is
reported, all computations of diluted per-share amounts for
that period must be made exclusive of potential dilutive
shares and the add-back of interest. Accordingly, for each of
the three years ended December 31, 2011, 2010 and 2009,
diluted loss and earnings per share for discontinued
operations and net loss and income are the same as the
corresponding basic loss and earnings per share.</font>
</p><br/><p align="justify">
<font size="2">          The
following table illustrates the computation of basic and
diluted loss and earnings per share for the years ended
December 31, 2011, 2010 and 2009 (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="62%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2"><u>(Loss) Earnings Per Common Share
– Basic and Diluted:</u></font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Loss from continuing operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(20,763</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,800</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(57,202</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Income and gain from discontinued
operations, net</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">180,043</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">57,885</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Net (loss) income</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(20,763</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">177,243</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">683</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Weighted average common shares
outstanding</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">51,910</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">58,466</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">45,186</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Basic and diluted (loss) earnings per
share:</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Continuing operations</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.40</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.05</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(1.26</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Discontinued operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3.08</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1.28</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Net (loss) income</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.40</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3.03</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.02</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          For
the years ended December 31, 2011, 2010 and 2009, the Company
had potentially dilutive common stock equivalents excluded
from the computation of diluted earnings per share amounting
to 17.4 million, 18.8 million, and 35.4 million shares,
respectively.</font>
</p><br/>
<p>
<font size="2"><b>(13) Restructurings</b></font>
</p><br/><p align="justify">
<font size="2">          The
Company incurred the following charges in connection with its
restructuring programs during the years ended December 31,
2011, 2010 and 2009 (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="62%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Employee separation benefits:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Fourth-quarter 2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,485</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Third-quarter 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,835</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Second-quarter 2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">734</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Fourth-quarter 2010</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(72</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,974</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">First-quarter 2010</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(60</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">9,736</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">First-quarter 2009</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">693</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">4,922</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">12,710</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">693</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Other restructuring costs:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,103</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,316</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Total restructuring charges</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">6,025</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">14,026</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">693</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p>
<font size="2"><i>Employee Separation Benefits</i></font>
</p><br/><p align="justify">
<font size="2">          During
the fourth quarter of 2011, the Company recorded total
restructuring charges in the amount of $1.4 million, of which
$1.1 million related to the departure of the Company’s
Chief Operating Officer for severance payments and benefits
that are payable under the terms of the Amended and Restated
Severance Agreement. Additionally, there were several
research and development positions identified for elimination
resulting in a charge of approximately $0.3 million for
separation benefits. As of December 31, 2011, there was
approximately $1.2 million remaining to be paid in accrued
expenses under current liabilities.</font>
</p><br/><p align="justify">
<font size="2">          During
the third quarter of 2011, the Company announced a plan to
reduce its workforce and operating costs to more closely
align its resources and capital with the Company’s
research and development activities. The reduction in force
will reduce the number of employees by approximately 48
percent, to a total of approximately 47, by June 2012.
Separation payments will be made for up to a year following
the respective separations. In connection with this
restructuring, the Company recorded in the third quarter of
2011 a charge of approximately $2.9 million for separation
benefits. As of December 31, 2011, there was approximately
$2.6 million remaining to be paid, of which approximately
$2.0 is in accrued expenses under current liabilities.</font>
</p><br/><p align="justify">
<font size="2">          During
the second quarter of 2011, the Company recorded a
restructuring charge in the amount of $0.7 million related to
the departure of the Company’s Executive Vice President,
Human Resources & Administration for severance payments
and benefits that are payable under the terms of the
Severance and Release Agreement. As of December 31, 2011,
there was approximately $0.3 million remaining to be paid in
accrued expenses under current liabilities.</font>
</p><br/><p align="justify">
<font size="2">          There
were two restructurings initiated during 2010, both of which
reflected the transition of the Company from a fully
integrated biopharmaceutical company with research,
manufacturing and marketing operations to a biotechnology
company focused primarily on research and development. The
fourth-quarter 2010 restructuring program was part of the
Company’s continued efforts to streamline corporate
administrative operations and affected approximately 33
positions. Affected employees were notified in December 2010
and the majority of the terminations occurred during the
first quarter of 2011. Separation payments will be made for
up to a year following the respective separations. In
connection with this restructuring, the Company recorded in
the fourth quarter of 2010 a charge of approximately $3.0
million for separation benefits. As of December 31, 2011,
there was approximately $0.4 million remaining to be paid in
accrued expenses under current liabilities.</font>
</p><br/><p align="justify">
<font size="2">          During
the first quarter of 2010, the Company recorded restructuring
charges of $9.7 million, of which $6.1 million was for
separation benefits resulting from a workforce reduction
involving 64 employees. These actions related primarily to
the sale of the specialty pharmaceutical business, including
several employees who were previously engaged in activities
related to the divested business but who did not transfer to
the employment of the purchaser. These employees were
provided with separation benefits after certain transition
periods during which they assisted with an orderly transfer
of activities and information to the purchaser. The Company
also reassessed its staffing requirements subsequent to the
sale of the specialty pharmaceutical business in light of the
lessened demands on many of its general and administrative
functions. Additionally, the Company’s former President
and Chief Executive Officer resigned from the Company
effective February 22, 2010, resulting in $3.6 million of
expenses for severance payments and benefits that were
payable per the terms of the individual’s employment
agreement. Payments due pursuant to the termination agreement
were made during the third quarter of 2010.</font>
</p><br/><p align="justify">
<font size="2">          The
following table reflects the 2011 and 2010 restructuring
accrual activity for separation benefits and the resulting
liabilities as of December 31, 2011 and 2010 (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="38%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="6%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="17" valign="bottom">
<p align="center">
<font size="2">Employee Separation Benefits</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="17" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">4Q-11</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">3Q-11</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2Q-11</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">4Q-10</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">1Q-10</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Total</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Balance at December 31, 2009</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2010 restructuring accruals</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,974</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">9,889</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">12,863</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2010 payments made</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(8,837</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(8,837</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2010 adjustments</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(153</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(153</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Balance at December 31, 2010</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,974</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">899</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,873</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2011 payments made</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,544</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(839</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(3,383</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2011 adjustments</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(72</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(60</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(132</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2011 restructuring accruals</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,485</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,872</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">662</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">5,019</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2011 payments made</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(301)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(205)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(350)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(856)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">2011 adjustments</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(37)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(37)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Balance at December 31, 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,184</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,630</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">312</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">358</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">4,484</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p>
<font size="2"><i>Other Restructuring Costs</i></font>
</p><br/><p align="justify">
<font size="2">          During
the third quarter of 2011, the Company recorded a
restructuring charge in the amount of $0.7 million to
terminate an operating lease related to the third and first
floors of the its former Bridgewater, New Jersey headquarters
facility, of which $0.2 million is reflected in accrued
expenses under current liabilities as of December 31, 2011.
Termination payments will be completed during the first
quarter of 2012 (see Note 20, Leases).</font>
</p><br/><p align="justify">
<font size="2">          During
the first quarter of 2011, the Company recorded a
restructuring charge in the amount of $0.4 million related to
the excess of committed lease costs over potential sublease
income for office space in Bridgewater, New Jersey that was
vacated during the quarter when the Company relocated its
corporate headquarters to Piscataway, New Jersey.</font>
</p><br/><p align="justify">
<font size="2">          During
the third quarter of 2010, the Company entered into a
sublease for the second floor of its former Bridgewater, New
Jersey headquarters facility. This space became unused as a
result of the reductions in workforce stemming from earlier
restructuring efforts related to the sale of the specialty
pharmaceutical business. The $0.4 million charge represents
the excess of the Company’s contractual lease commitment
over the amount of cash to be received from the subtenant
over the life of the sublease arrangement.</font>
</p><br/><p align="justify">
<font size="2">          During
the second quarter of 2010, the Company recorded a
restructuring charge in the amount of $0.9 million to write
off certain leasehold improvements and furnishings located at
its former Bridgewater, New Jersey headquarters facility that
were determined to be excess and without future value as a
result of the termination and relocation of several
employees.</font>
</p><br/>
<p>
<font size="2"><b>(14) Stock Options</b></font>
</p><br/><p align="justify">
<font size="2">          Through
the Compensation Committee of the Board of Directors, the
Company administers the 2011 Incentive Stock Plan, which
provides incentive and non-qualified stock option benefits
for employees, officers, directors and independent
contractors providing services to Enzon and its subsidiaries.
The 2011 Incentive Stock Plan was adopted by the Board of
Directors in March 2011 and approved by the stockholders in
May 2011. Prior to this, the Company administered the 2001
Incentive Stock Plan, which was adopted by the Board of
Directors in October 2001 and approved by the stockholders in
December 2001. Options granted to employees generally vest
over four years from date of grant and options granted to
directors vest after one year. The exercise price of the
options granted must be at least 100 percent of the fair
value of the Company’s common stock at the time the
options are granted. Options may be exercised for a period of
up to ten years from the grant date. As of December 31, 2011,
approximately 528,000 shares of common stock were reserved
for issuance pursuant to granted options and awards under the
2011 plan. Approximately 4.5 million shares remain available
for grant. Option grants remain outstanding from previous
awards under the 2001 Incentive Stock Plan and an earlier
1987 Non-Qualified Stock Option Plan; however, there will be
no further grants made pursuant to those plans.</font>
</p><br/><p align="justify">
<font size="2">          In
March 2011, the Board of Directors adopted a new compensation
plan for non-employee directors, effective April 1, 2011.
Under the 2011 Outside Director Compensation Plan, each
non-employee director receives an annual grant of stock
options (Annual Option Grant) on the first trading day of the
calendar year with a Black-Scholes value of $25,000 and an
exercise price equal to the closing price of our common stock
on the date of grant. The Annual Option Grant vests in one
tranche on the first anniversary, provided that the recipient
director remains on the Board, and expires on the tenth
anniversary of the date of grant. In addition, upon the
election of a new non-employee director to the Board, such
newly elected director receives a Welcome Grant of stock
options with a Black-Scholes value of $25,000 and an exercise
price equal to the closing price of our common stock on the
date of grant. The Welcome Grant vests in three equal
tranches on each of the first three anniversaries, provided
that the recipient director remains on the Board, and expires
on the tenth anniversary of the date of grant. Furthermore,
for a non-employee Chairperson of the Board, the value of
options covered by the Annual Option Grant and the Welcome
Grant shall be twice the amounts mentioned above. For a
non-employee Vice-Chairperson of the Board, the value of
options covered by the Annual Option Grant and the Welcome
Grant shall be one and a half times the amounts mentioned
above. Options granted in accordance with the 2011 Outside
Director Compensation Plan will be made under the 2011
Incentive Stock Plan.</font>
</p><br/><p align="justify">
<font size="2">          Prior
to April 1, 2011, under the 2007 Outside Director
Compensation Plan, each non-employee director received an
annual grant of stock options (Annual Option Grant) on the
first trading day of the calendar year with a Black-Scholes
value of $75,000 and an exercise price equal to the closing
price of our common stock on the date of grant. The Annual
Option Grant vested in one tranche on the first anniversary,
provided that the recipient director remained on the Board,
and expired on the tenth anniversary of the date of grant. In
addition, upon the election of a new non-employee director,
such newly elected director received a Welcome Grant of stock
options with a Black-Scholes value of $75,000 and an exercise
price equal to the closing price of our common stock on the
date of grant. The Welcome Grant vested in three equal
tranches on each of the first three anniversaries, provided
that the recipient director remained on the Board, and
expired on the tenth anniversary of the date of grant.
Furthermore, for a non-employee Chairperson of the Board, the
value of options covered by the Annual Option Grant and
Welcome Grant were twice the amounts mentioned above. Options
granted in accordance with the 2007 Outside Director
Compensation Plan were made under the 2001 Incentive Stock
Plan.</font>
</p><br/><p align="justify">
<font size="2">          The
following is a summary of the activity in the Company’s
outstanding Stock Option Plans, which include the 2011
Incentive Stock Plan, the 2001 Incentive Stock Plan, and the
1987 Non-Qualified Stock Option Plan (options in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="54%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Options</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Weighted<br />
Average<br />
Exercise<br />
Price Per<br />
Option</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Weighted<br />
Average<br />
Remaining<br />
Contractual<br />
Term (years)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Aggregate<br />
Intrinsic<br />
Value ($000)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Outstanding at January 1, 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,993</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">13.21</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Granted at exercise prices which equaled
the fair value on the date of grant</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">311</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">9.39</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Exercised</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(674</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">8.09</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Forfeited</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(17</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">12.40</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Expired</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(492</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">24.30</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Outstanding at December 31, 2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,121</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">12.19</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3.45</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,231</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Vested and expected to vest at December
31, 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,060</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">12.27</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3.33</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,127</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="2">Exercisable at December 31, 2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,786</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">12.55</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2.74</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,776</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-LEFT:8.65PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          As
of December 31, 2011, there was $0.6 million of total
unrecognized compensation cost related to unvested options
that the Company expects to recognize over a weighted-average
period of 14 months. The Board of Directors of the Company
elected to accelerate the vesting of certain stock options
granted under the Company’s 2001 Incentive Stock Plan as
of the consummation of the sale of the specialty
pharmaceutical business in January 2010. This acceleration
affected outstanding options held by employees at the vice
president level and below and resulted in an additional
expense of $0.2 million in the first quarter of 2010 and $0.1
million in 2009. The charges primarily represented an
acceleration of expense recognition pursuant to the original
award and, to a lesser extent, an adjustment to recognize the
modification of the award in contemplation of the
sale.</font>
</p><br/><p align="justify">
<font size="2">          The
weighted-average grant-date fair value of options granted
during the years ended December 31, 2011, 2010 and 2009 was
$3.29, $4.42, and $2.45, respectively. The total intrinsic
value of options exercised during the years ended December
31, 2011, 2010 and 2009 was $1.9 million, $11.8 million, and
$26 thousand, respectively. During the year ended December
31, 2011, the grant-date fair value of options that vested
was $1.2 million.</font>
</p><br/><p align="justify">
<font size="2">          In
the years ended December 31, 2011, 2010 and 2009, the Company
recorded stock-based compensation of $0.7 million, $2.2
million, and $3.2 million, respectively, related to stock
options. The Company did not realize a net tax benefit
related to stock-based compensation expense. The
Company’s policy is to use newly issued shares to
satisfy the exercise of stock options.</font>
</p><br/><p align="justify">
<font size="2">          The
breakdown of stock-based compensation expense by major line
caption in the statements of operations is shown below (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="59%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Research and development</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">26</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">377</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">804</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">General and administrative</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">684</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,787</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,394</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">710</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,164</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,198</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          Cash
received from exercises of stock options for the years ended
December 31, 2011, 2010 and 2009, was $5.5 million, $31.8
million, and $0.1 million, respectively.</font>
</p><br/><p align="justify">
<font size="2">          The
weighted average assumptions used in the Black-Scholes
option-pricing model for expected volatility, expected term
until exercise and risk-free interest rate are shown in the
table below. Expected volatility is based on historical
volatility of the Company’s common stock. The expected
term of options is estimated based on the Company’s
historical exercise pattern. The risk-free interest rate is
based on U.S. Treasury yields for securities in effect at the
time of grant with terms approximating the expected term
until exercise of the option. No dividend payments were
factored into the valuations. Forfeiture rates, used for
determining the amount of compensation cost to be recognized
over the service period, are estimated based on stratified
historical data.</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="56%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Year Ended<br />
December 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Year Ended<br />
December 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Year Ended<br />
December 31,<br />
2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Expected volatility</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">42</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">42</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">41</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Expected term (in years)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">4.1</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">5.4</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">5.4</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Risk-free interest rate</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1.5</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2.6</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1.7</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
</tr>
</table><br/>
<p>
<font size="2"><b>(15) Restricted Stock Awards and Restricted
Stock Units (Nonvested Shares)</b></font>
</p><br/><p align="justify">
<font size="2">          The
2011 Incentive Stock Plan and, prior to that, the 2001
Incentive Stock Plan provide for the issuance of restricted
stock awards and restricted stock units (collectively,
nonvested shares) to employees, officers and directors. These
awards are issued by the Company effective as of the grant
date, in the case of restricted stock awards, or upon the
vesting date, in the case of a restricted stock unit. The
recipient pays no cash to receive the shares, other than the
$0.01 par value in some cases. These awards have vesting
periods of three to five years when based solely on service.
Certain awards have performance goals which, if met, result
in accelerated vesting that could be shorter than three
years. If the performance goals are not met, the awards
continue to vest over time. All nonvested shares are valued
at fair value. The market price of the Company’s stock
at grant date is factored by an expected vesting period
forfeiture rate based on stratified historical data related
to the assumed vesting period. This amount is then amortized
over the vesting period on a straight-line basis for those
awards that vest based solely on service. For awards subject
to performance-based accelerated vesting, the Company
monitors progress against performance goals and accelerates
the compensation expense as appropriate.</font>
</p><br/><p align="justify">
<font size="2">          Under
the 2011 Outside Director Compensation Plan, each
non-employee director receives an annual grant of restricted
stock units (Annual Restricted Stock Grant) settled in shares
of common stock on the first trading day after June 30 of
each calendar year with a value of $75,000. The Annual
Restricted Stock Grant vests in three equal tranches on each
of the first three anniversaries of the date of grant,
provided that the recipient director remains on the Board. In
addition, upon the election of a new non-employee director to
the Board, such newly elected director receives a Welcome
Grant of restricted stock units settled in shares of common
stock with a value of $100,000. The Welcome Grant vests in
three equal tranches on each of the first three anniversaries
of the date of grant, provided that the recipient director
remains on the Board. Furthermore, for a non-employee
Chairperson of the Board, the value of restricted stock units
covered by the Annual Restricted Stock Grant and the Welcome
Grant shall be twice the amounts mentioned above. For a
non-employee Vice-Chairperson of the Board, the value of
options covered by the Annual Restricted Stock Grant and the
Welcome Grant shall be one and a half times the amounts
mentioned above. Restricted stock units granted in accordance
with the 2011 Outside Director Compensation Plan will be made
under the 2011 Incentive Stock Plan.</font>
</p><br/><p align="justify">
<font size="2">          Prior
to April 1, 2011, under the 2007 Outside Director
Compensation Plan, each non-employee director received an
annual grant of restricted stock (Annual Restricted Stock
Grant) settled in shares of common stock on the first trading
day after June 30 of each calendar year with a value of
$75,000. The Annual Restricted Stock Grant vested in three
equal tranches on each of the first three anniversaries of
the date of grant, provided that the recipient director
remained on the Board. In addition, upon the election of a
new non-employee director, such newly elected director
received a Welcome Grant of restricted stock with a value of
$75,000. The Welcome Grant vested in three equal tranches on
each of the first three anniversaries of the date of grant,
provided that the recipient director remained on the Board.
Furthermore, for a non-employee Chairperson of the Board, the
value of restricted stock covered by the Annual Restricted
Stock Grant and Welcome Grant were twice the amounts
mentioned above. Restricted stock units granted in accordance
with the 2007 Outside Director Compensation Plan were made
under the 2001 Incentive Stock Plan.</font>
</p><br/><p align="justify">
<font size="2">          A
summary of nonvested shares as of December 31, 2011 and
changes during the year ended December 31, 2011 is provided
below (shares in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="70%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="10%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Number of<br />
Nonvested<br />
Shares</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Weighted<br />
Average<br />
Grant Date<br />
Fair Value<br />
Per Share</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Nonvested at January 1, 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">753</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">10.41</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Granted</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">393</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">9.43</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Vested</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(342</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">10.44</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Forfeited</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(130</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">10.02</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Nonvested at December 31, 2011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">674</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">10.14</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          Of
the total number of nonvested shares granted during the year,
203,000 are performance-based and had a grant date fair value
of $10.53 per share. The total grant-date fair value of
nonvested shares that vested during the year ended December
31, 2011 was $3.6 million.</font>
</p><br/><p align="justify">
<font size="2">          As
of December 31, 2011, there was $4.6 million of total
unrecognized compensation cost related to nonvested shares
that the Company expects to be recognized over a weighted
average period of 24 months, reflective of the blend of
service and performance elements. The weighted average
vesting period could be affected if the remaining performance
goals become probable of being achieved and the related
vesting period is shortened as a result.</font>
</p><br/><p align="justify">
<font size="2">          In
the years ended December 31, 2011, 2010 and 2009, the Company
recorded stock-based compensation expense of $2.4 million,
$4.6 million, and $4.5 million related to nonvested share
awards, which is included in the Company’s net income
for each respective period. Of the 2010 expense, $1.2 million
related to vesting of performance-based awards. The board of
directors of the Company elected to accelerate the vesting of
certain nonvested share awards granted under the
Company’s 2001 Incentive Stock Plan as of the
consummation of the sale of the specialty pharmaceutical
business in January 2010. This acceleration resulted in an
estimated $0.8 million additional expense in the first
quarter of 2010 and $0.5 million in 2009. The charges
primarily represented an acceleration of expense recognition
pursuant to the original award and, to a lesser extent, an
adjustment, in certain cases, to recognize the modification
of the award in contemplation of the sale. The Company’s
policy is to use newly issued shares to satisfy nonvested
share awards. There has been no tax benefit realized to date
related to tax deductions for nonvested shares.</font>
</p><br/><p align="justify">
<font size="2">          The
breakdown of stock-based compensation expense by major line
caption in the statements of operations is shown below (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="59%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Research and development</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,281</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,643</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,223</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">General and administrative</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,082</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,963</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,268</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2,363</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">4,606</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">4,491</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/>
<p>
<font size="2"><b>(16) Employee Stock Purchase
Plan</b></font>
</p><br/><p align="justify">
<font size="2">          The
2007 Employee Stock Purchase Plan (ESPP) permits eligible
employees to purchase common stock through payroll deductions
which may not exceed 15 percent of the employee’s
compensation, as defined, at a price equal to 85 percent of
the fair market value of the shares at the beginning of the
offering period (grant date) or at the end of the offering
period (purchase date), whichever is lower. There are two
six-month offering periods in each plan fiscal year,
beginning April 1 and October 1. The ESPP is intended to
qualify under section 423 of the Internal Revenue Code.
Individual participant purchases within a given calendar year
are limited to $25,000 ($21,250 based on the 15-percent
discount) and no more than 2,500 shares on any single
purchase date. An additional one million shares were reserved
for issuance under the plan. All benefit-eligible employees
of the Company may participate in the ESPP other than those
who own shares or hold options or nonvested shares
representing a combined 5 percent or more of the voting power
of the Company’s outstanding stock. Unless terminated
sooner, the ESPP will terminate on January 25, 2017.</font>
</p><br/><p align="justify">
<font size="2">          The
fair value of shares to be issued under the ESPP is estimated
at the grant date and is comprised of two components: the 15
percent discount to fair value of the shares at grant date
and the value of the option granted to participants pursuant
to which they may purchase shares at the lower of either the
grant date or the purchase date fair value. The option
component is valued using the Black-Scholes option pricing
model.</font>
</p><br/><p align="justify">
<font size="2">          The
initial assumptions used in the valuation for each offering
period, April 1 and October 1, are reflected in the following
table (no dividends were assumed):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="20%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="5" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">October</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">April</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">October</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">April</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">October</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="2">April</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="top">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Expected volatility</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">32.02</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">22.17</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">30.31</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">31.80</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">39.52</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">95.62</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Expected term (in years)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.5</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Risk-free interest rate</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.12</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.20</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.24</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.19</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.19</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.39</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">%</font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          Increases
in individual withholding rates within the offering period
could have the effect of establishing a new measurement date
for that individual’s future contributions. Compensation
expense recognized for the ESPP was approximately $66,000,
$99,000, and $172,000 for the years ended December 31, 2011,
2010 and 2009, respectively. Amounts withheld from
participants are classified as cash from financing activities
in the cash flow statement and as a liability in the balance
sheet until such time as shares are purchased. There were two
stock purchases under the ESPP during the year ended December
31, 2011. Based upon the purchase price established as of
March 31, 2011 and September 30, 2011, 41,346 shares were
allocated under the plan in the year.</font>
</p><br/><p align="justify">
<font size="2">          Cash
received from ESPP for the years ended December 31, 2011,
2010 and 2009 was $0.3 million, $0.4 million, and $0.5
million, respectively.</font>
</p><br/><p align="justify">
<font size="2">          The
breakdown of stock-based compensation expense by major line
caption in the statement of operations is shown below (in
thousands).</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="59%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Research and development</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">36</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">67</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">43</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">General and administrative</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">30</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">32</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">129</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">66</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">99</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">172</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/>
<p>
<font size="2"><b>(17) Income Taxes</b></font>
</p><br/><p align="justify">
<font size="2">          The
components of the income tax provision related to continuing
operations are summarized as follows (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="59%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Current:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Federal</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(140</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,195</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">State and foreign</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">205</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(197</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">110</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Total current</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">205</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(337</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,085</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Deferred: Federal and State</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Income tax provision (benefit)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">205</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(337</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,085</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          The
following table represents a reconciliation between the
reported income taxes and the income taxes that would be
computed by applying the federal statutory rate (35%) to
income from continuing operations before taxes (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="59%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<p align="center">
<font size="2">Year Ended December 31,</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="8" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2009</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Income tax benefit computed at federal
statutory rate</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(7,195</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(1,098</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(20,750</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Nondeductible expenses</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">205</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,348</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">699</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Add (deduct) effect of:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Federal research and development tax
credits</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(1,339</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(2,662</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(1,625</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Tax on earnings of foreign
subsidiary</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">174</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">826</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">State income taxes, net of federal
tax</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">20</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(199</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">71</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Effect of change in federal law</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(140</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(2,195</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Increase in beginning of period
valuation allowance</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">8,340</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">588</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">21,715</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Income tax provision (benefit)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">205</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(337</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(2,085</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          Income
tax expense in 2011 was primarily comprised of Canadian
withholding tax. No federal income tax expense was incurred
in relation to normal operating results due either to current
period operating losses or the utilization of deferred tax
assets to offset taxes that would otherwise accrue to
operating income.</font>
</p><br/><p align="justify">
<font size="2">          Federal
legislation, the American Recovery and Reinvestment Act of
2009, which allowed the Company to make an election to treat
certain unused research and alternative minimum tax credit
carryforwards as refundable in lieu of claiming bonus and
accelerated depreciation for “eligible qualified
property” placed in service through the end of 2009 was
extended to 2010. This provided the Company with a $0.1
million benefit in 2010. The balance of the 2010 income tax
benefit reflects a reduction of $0.2 million to state taxes
payable.</font>
</p><br/><p align="justify">
<font size="2">          In
November 2009, federal legislation was enacted under which
the Company was able to carry back its 2009 alternative
minimum tax net operating losses to the five previous years
to offset the alternative minimum taxes that were not
available for carryback prior to the new legislation. The
Company recorded the impact of the carryback, estimated to be
approximately $1.7 million, in the fourth quarter of 2009 and
received a federal income tax cash refund in the first
quarter of 2010. Other legislation in 2009 allowed the
Company to make an election to treat certain unused research
and alternative minimum tax credit carryforwards as
refundable in lieu of claiming bonus and accelerated
depreciation for “eligible qualified property”
placed in service through the end of 2008. This provided the
Company with a $0.5 million benefit in 2009. The balance of
the 2009 income tax expense reflects $0.1 million adjustment
to state taxes payable.</font>
</p><br/><p align="justify">
<font size="2">          The
gain on the sale of the specialty pharmaceutical business,
although taxable, did not result in a federal income tax
liability due to the tax basis the Company had in the
divested assets and the net operating loss generated in 2010.
The utilization of related deferred tax assets associated
with the sale and corresponding reversal of valuation
allowances is reflected in the table that follows.</font>
</p><br/><p align="justify">
<font size="2">          As
of December 31, 2011 and 2010, the tax effects of temporary
differences that give rise to the deferred tax assets and
deferred tax liabilities are as follows (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="72%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="3%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="9%" valign="bottom">
<p align="center">
 
</p>
</td>
<td width="1%" valign="bottom">
<p align="center">
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Deferred tax assets:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Federal and state net operating loss
carryforwards</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">61,213</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">55,510</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Research and development credits
carryforward</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">27,647</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">26,353</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Acquired in-process research and
development</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">7,512</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">8,411</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Capital loss carryforwards</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,165</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,165</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Share-based compensation</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,554</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">719</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Federal alternative minimum tax
credits</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,530</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,530</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Accrued compensation</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,035</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,214</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Other</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,153</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">3,395</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Total gross deferred tax assets</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">107,809</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">100,296</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Less valuation allowance</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(107,365</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(97,587</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">444</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">2,709</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Deferred tax liabilities:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Book basis in excess of tax basis of
acquired assets</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(443</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(1,510</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Undistributed earnings of foreign
subsidiary</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(826</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Unrealized gain on investment
securities</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(1</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(373</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(444</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(2,709</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Net deferred tax assets</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          During
the year ended December 31, 2010, the Company determined that
it would no longer permanently reinvest any of the earnings
of its foreign subsidiaries. As a result, the Company
recorded a net deferred income tax liability of $0.8 million,
with an offsetting valuation allowance, on approximately $2.4
million of accumulated earnings of its foreign subsidiaries.
During the year ended December 31, 2011, the Company
repatriated its earnings from its foreign subsidiaries due to
the closure of the operations. As a result, the Company
reduced the net deferred income tax liability of $0.8 million
and eliminated the offsetting valuation allowance.</font>
</p><br/><p align="justify">
<font size="2">          A
valuation allowance is provided when it is more likely than
not that some portion or all of the deferred tax assets will
not be realized. At December 31, 2011, the Company had
federal net operating loss carryforwards of approximately
$150.3 million that expire in the years 2020 through 2031 and
New Jersey state net operating loss carryforwards of
approximately $95.6 million that expire in the years 2012
through 2018. The Company also has federal research and
development tax credit carryforwards of approximately $20.8
million for tax reporting purposes that expire in the years
2017 through 2031. In addition, the Company has $6.9 million
of state research and development tax credit carryforwards
that expire in the years 2015 through 2026. The
Company’s ability to use the net operating loss and
research and development tax credit carryforwards is subject
to certain limitations due to ownership changes, as defined
by rules pursuant to Section 382 of the Internal Revenue Code
of 1986, as amended.</font>
</p><br/><p align="justify">
<font size="2">          As
of December 31, 2011, management believes that it is more
likely than not that the net deferred tax assets will not be
realized, based on assumptions regarding future operations,
consideration of tax strategies and the reversal of deferred
tax liabilities. As of December 31, 2011 and 2010, the
Company had deferred tax assets of $107.8 million and $100.3
million, respectively. The Company has maintained a valuation
allowance of $107.4 million and $97.6 million at December 31,
2011 and 2010, respectively.</font>
</p><br/><p align="justify">
<font size="2">          The
Company files income tax returns in the U.S. federal
jurisdiction, various state jurisdictions and Canada. The
Company is currently not under examination by the U.S.
Internal Revenue Service, however, the tax years 2008 through
2011 remain open to examination. State income tax returns for
the states of New Jersey and Indiana are generally subject to
examination for a period of 3-4 years after filing of the
respective returns. These state income tax returns are not
currently under examination. Income tax returns for Canada
are generally subject to examination for a period of 3-5
years after filing of the respective return. The
Company’s income tax returns are currently not under
examination by Revenue Canada.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(18) Significant Agreements</b></font>
</p><br/><p align="justify">
<font size="2"><i>Sigma-Tau Group</i></font>
</p><br/><p align="justify">
<font size="2">          The
Company sold its specialty pharmaceutical business to Klee
Pharmaceuticals Inc. (now known as Sigma-Tau PharmaSource,
Inc.), Defiante Farmacêutica, S.A and sigma-tau
Finanziaria S.p.A. (collectively, the sigma-tau Group) in
January 2010. In addition to the initial sale of assets which
has been reflected in the Company’s financial statements
for the year ended December 31, 2010, there were certain
potential future payments to Enzon that were contingent upon
the achievement of stated milestones. During the first
quarter of 2011, the Company earned a $5.0 million milestone
payment resulting from the approval of a supplemental
Biologic License Application (sBLA) for the manufacture of SS
Oncaspar. Remaining potential milestone payments as of
December 31, 2011 were estimated to be $17.0 million. In
addition, there are royalties potentially due to Enzon of 5
to 10 percent on incremental net sales through 2014 by the
sigma-tau Group above a 2009 baseline amount from the four
marketed specialty pharmaceutical products Enzon sold to
them. Approximately $0.5 million and $0.6 million of royalty
revenue were recognized in 2011 and 2010, respectively,
pursuant to this provision of the sale agreement. There can
be no assurance that any of the remaining milestone payments
or any future royalty revenues beyond that which has been
recognized to date will accrue to the benefit of the
Company.</font>
</p><br/><p align="justify">
<font size="2">          Also,
the Company entered into a transition services agreement with
sigma-tau Group whereby Enzon would perform product-support
research and development for up to three years and provide
various general and administrative functions for up to one
year following the closing of the transaction. In
consideration for this work, Enzon is being compensated based
upon costs incurred plus a mark-up defined in the transition
services agreement.</font>
</p><br/><p align="justify">
<font size="2"><i>Santaris Pharma A/S License
Agreement</i></font>
</p><br/><p align="justify">
<font size="2">          In
July 2006, the Company entered into a license agreement with
Santaris Pharma A/S (Santaris) pursuant to which the Company
obtained exclusive rights worldwide, other than in Europe, to
develop and commercialize RNA antagonists directed against
the HIF-1α and Survivin mRNA, as well as RNA antagonists
directed against six additional gene targets selected by the
Company. Since inception of the agreement, initial
acquisition of in-process research and development and
milestone payments have been made totaling $34.0 million,
including milestone payments of $0.0 million, $7.0 million,
and $3.0 million in 2011, 2010, and 2009, respectively,
included in research and development expense in the
accompanying statements of operations. The Company could pay
an additional $142.0 million in milestone payments upon the
successful completion of certain development and regulatory
milestones. If the Company fails to make the requisite
milestone payment for any particular target, Santaris has the
right to recover that target for its own purposes. Santaris
also is eligible to receive single-digit percentage royalties
from any future product sales from products based on the
licensed antagonists. Santaris retains the right to develop
and commercialize products developed under the agreement in
Europe. The royalty term expires on a country-by-country and
product-by-product basis when the last valid LNA platform
patent or LNA compound patent expires not to exceed 21 years
with respect to any product.</font>
</p><br/><p align="justify">
<font size="2"><i>Merck Agreement</i></font>
</p><br/><p align="justify">
<font size="2">          As
a result of a November 1990 agreement, the Company’s
PEGylation technology was used to develop an improved version
of the product INTRON A, PEGINTRON. Merck is responsible for
marketing and manufacturing PEGINTRON on an exclusive
worldwide basis and the Company receives royalties on
worldwide sales of PEGINTRON for all indications. The Company
has no involvement in the selling or marketing of PEGINTRON.
Merck’s obligation to pay the Company royalties on sales
of PEGINTRON terminates, on a country-by-country basis, upon
the later of the date on which the last patent to contain a
claim covering PEGINTRON expires in the country or 15 years
after the first commercial sale of PEGINTRON in such country.
Currently, expirations are expected to occur in 2016 in the
U.S., 2018 in Europe and 2019 in Japan. The royalty
percentage to which the Company is entitled will be lower in
any country where a PEGylated alpha-interferon product is
being marketed by a third party in competition with PEGINTRON
where such third party is not Hoffmann-La Roche. Either party
may terminate the agreement upon a material breach of the
agreement by the other party that is not cured within 60 days
of written notice from the non-breaching party or upon
declaration of bankruptcy by the other party. During the
quarter ended September 30, 2007, the Company sold a
25-percent interest in future royalties payable to it by
Merck on net sales of PEGINTRON occurring after June 30,
2007.</font>
</p><br/><p align="justify">
<font size="2"><i>Nektar Agreement</i></font>
</p><br/><p align="justify">
<font size="2">          In
January 2002, the Company entered into a PEGylation
technology licensing agreement with Nektar under which the
Company granted Nektar the right to grant sub-licenses for a
portion of its patents related to its PEGylation technology
to third-parties. Nektar had the right to sub-license
Enzon’s patents that were defined in the January 2002
agreement and the Company will receive a royalty or a share
of Nektar’s profits for any products that utilize the
Company’s patented PEGylation technology. The
Company’s receipt of royalties related to Nektar
licenses will end in 2014. Effective in January 2007,
Nektar’s right to grant additional sublicenses was
limited to a certain class of our PEGylation technology.
Existing sublicenses granted by Nektar prior to January 2007
were unaffected.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(19) Commitments and Contingent
Liabilities</b></font>
</p><br/><p align="justify">
<font size="2">          The
Company has employment and separation agreements with certain
members of its management that provide for severance payments
and payments following a termination of employment occurring
for various reasons, including a change in control of the
Company.</font>
</p><br/><p align="justify">
<font size="2">          The
Company has been involved in various claims and legal actions
arising in the ordinary course of business. In the opinion of
management, the ultimate disposition of these matters will
not have a material effect on the Company’s consolidated
financial position, results of operations, or
liquidity.</font>
</p><br/><p align="justify">
<font size="2">          The
Company has non-cancelable lease obligations for certain
office and production facilities that have been vacated and
sublet. During the third quarter of 2011, the Company
terminated the lease for the third floor of the former
Bridgewater, New Jersey headquarters facility. During the
fourth quarter of 2011, the Company terminated the lease for
the first floor of the same facility.</font>
</p><br/>
<p>
<font size="2"><b>(20) Leases</b></font>
</p><br/><p align="justify">
<font size="2">          The
Company has several leases for office, warehouse, production
and research facilities and equipment. The non-cancelable
lease terms for the operating leases expire at various dates
between 2012 and 2021 and each agreement includes renewal
options.</font>
</p><br/><p align="justify">
<font size="2">          Future
minimum lease payments, for non-cancelable operating leases
with initial or remaining lease terms in excess of one year
as of December 31, 2011 are as follows (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="15%" valign="bottom">
<p>
 
</p>
</td>
<td width="70%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom" nowrap="nowrap">
<p>
<font size="2">Year ending December 31,</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">Operating<br />
Leases</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr style="background-color: #E5FFFF;">
<td colspan="2" valign="bottom">
<p>
<font size="2">2012</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">1,408</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="2">2013</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">753</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr style="background-color: #E5FFFF;">
<td colspan="2" valign="bottom">
<p>
<font size="2">2014</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">703</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="2">2015</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">703</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr style="background-color: #E5FFFF;">
<td colspan="2" valign="bottom">
<p>
<font size="2">2016</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">703</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="2">Thereafter</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,514</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr style="background-color: #E5FFFF;">
<td colspan="2" valign="bottom">
<p>
<font size="2">Total minimum lease payments</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">7,784</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td colspan="2" valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          Minimum
payments indicated above have not been reduced by future
minimum rentals to be received under noncancelable subleases
of approximately $0.2 million to be received in equal monthly
installments through October 2012 nor approximately $0.4
million to be received in equal monthly installments through
January 2013.</font>
</p><br/><p align="justify">
<font size="2">          Rent
expense amounted to $1.6 million, $2.6 million, and $2.4
million for the years ended December 31, 2011, 2010 and 2009,
respectively. Total rent expense, inclusive of scheduled
increases and rent holidays, is recognized on a straight-line
basis over the term of the lease.</font>
</p><br/><p align="justify">
<font size="2">          The
Company’s use of leased office space at its former
Bridgewater, New Jersey headquarters facility ended during
the first quarter of 2011. As previously discussed, the
Company terminated the third and first floor portions of the
leased space during the third and fourth quarters of 2011,
respectively. The second floor portion of the leased space
has been sublet at a rate lower than the Company’s
committed costs for that space. The lease related to this
portion of the total leased facilities expires on January 31,
2013. The Company remains as the primary lessee with
remaining rental payments, in the aggregate, amounting to
$0.6 million and extending until January 31, 2013. No other
costs related to termination of the lease or restoration of
the facilities are anticipated.</font>
</p><br/><p align="justify">
<font size="2">          The
Company’s use of the leased South Plainfield production
facility has ended. While the Company continues to be
obligated under the original lease for the facility, a
sublease was entered into in January 2010 on favorable terms
such that no liability needs to be accrued. The Company may
incur charges associated with the lease or its termination
prior to or upon the contractual expiration of the lease in
October 2012; however, such exposure, if any, cannot be
estimated at this time.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(21) Retirement Plans</b></font>
</p><br/><p align="justify">
<font size="2">          The
Company maintains a defined contribution 401(k) pension plan
for substantially all of its full-time and part-time
employees, as defined. The Company currently matches 50
percent of the employee’s contribution of up to 6
percent of compensation, as defined. The total Company
contributions for the years ended December 31, 2011, 2010,
and 2009, were $0.4 million, $0.7 million, and $1.0 million,
respectively.</font>
</p><br/><p align="justify">
<font size="2">          In
September 2011, the Board of Directors authorized and
directed the Compensation Committee to terminate the
Company’s Executive Deferred Compensation Plan. As
required by Section 409A of the Internal Revenue Code,
participants in the Plan will receive a payout of their
accounts no earlier than 12 months after the termination of
the Plan and no later than 24 months after such date. At
December 31, 2011, $2.5 million of deferred compensation was
included in other current liabilities. At December 31, 2010,
$3.1 million of deferred compensation was included in other
long-term liabilities. See Note 4, Marketable Securities
relating to the investment of participants’
assets.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(22) Discontinued Operations</b></font>
</p><br/><p align="justify">
<font size="2">          
On January 29, 2010, the Company consummated the sale to the
Sigma-Tau Group of the specialty pharmaceutical business,
comprised principally of the Company’s Products and
Contract Manufacturing segments, in addition to certain
in-process research and development. The Products and
Contract Manufacturing segments constituted components of
Enzon and qualified for treatment as discontinued operations
upon consummation of the transaction. In-process research and
development, which comprised part of the total transaction,
did not constitute a component of Enzon and, accordingly, was
treated as an asset sale and not as discontinued
operations.</font>
</p><br/><p align="justify">
<font size="2"><i>Terms of Sale</i></font>
</p><br/><p align="justify">
<font size="2">          The
asset purchase agreement for the sale of the specialty
pharmaceutical business contained the following major
provisions. Updated status regarding each element is also
provided.</font>
</p><br/><ul>
<li>
<p align="justify">
<font size="2"><i>Cash purchase price was $300.0 million,
subject to certain customary working capital
adjustments</i>.</font>
</p>
</li>
</ul><br/><p align="justify">
<font size="2">          The
cash proceeds received, including the second-quarter 2010
working capital adjustment, amounted to approximately $308.0
million. Transaction costs amounted to approximately $5.0
million reducing net proceeds to approximately $303.0
million. Of this amount, $40.9 million was allocated to the
sale of in-process research and development (see Note 9
above). The net proceeds then attributable to discontinued
operations amounted to $262.6 million and this amount less
the book basis in the respective assets and liabilities (see
below) yielded the gain from discontinued operations of
$176.4 million.</font>
</p><br/><ul>
<li>
<p align="justify">
<font size="2"><i>Up to $27.0 million based on certain
success milestones.</i></font>
</p>
</li>
</ul><br/><p align="justify">
<font size="2">          
During January 2011, the Company received notice that one of
the milestones – the approval of an sBLA regarding a new
API starting material for the manufacture of SS Oncaspar -
was reached, resulting in Enzon being entitled to receive and
recognize $5.0 million of milestone income in 2011. During
the latter half of 2010, circumstances emerged making it
unlikely that another of the milestones related to an
expedited approval process in Europe would be achieved. This
would have resulted in a $5.0 million payment to Enzon. Of
the remaining $17.0 million of potential milestone payments,
it is very unlikely that any will be received in 2012 and
there can be no assurance that the Company will receive any
such payments in the future.</font>
</p><br/><p align="justify">
<font size="2">          The
receipt of milestone payments does not constitute continuing
cash flows of the divested business. These payments are not
contingent upon Enzon performing the research or development
activity. Enzon would be entitled to receive the payments if
the buyer utilized another research and development
provider.</font>
</p><br/><ul>
<li>
<p align="justify">
<font size="2"><i>Royalties of 5 to 10 percent on
incremental net sales above a 2009 baseline amount from
what had been Enzon’s four marketed specialty
pharmaceutical products through 2014</i>.</font>
</p>
</li>
</ul><br/><p align="justify">
<font size="2">          Sales
of the four products during 2011 and 2010 outside the U.S.
were sufficiently in excess of 2009 baseline amounts to
enable Enzon to earn and recognize a nominal amount of
royalty revenue related to this agreement. There can be no
assurance that the Company will receive any additional
royalty payments pursuant to this agreement.</font>
</p><br/><p align="justify">
<font size="2">          These
royalties do not constitute a migration or continuation by
Enzon of the activities that generate the payments. Enzon is
no longer engaged in any manufacturing or marketing
activities. Consequently, these cash flows are deemed to be
indirect in nature.</font>
</p><br/><ul>
<li>
<p align="justify">
<font size="2"><i>Transition services agreement - Enzon
has performed product-support research and development
and has provided various general and administrative
functions for the purchasing parties during 2010 and
2011. In consideration for this work, Enzon is being
compensated based upon costs incurred plus a mark-up
defined in the transition services agreement.</i></font>
</p>
</li>
</ul><br/><p align="justify">
<font size="2">          Revenues
from and associated costs related to research and development
transition services are reflected in the statements of
operations as contract research and development and research
and development – specialty and contracted services,
respectively. Transition services revenues related to general
and administrative efforts are reported in miscellaneous
income and the associated costs are shown as general and
administrative – contracted services. As of December 31,
2011, the Company’s involvement in general and
administrative support efforts has essentially been
concluded. Some diminishing level of research and development
support will continue into 2012.</font>
</p><br/><p align="justify">
<font size="2">          The
cash flows related to the transition services being provided
to the buyer in connection with research and development
activities represent a continuation of Enzon’s corporate
research function. However, the cost-plus arrangement did not
generate sufficient net cash flows during 2011 to be
considered significant. These cash flows will be
substantially lower in 2012. The services are performed at
the request of the sigma-tau Group as a convenience to them.
The services could have been performed by others.</font>
</p><br/><p align="justify">
<font size="2"><i>Discontinued Operations Accounting
Treatment</i></font>
</p><br/><p align="justify">
<font size="2">          While
the sale of the specialty pharmaceutical business was
initiated in November 2009, the assets were not considered to
be held for sale as of December 31, 2009 due to the fact that
the transaction was subject to shareholder approval. Such
approval was obtained at a special meeting of shareholders on
January 27, 2010. As a result, discontinued operations
treatment began in the first quarter of 2010 for the Products
and Contract Manufacturing segments whereby results of
discontinued operations and net assets and liabilities are
reported separately in the statements of operations and cash
flows. The sale of in-process research and development
associated with marketed products was treated as an asset
sale and was not part of discontinued operations for
accounting purposes due to the Company’s significant
continuing involvement in research and development related to
marketed products subsequent to the sale.</font>
</p><br/><ul style="MARGIN-LEFT:6%">
<li style="list-style: none">
<p align="justify" style="MARGIN-LEFT:-13PX">
<font size="2"><u>Assets and liabilities acquired by the
Purchasing Parties include:</u></font>
</p>
</li>
<li>
<div align="justify">
<font size="2">ownership of the four marketed products,
Oncaspar, Adagen, Abelcet and DepoCyt and all related
rights;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">real estate, personal property and
equipment of the business used in the manufacture of
products and performance of the contract manufacturing
operations, including the manufacturing facility in
Indianapolis;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">working capital, including accounts
receivable, inventories, accounts payable and other
prepaids and accruals;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">patents, trademarks, copyrights and other
intangible properties related to the products and
product-specific assets;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">in-process research and development
related to the sourcing of Oncaspar and Adagen;
and</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">other assets and liabilities as specified
in the asset purchase agreement.</font>
</div>
</li>
</ul><br/><ul style="MARGIN-LEFT:6%">
<li style="list-style: none">
<div align="justify" style="MARGIN-LEFT:-13PX">
<font size="2"><u>Assets and liabilities excluded from
the sale of the specialty pharmaceutical business
include:</u></font>
</div>
</li>
<li>
<div align="justify">
<font size="2">cash and cash equivalents;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">tax refunds and tax attributes related to
assets, liabilities and past operations;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">royalties business with the exception of
one contract related to Oncaspar;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">PEG-SN38 and Enzon’s LNA compounds
and PEG technology platform;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">4% convertible senior notes due
2013;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">stock compensation arrangements;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">product claims, product return claims,
environmental and tax liabilities arising prior to the
closing date in excess of any reserves;</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">lease related to South Plainfield, New
Jersey facility; and</font>
</div>
</li>
<li>
<div align="justify">
<font size="2">other assets and liabilities as specified
in the asset purchase agreement.</font>
</div>
</li>
</ul><br/><p align="justify">
<font size="2">          
Summary results of operations of the specialty pharmaceutical
business through January 29, 2010 and for the year ended
December 31, 2009 were as follows (in thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="80%">
<tr style="FONT-SIZE:1PX">
<td width="65%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="14%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">January 1, 2010<br />
through<br />
January 29, 2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2009</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Revenues</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">8,720</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">133,213</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Income before income tax</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3,620</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">57,661</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Income tax benefit (provision)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">224</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Gain on sale of discontinued operations,
net of income tax, as adjusted</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">176,423</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Income and gain from discontinued
operations, net of income tax, as adjusted</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">180,043</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">57,885</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2">          The
sale was a taxable transaction for federal income tax
purposes. The Company did not, however, incur significant tax
liabilities as a result of the transaction due to the tax
basis it has in the disposed of assets and the current year
net operating loss. The potential receipt of milestone and/or
royalty payments will also be taxable events, but the tax
consequences of these payments cannot be estimated at this
time.</font>
</p><br/><p align="justify">
<font size="2">          The
carrying amounts of major classes of assets and liabilities
of the specialty pharmaceutical business were as follows (in
thousands):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="70%">
<tr style="FONT-SIZE:1PX">
<td width="86%" valign="bottom">
<p>
 
</p>
</td>
<td width="3%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="11%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">January 29,</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">2010</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Trade accounts receivable, net</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">11,886</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Inventories</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">19,516</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Other current assets</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">693</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Current assets of discontinued
operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">32,095</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Property and equipment, net</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">12,621</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Amortizable intangible assets,
net</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">48,896</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Non-current assets of discontinued
operations</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">61,517</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Trade accounts payable</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">700</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Accrued expenses</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">5,763</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Liabilities of discontinued
operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">6,463</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<hr size="3" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
</table><br/>
<p align="justify">
<font size="2"><b>(23) Quarterly Results of Operations
(Unaudited)</b></font>
</p><br/><p align="justify">
<font size="2">          The
following tables present summarized unaudited quarterly
financial data (in thousands, except per-share
amounts):</font>
</p><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="44%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="5%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="11" valign="bottom">
<p align="center">
<font size="2">Three Months Ended</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="11" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">March 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">June 30,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">September 30,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2011</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Total revenues <sup>(1)</sup></font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">18,022</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">9,599</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">10,440</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">10,011</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Income (loss) from continuing
operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">431</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(7,068</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(9,105</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(5,021</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Net income (loss)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">431</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(7,068</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(9,105</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(5,021</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Per-share information:</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Income (loss) from continuing
operations:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Basic and diluted</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.01</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.13</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.19</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.10</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Net income (loss):</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Basic and diluted</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.01</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.13</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.19</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.10</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
</table><br/><table border="0" cellspacing="0" cellpadding="0" width="100%">
<tr style="FONT-SIZE:1PX">
<td width="44%" valign="bottom">
<p>
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="2%" valign="bottom">
<p>
 
</p>
</td>
<td width="1%" valign="bottom">
<p>
 
</p>
</td>
<td width="8%" valign="bottom">
<p align="right">
 
</p>
</td>
<td width="5%" valign="bottom">
<p>
 
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="11" valign="bottom">
<p align="center">
<font size="2">Three Months Ended</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="11" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">March 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">June 30,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">September 30,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<p align="center">
<font size="2">December 31,<br />
2010</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p align="center">
<font size="1"> </font>
</p>
</td>
<td colspan="2" valign="bottom">
<hr size="1" width="100%" noshade="noshade" />
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Total revenues <sup>(1)</sup></font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">58,253</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">13,766</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">13,328</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">12,518</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Income (loss) from continuing
operations</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">20,754</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(5,571</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(8,354</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(9,629</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Income and gain from discontinued
operations</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">179,053</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(51</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">—</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">1,041</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2"><sup>(3)</sup></font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="2">Net income (loss)<sup>(2)</sup></font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">199,807</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(5,622</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(8,354</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(8,588</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)<sup>(3)(4)</sup></font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">Per-share information:</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Income (loss) from continuing
operations:</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Basic</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">0.40</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.09</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.16</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Diluted</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">0.29</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.09</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.16</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:17.3PT;TEXT-INDENT:-8.65PT">
<font size="2">Net income (loss):</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
</tr>
<tr>
<td valign="bottom">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Basic</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">3.82</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.09</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
<tr>
<td valign="bottom" style="background-color: #E5FFFF;">
<p style="MARGIN-RIGHT:0IN;MARGIN-LEFT:25.9PT;TEXT-INDENT:-8.65PT">
<font size="2">Diluted</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">2.70</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="1"> </font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.09</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">$</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p align="right">
<font size="2">(0.14</font>
</p>
</td>
<td valign="bottom" style="background-color: #E5FFFF;">
<p>
<font size="2">)</font>
</p>
</td>
</tr>
</table><br/><p align="justify">
<font size="2"><sup>(1)</sup> Revenues are primarily
royalties received on the sale of products by other companies
utilizing Enzon’s Customized Linker Technology. First
quarter 2011 and 2010 revenues include $5.0 million and $40.9
million, respectively, related to the sale of in-process
research and development. Revenues from services in 2011 and
2010 are not material. Subsequent to the January 2010 sale of
the specialty pharmaceutical business (reflected as
discontinued operations), the Company is no longer involved
in the manufacture and sale of products.</font>
</p><br/><p align="justify">
<font size="2"><sup>(2)</sup> As previously reported through
September 30, 2010.</font>
</p><br/><p align="justify">
<font size="2"><sup>(3)</sup> The gain on the sale of the
specialty pharmaceutical business was adjusted during the
fourth quarter 2010 by $1.0 million to reflect the write-off
of accumulated currency translation gains related to the
Canadian subsidiary. This changed the previously reported
income and gain from discontinued operations to $180.0
million or $3.08 per share versus the $179.0 million or $3.06
per share previously reported. Because the sale of
substantially all of the net assets of the Canadian
subsidiary constituted a substantial liquidation for
accounting purposes, the accumulated currency translation
adjustment should have been reported in earnings as part of
the gain calculation during the first quarter of 2010. The
fourth quarter correcting entry was not material to the first
or fourth quarters nor to the full year 2010 results of
operations.</font>
</p><br/><p align="justify">
<font size="2"><sup>(4)</sup> Included in the fourth-quarter
2010 results is a correction of the accounting for the
first-quarter 2010 conversion of a portion of the
Company’s 4% notes. The net effect of the forgone
interest and the write-off of a pro rata amount of deferred
debt issuance costs amounted to $0.8 million and was charged
to earnings during the first quarter of 2010 at the time of
the notes conversion. The correcting adjustment was to credit
interest expense for the $0.8 million and to charge
additional paid-in capital reflective of the capital nature
of the transaction. The noncash correcting entry was not
material to the first or fourth quarters nor to the full year
2010 results of operations. See Note 6, Notes Payable.</font>
</p><br/><p align="justify">
<font size="2">          In
the fourth quarter of 2010, the Company recognized a federal
government Qualifying Therapeutic Discovery Project grant in
the amount of $1.2 million and royalty revenues in the amount
of approximately $0.6 million related to 2010 sales of
divested products in excess of baseline 2009 levels. Also in
the fourth quarter of 2010, the Company recognized a $3.0
million restructuring charge related to a workforce reduction
affecting 33 employees. See Notes 10, Contract Research and
Development Revenue and Miscellaneous Income; 13,
Restructuring and 22, Discontinued Operations.</font>
</p><br/><p align="justify">
<font size="2">          During
the fourth quarter of 2010, the Company determined that it
would no longer permanently reinvest any of the earnings of
its foreign subsidiaries. As a result, the Company recorded a
net deferred income tax liability of $0.8 million on
approximately $2.4 million of accumulated earnings of its
foreign subsidiaries with an offsetting valuation allowance.
See Note 17, Income Taxes.</font>
</p><br/>
<p align="justify">
<font size="2"><b>(24) Subsequent Events</b></font>
</p><br/><p align="justify">
<font size="2">          In
January 2012, the Company repurchased $3.75 million principal
amount of its 4% notes above par and recorded approximately
$0.1 million loss on early retirement of debt.</font>
</p><br/>