SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM 10-Q


                QUARTERLY REPORT UNDER SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


For Quarter Ended December 31, 1996                 Commission File No. 0-12957
                  -----------------                                     -------


                                   ENZON, INC.
             (Exact name of registrant as specified in its charter)



               Delaware                                      22-2372868
(State or other jurisdiction of                             (IRS Employer
 incorporation or organization)                            Identification No.)

20 Kingsbridge Road, Piscataway, New Jersey              08854
(Address of principal executive offices)              (Zip Code)

                                 (908) 980-4500
              (Registrant's telephone number, including area code:)



Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.


Yes   X    No


The number of shares of common stock, $.01 par value, outstanding as of February
3, 1997 was 29,215,451 shares.





PART I FINANCIAL INFORMATION
Item 1. Financial Statements

                           ENZON, INC AND SUBSIDIARIES
                     CONSOLIDATED CONDENSED BALANCE SHEETS
                       December 31, 1996 and June 30, 1996

December 31, June 30, ASSETS 1996 1996 ------------------------------------------------------------- (unaudited) * Current assets: Cash and cash equivalents $10,351,505 $12,666,050 Accounts receivable 3,376,915 2,123,691 Inventories 820,441 985,378 Other current assets 336,923 434,318 ------------- ------------- Total current assets 14,885,784 16,209,437 ------------ ------------ Property and equipment 16,220,391 15,640,823 Less accumulated depreciation and amortization 12,404,047 11,617,690 ------------ ------------ 3,816,344 4,023,133 ------------- ------------- Other assets: Investments 78,293 78,293 Other assets, net 198,970 55,945 Patents, net 1,519,808 1,597,048 ------------ ------------ 1,797,071 1,731,286 ------------ ------------ Total assets $20,499,199 $21,963,856 =========== ============ LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Accounts payable $2,907,511 $2,078,924 Accrued expenses 3,871,054 4,387,052 ----------- ------------ Total current liabilities 6,778,565 6,465,976 ------------ ------------- Accrued rent 933,331 980,908 Royalty advance - RPR 1,171,989 1,600,786 Other liabilities 445 1,728 --------------- -------------- 2,105,765 2,583,422 ------------ ------------ Commitments and contingencies Stockholders' equity: Preferred stock-$.01 par value, authorized 3,000,000 shares: issued and outstanding 144,740 shares at December 31, 1996 and 169,000 shares at June 30, 1996 (liquidation aggregating $6,299,000 at December 31, 1996 and $8,725,000 at June 30, 1996) 1,447 1,690 Common stock-$.01 par value, authorized 40,000,000 shares; issued and outstanding 29,010,003 shares at December 31, 1996 and 27,706,396 shares at June 30, 1996 290,100 277,064 Additional paid-in capital 121,389,101 121,272,024 Accumulated deficit (110,065,779) (108,636,320) ------------- ------------- Total stockholders' equity 11,614,869 12,914,458 ------------ ------------- Total liabilities and stockholders' equity $20,499,199 $21,963,856 ============ ============
*Condensed from audited financial statements. The accompanying notes are an integral part of these unaudited consolidated condensed financial statements. - 2 - ENZON, INC. CONSOLIDATED CONDENSED STATEMENTS OF OPERATIONS Three Months and Six Months Ended December 31, 1996 and 1995 (Unaudited)
Three months ended Six months ended December 31, December 31, December 31, December 31, 1996 1995 1996 1995 ------------------------------------------------------------------------------- Revenues Sales $3,553,975 $2,541,976 $6,274,566 $5,351,024 Contract revenue 5,010 788,236 1,099,309 904,736 -------------- ------------ ---------- ----------- Total revenues 3,558,985 3,330,212 7,373,875 6,255,760 ------------ ------------ ---------- ----------- Costs and expenses Cost of sales 994,325 1,223,876 1,980,314 2,188,577 Research and development expenses 1,980,063 2,390,822 4,409,834 5,081,470 Selling, general and administrative expenses 1,453,545 1,404,350 2,729,612 2,676,320 ---------- ---------- ---------- ---------- Total costs and expenses 4,427,933 5,019,048 9,119,760 9,946,367 ---------- ---------- ---------- ---------- Operating loss (868,948) (1,688,836) (1,745,885) (3,690,607) ----------- ------------ ------------ ------------ Other income (expense) Interest and dividend income 162,770 81,734 319,911 184,079 Interest expense (4,847) (4,263) (11,600) (10,952) Other 180 1,318,379 8,115 1,321,322 ------------ ---------- ------------ ---------- 158,103 1,395,850 316,426 1,494,449 ---------- ---------- ----------- ---------- Net loss ($710,845) ($292,986) ($1,429,459) ($2,196,158) ========== ========== ============ ============ Net loss per common share ($0.03) ($0.01) ($0.05) ($0.08) ======= ======= ======= ======= Weighted average number of common shares outstanding during the period 27,882,828 26,328,874 27,794,716 26,328,874 ========== ========== ========== ==========
- 3 - ENZON, INC. AND SUBSIDIARIES CONSOLIDATED CONDENSED STATEMENTS OF CASH FLOWS Six Months Ended December 31, 1996 and 1995 (Unaudited)
Six Months Ended December 31, December 31, 1996 1995 ------------------------------------------------- Cash flows from operating activities: Net loss ($1,429,459) ($2,196,158) Adjustment for decrease in liability recognized pursuant to Sanofi Winthrop Agreement - (1,312,829) Adjustment for depreciation and amortization 886,729 1,060,971 Non-cash expense for issuance of common stock and stock options 121,838 - Decrease in accrued rent (47,577) (5,158) Decrease in royalty advance - RPR (428,797) (207,855) Changes in assets and liabilities (821,328) (83,597) -------------- ----------- Net cash used in operating activities (1,718,594) (2,744,626) ------------- ------------ Cash flows from investing activities: Capital expenditures (602,700) (48,307) ------------- ------------ Net cash used in investing activities (602,700) (48,307) ------------- ------------ Cash flows from financing activities: Proceeds from issuance of common stock 8,032 - Principal payments of obligations under capital leases (1,283) (1,011) --------------- -------------- Net cash provided by (used in) financing activities 6,749 (1,011) -------------- -------------- Net decrease in cash and cash equivalents (2,314,545) (2,793,944) Cash and cash equivalents at beginning of period 12,666,050 8,102,989 ------------ ---------- Cash and cash equivalents at end of period $10,351,505 $5,309,045 =========== ==========
The accompanying notes are an integral part of these unaudited consolidated condensed financial statements. - 4 - ENZON, INC. AND SUBSIDIARIES Notes To Consolidated Condensed Financial Statements (Unaudited) (1) Organization and Basis of Presentation - ------------------------------------------- The unaudited consolidated condensed financial statements have been prepared from the books and records of Enzon, Inc. and subsidiaries in accordance with generally accepted accounting principles for interim financial information. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting only of normal and recurring adjustments) considered necessary for a fair presentation have been included. Interim results are not necessarily indicative of the results that may be expected for the year. (2) Net Loss Per Common Share - ------------------------------ Net loss per common share is based on the net loss for the relevant period, adjusted for cumulative undeclared preferred stock dividends of $109,000 for the six months ended December 31, 1996 and 1995, and $55,000 for each of the three months ended December 31, 1996 and 1995, divided by the weighted average number of shares issued and outstanding during the period. Stock options, warrants and common stock issuable upon conversion of the preferred stock are not reflected as their effect would be antidilutive for both primary and fully diluted earnings per share computations. (3) Inventories - ---------------- The composition of inventories at December 31, 1996 and June 30, 1996 is as follows: December 31, June 30, 1996 1996 ---- ---- Raw materials $375,000 $206,000 Work in process 298,000 383,000 Finished goods 147,000 396,000 ------- ------- $820,000 $985,000 ======== ======== (4) Cash Flow Information - -------------------------- The Company considers all highly liquid securities with original maturities of three months or less to be cash equivalents. Cash payments for interest were approximately $12,000 and $11,000 for the six months ended December 31, 1996 and 1995, respectively. There were no income tax payments made for the six months ended December 31, 1996 and 1995. During the six months ended December 31, 1996, 24,260 shares of Series B Convertible Preferred Stock were converted into 1,287,213 shares of Common Stock. A cash payment of $2.00 was made for fractional shares related to the conversions. During the six months ended December 31, 1995, the Company issued 150,000 five-year warrants to purchase the Company's common stock at $2.50 per share as part of the commission due to the real estate broker in connection with the termination of the lease at 40 Kingsbridge Road. These transactions are non-cash financing activities. - 5 - ENZON, INC. AND SUBSIDIARIES Notes To Consolidated Condensed Financial Statements, Continued (Unaudited) (5) Significant Agreements - -------------------------- During October 1996, the Company entered into a marketing agreement with Medac GmbH ("MEDAC") to sell ONCASPAR(R) in Europe and Russia. MEDAC will purchase ONCASPAR from Enzon at a set price which will increase over the term of the agreement. The agreement also contains certain minimum annual purchase requirements. (6) Non-Qualified Stock Option Plan - ------------------------------------ During the six months ended December 31, 1996, the Company issued 620,000 stock options at an average exercise price of $2.80 per share under the Company's Non-Qualified Stock Option Plan, as amended, of which 150,000 were granted to executive officers of the Company. None of the options granted during the period are exercisable as of December 31, 1996. All options were granted with exercise prices that equaled or exceeded the fair market value of the underlying stock on the date of grant. (7) Independent Directors' Stock Plan - -------------------------------------- On December 3, 1996, the stockholders voted to approve the Company's Independent Directors' Stock Plan, which provides for compensation in the form of quarterly grants of Enzon common stock to independent directors serving on the Company's Board of Directors. Each independent director is granted shares of Enzon common stock equivalent to $2,500 per quarter plus $500 per Board of Director's meeting attended. The number of shares issued is based on the fair market value of Enzon common stock on the last trading day of the applicable quarter. During the quarter ended December 31, 1996, the Company issued 12,650 shares of Enzon common stock to non-executive directors, pursuant to the Independent Directors' Stock Plan. The shares issued represent payment for services rendered for the period from January 16, 1996 through September 30, 1996. (8) Stockholders' Equity - ------------------------- During the six months ended December 31, 1996, 24,260 shares of Series B Convertible Preferred Stock were converted into 1,287,213 shares of Common Stock. (9) Other Income - ---------------- During the quarter ended December 31, 1995, the Company recognized as other income approximately $1,313,000, representing the unused portion of an advance received under a development and license agreement with Sanofi Winthrop, Inc. ("Sanofi"). During October 1995, the Company learned that Sanofi intended to cease development of PEG-SOD (Dismutec(TM)) due to the product's failure to show a statistically significant difference between the treatment group and the control group in a pivotal Phase III trial. Due, in part, to this product failure, the Company believes it has no further obligations under its agreement with Sanofi with respect to the $1,313,000 advance and therefore, the Company reversed the amount due Sanofi previously recorded as a current liability. - 6 - Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations Information contained herein contains "forward-looking statements" which can be identified by the use of forward- looking terminology such as "believes," "expects," "may," "will," "should," or "anticipates" or the negative thereof or other variations thereon or comparable terminology, or by discussions of strategy. No assurance can be given that the future results covered by the forward-looking statements will be achieved. The matters set forth in Exhibit 99.0 to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1996, which is incorporated herein by reference, constitute cautionary statements identifying important factors with respect to such forward- looking statements, including certain risks and uncertainties, that could cause actual results to vary materially from the future results indicated in such forward-looking statements. Other factors could also cause actual results to vary materially from the future results indicated in such forward-looking statements. Results of Operations - --------------------- Three months ended December 31, 1996 vs. Three months ended December 31, 1995 - ----------------------------------------------------------------------------- Revenues. Revenues for the three months ended December 31, 1996 increased by 7% to $3,559,000 as compared to $3,330,000 for the same period in 1995. The components of revenues are sales and contract revenues. Sales increased by 40% to $3,554,000 for the three months ended December 31, 1996 as compared to $2,542,000 for the same period in the prior year, due to increased revenues from ONCASPAR, which is marketed in the U.S. by Rhone-Poulenc Rorer Pharmaceuticals, Inc. ("RPR"), and increased ADAGEN(R) sales resulting from an increase in patients receiving ADAGEN. ADAGEN sales for the three months ended December 31, 1996 and 1995 were $2,328,000 and $2,039,000, respectively. ONCASPAR revenues are comprised of manufacturing revenues as well as royalties on sales of ONCASPAR by RPR. ONCASPAR revenues increased due to an increase in sales of ONCASPAR by RPR as well as an increase in the royalty rate to 23.5%, as compared to 10.0% during the prior year. Contract revenue for the three months ended December 31, 1996 decreased to $5,000, as compared to $788,000 for the same period in 1995. The decrease was principally due to a one-time payment received during the prior year in connection with the signing of a worldwide non-exclusive licensing agreement with RPR for the Company's Single-Chain Antigen-Binding ("SCA(R)") protein technology. During the three months ended December 31, 1996 and 1995, the Company had export sales of $639,000 and $521,000, respectively. Sales in Europe were $529,000 and $460,000 for the three months ended December 31, 1996 and 1995, respectively. Cost of Sales. Cost of sales, as a percentage of sales, decreased to 28% for the three months ended December 31, 1996 as compared to 48% for the same period in 1995. The decrease was due primarily to a cash payment in the prior year in lieu of satisfying the minimum purchase requirements under the Company's long-term supply agreement for a raw material used in the production of ONCASPAR and the write-off of excess ONCASPAR raw material during the prior year, as well as a decrease in the charge recorded for the three months ended December 31, 1996 for idle capacity at the Company's manufacturing facility. While it is possible that the Company may incur similar losses on its remaining purchase commitments under the supply agreement, the Company does not consider such losses probable, nor can the amount of any loss which may be incurred in the future presently be estimated due to a number of factors, including, but not limited to, potential increased demand for ONCASPAR from RPR, expansion into additional markets outside the U.S. and the possibility that the Company could renegotiate the level of required purchases. If the Company does not achieve increases in sales of ONCASPAR beyond current levels or cannot renegotiate its commitment, a loss would be incurred on the remaining purchase commitment. During the quarter ended December 31, 1996, the Company utilized approximately 31% of its manufacturing capacity for the production of its approved products. Research and Development. Research and development expenses for the three months ended December 31, 1996 decreased by 17% to $1,980,000 from $2,391,000 for the same period in 1995. This decrease was primarily due to reductions in personnel, principally in the clinical and scientific administration areas, and related costs, such as payroll taxes and benefits, totaling approximately $364,000 and other cost containment measures implemented by the Company as part of a continued focus on key development programs. - 7 - Selling, General and Administrative Expenses. Selling, general and administrative expenses for the three months ended December 31, 1996 remained relatively consistent at $1,454,000, as compared to $1,404,000 for the same period in 1995. Other Income/Expense. Other income/expense decreased by $1,238,000 to $158,000 for the three months ended December 31, 1996 as compared to $1,396,000 for the same period last year. The decrease was due principally to the one-time recognition as other income of approximately $1,313,000 during the quarter ended December 31, 1995, representing the unused portion of an advance received under a development and license agreement with Sanofi Winthrop, Inc. ("Sanofi"). Six months ended December 31, 1996 vs. Six months ended December 31, 1995 - ------------------------------------------------------------------------- Revenues. Revenues for the six months ended December 31, 1996 increased by 18% to $7,374,000 as compared to $6,256,000 for the same period in 1995. The components of revenues are sales and contract revenues. Sales increased by 17% to $6,275,000 for the six months ended December 31, 1996 as compared to $5,351,000 for the same period in the prior year, due to increased ONCASPAR revenues from RPR and an increase in ADAGEN sales resulting from an increase in patients receiving ADAGEN. ONCASPAR revenues are comprised of manufacturing revenues as well as royalties on sales of ONCASPAR by RPR. ONCASPAR revenues increased due to an increase in sales of ONCASPAR by RPR as well as an increase in the royalty rate to 23.5%, as compared to 10.0% during the prior year. ADAGEN sales for the six months ended December 31, 1996 and 1995 were $4,453,000 and $4,214,000, respectively. Contract revenue for the six months ended December 31, 1996 increased by 21% to $1,099,000, as compared to $905,000 for the same period in 1995. The increase was due to a one-time $1,000,000 payment, received during the six months ended December 31, 1996, from Schering Corporation ("Schering") related to the transfer of know-how for the manufacturing of PEG-Intron A under the Company's June 1995 amended Schering agreement. Contract revenues for the prior year's period reflected a one-time payment received in connection with a worldwide non-exclusive license for the Company's SCA protein technology signed with RPR. During the six months ended December 31, 1996 and 1995, the Company had export sales of $1,271,000 and $1,162,000, respectively. Sales in Europe were $1,091,000 and $1,014,000 for the six months ended December 31, 1996 and 1995, respectively. Cost of Sales. Cost of sales, as a percentage of sales, decreased to 32% for the six months ended December 31, 1996 as compared to 41% for the same period in 1995. The decrease was due primarily to a cash payment in the prior year in lieu of satisfying the minimum purchase requirements under the Company's long-term supply agreement for a raw material used in the production of ONCASPAR and the write-off of excess ONCASPAR raw material, as well as a decrease in the charge recorded for the six months ended December 31, 1996 for idle capacity at the Company's manufacturing facility. While it is possible that the Company may incur similar losses on its remaining purchase commitments under the supply agreement, the Company does not consider such losses probable, nor can the amount of any loss which may be incurred in the future presently be estimated due to a number of factors, including, but not limited to, potential increased demand for ONCASPAR from RPR, expansion into additional markets outside the U.S. and the possibility that the Company could renegotiate the level of required purchases. If the Company does not achieve increases in sales of ONCASPAR beyond current levels or cannot renegotiate its commitment, a loss would be incurred on the remaining purchase commitment. Research and Development. Research and development expenses for the six months ended December 31, 1996 decreased by 13% to $4,410,000 from $5,081,000 for the same period in 1995. This decrease was primarily due to reductions in personnel, principally in the clinical and scientific administration areas, and related costs, such as payroll taxes, totaling approximately $624,000 and other cost containment measures implemented by the Company as part of a continued focus on key development programs. - 8 - Selling, General and Administrative Expenses. Selling, general and administrative expenses for the six months ended December 31, 1996 remained relatively consistent at $2,730,000, as compared to $2,676,000 for the same period in 1995. Other Income/Expense. Other income/expense decreased by $1,178,000 to $316,000 for the six months ended December 31, 1996 as compared to $1,494,000 for the same period last year. The decrease was due principally to the one-time recognition as other income of approximately $1,313,000 during the quarter ended December 31, 1995, representing the unused portion of an advance received under a development and license agreement with Sanofi. Liquidity and Capital Resources - ------------------------------- Enzon had $10,352,000 in cash and cash equivalents as of December 31, 1996. The Company invests its excess cash in a portfolio of high-grade marketable securities and United States government-backed securities. The Company's cash reserves as of December 31, 1996 decreased by $2,315,000 from June 30, 1996. The decrease in cash reserves was caused by the funding of operations and capital expenditures of $603,000, related to the upgrade of the Company's pilot manufacturing facility for PEG-hemoglobin. The Company's exclusive U.S. marketing rights license with RPR for ONCASPAR provides for a payment of $3,500,000 in advance royalties which was received in January 1995. Under the agreement, as amended, royalties will be offset against a credit of $5,970,000, which represents the royalty advance plus reimbursement of certain amounts due RPR under the previous agreement and interest expense, before cash payments will be made under the agreement. The royalty advance is shown as a long term liability with the corresponding current portion included in accrued expenses on the consolidated condensed balance sheets and will be reduced as royalties are recognized under the agreement. Through December 31, 1996, an aggregate of $1,969,000 in royalties payable by RPR have been offset against the original credit. As of December 31, 1996, 940,808 shares of Series A Cumulative Convertible Preferred Stock ("Series A Preferred Stock") have been converted into 3,093,411 shares of the Company's common stock (the "Common Stock"). Accrued dividends on the converted Series A Preferred Stock in the aggregate of $1,792,000 were settled by the issuance of 232,383 shares of Common Stock. The Company does not presently intend to pay cash dividends on the Series A Preferred Stock. As of December 31, 1996, there were $1,476,000 of accrued and unpaid dividends on the Series A Preferred Stock. These dividends are payable in cash or Common Stock at the Company's option and accrue on the outstanding Series A Preferred Stock at the rate of $218,000 per year. During the quarter ended December 31, 1996, 24,260 shares of the Company's Series B Convertible Preferred Stock were converted into 1,287,213 shares of Common Stock. As of December 31, 1996, there had been no conversion of the Company's Series C Convertible Preferred Stock. Neither the Series B Convertible Preferred Stock nor the Series C Convertible Preferred Stock carry stated dividends. To date, the Company's sources of cash have been the proceeds from the sale of its stock through public and private placements, sales of ADAGEN, sales of ONCASPAR, sales of its products for research purposes, contract research and development fees, technology transfer and license fees and royalty advances. The Company's current sources of liquidity are its cash, cash equivalents and interest earned on such cash reserves, sales of ADAGEN, sales of ONCASPAR, sales of its products for research purposes and license fees. Management believes that its current sources of liquidity will be sufficient to meet its anticipated cash requirements, based on current spending levels, for approximately the next two years. Upon exhaustion of the Company's current cash reserves, the Company's continued operations will depend on its ability to realize significant revenues from the commercial sale of its products, raise additional funds through equity or debt financing, or obtain significant licensing, technology transfer or contract research and development fees. There can be no assurance that these sales, financings or revenue generating activities will be successful. - 9 - PART II OTHER INFORMATION - ------------------------- Item 1. Legal Proceedings - ------------------------- On January 6, 1997, Enzon was served with a complaint by LBC Capital Resources, Inc. ("LBC"), that was filed on December 17, 1996, in the United States District Court for the District of New Jersey (Civil Action No. 96-5919(JCL) asserting that under the May 2, 1995, letter agreement ("Letter Agreement") between Enzon and LBC, LBC was entitled to a commission comprised of $500,000 in cash and warrants to purchase 1,000,000 shares of Enzon common stock at an exercise price of $2.50 per share in connection with the 1996 financing transactions (collectively, the "Financings") the Company entered into with affiliates of Genesee Advisors ("Genesee"). LBC has also asserted that it is entitled to an additional fee of $175,000 in cash and warrants to purchase 250,000 of Enzon common stock when and if Genesee exercises any of the warrants obtained pursuant to the Financings. LBC has claimed $3 million in compensatory damages, plus punitive damages, counsel fees and costs for the alleged breach of the Letter Agreement. The Company believes that no such commission was due under the Letter Agreement and denies any liability under the Letter Agreement. The Company intends to defend this lawsuit vigorously. Item 2. Changes in Securities - ----------------------------- During the period from November 19, 1996 through December 31, 1996, the purchaser of 40,000 shares of the Company's Series B Convertible Preferred Stock in January 1996, converted an aggregate of 24,260 shares of such Series B Convertible Preferred Stock into an aggregate of 1,287,213 shares of Common Stock at per share conversion prices ranging from $1.83 to $1.96. The conversion prices were equal to 80% of the average of the closing bid prices of the Common Stock for the five consecutive trading days ending one trading day prior to the date of such conversion. The Company relied upon the exemption from registration under the Securities Act of 1933, as amended, contained in Section 3(a)(9) thereof with respect to the issuance of such shares of Common Stock upon conversion of the Series B Convertible Stock. Item 4. Submission of Matters to a Vote of Security Holders - ----------------------------------------------------------- (a) An annual meeting of stockholders was held on December 3, 1996. (b) The directors elected at the annual meeting were Peter G. Tombros and Dr. Rosina B. Dixon. The term of office as a director for each of A.M. "Don" MacKinnon, Randy H. Thurman and Robert LeBuhn continued after the annual meeting. (c) The matters voted upon at the annual meeting and the results of the voting, including broker non-votes where applicable, are set forth below. (i)The stockholders voted 23,447,880 shares in favor and withheld 273,020 votes with respect to the election of Peter G. Tombros as a Class I director of the Company and 23,489,276 shares in favor and withheld 231,624 votes with respect to the election of Dr. Rosina B. Dixon as a Class I director of the Company. Broker non-votes were not applicable. (ii) The stockholders voted 22,229,653 shares in favor, 648,481 against, 158,792 abstained and there were 683,974 broker non-votes with respect to a proposal to approve the Company's 1996 Independent Directors' Stock Plan, which will provide for compensation in the form of Enzon common stock for independent directors. (iii)The stockholders voted 23,539,597 shares in favor, 100,112 against and 81,191 abstained with respect to a proposal to ratify the selection of KPMG Peat Marwick LLP to audit the Company's consolidated financial statements for the fiscal year ending June 30, 1997. Broker non-votes were not applicable. - 10 - Item 6. Exhibit and Reports on Form 8-K - --------------------------------------- (a) Exhibits (numbered in accordance with Item 601 of Regulation S-K).
Exhibit Page Number Number Description or ------ ----------- Incorporation By Reference ------------ 3(i) Certificate of Incorporation, as amended ^ 3(ii) By-laws, as amended *(4.2) 10.0 Employment Agreement dated March 25, 1994 with Peter G. Tombros #(10.17) 10.1 Form of Change of Control Agreements dated as of January 20, 1995 entered into with the Company's Executive Officers ~(10.2) 10.2 Lease - 300-C Corporate Court, South Plainfield, New Jersey ***(10.3) 10.3 Modification of Lease - 300-C Corporate Court, South Plainfield New Jersey ++(10.3) 10.4 Lease Termination Agreement dated March 31, 1995 for 20 Kingsbridge Road and 40 Kingsbridge Road, Piscataway, New Jersey ~(10.6) 10.5 Option Agreement dated April 1, 1995 regarding 20 Kingsbridge Road, Piscataway, New Jersey ~(10.7) 10.6 Form of Lease - 40 Cragwood Road, South Plainfield, New Jersey ****(10.9) 10.7 Lease 300A-B Corporate Court, South Plainfield, New Jersey +++(10.10) 10.8 Stock Purchase Agreement dated March 5, 1987 between the Company and Eastman Kodak Company ****(10.7) 10.9 Amendment dated June 19, 1989 to Stock Purchase Agreement between the Company and Eastman Kodak Company **(10.10) 10.10 Form of Stock Purchase Agreement between the Company and the purchasers of the Series A Cumulative Convertible Preferred Stock +(10.11) 10.11 Amendment to License Agreement and Revised License Agreement between the Company and RCT dated April 25, 1985 ++++(10.5) 10.12 Amendment dated as of May 3, 1989 to Revised License Agreement dated April 25, 1985 between the Company and Research Corporation **(10.14) 10.13 License Agreement dated September 7, 1989 between the Company and Research Corporation Technologies, Inc. **(10.15) 10.14 Master Lease Agreement and Purchase Leaseback Agreement dated October 28, 1994 between the Company and Comdisco, Inc. ##(10.16) 10.15 Amendment dated as of May 15, 1995 to Employment Agreement with Peter G. Tombros ~~(10.17) 10.16 Stock Purchase Agreement dated as of June 30, 1995 ~~~(10.16) 10.17 Securities Purchase Agreement dated as of January 31, 1996 ~~~(10.17) 10.18 Registration Rights Agreements dated as of January 31, 1996 ~~~(10.18) 10.19 Warrants dated as of February 7, 1996 and issued pursuant to the Securities Purchase Agreement dated as of January 31, 1996 ~~~(10.19) - 11 - 10.20 Securities Purchase Agreement dated as of March 15, 1996 ^(10.20) 10.21 Registration Rights Agreement dated as of March 15, 1996 ^(10.21) 10.22 Warrant dated as of March 15, 1996 and issued pursuant to the Securities Purchase Agreement dated as of March 15, 1996 ^(10.22) 10.23 Amendment dated March 25, 1994 to License Agreement dated September 7, 1989 between the Company and Research Corporation Technologies, Inc. o 10.24 Independent Directors' Stock Plan o 27.0 Financial Data Schedule o 99.0 Factors to Consider in Connection with Forward-Looking Statements ^^(99.0)
o Filed herewith. * Previously filed as an exhibit to the Company's Registration Statement on Form S-2 (File No. 33- 34874) and incorporated herein by reference thereto. ** Previously filed as exhibits to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1989 and incorporated herein by reference thereto. *** Previously filed as an exhibit to the Company's Registration Statement on Form S-18 (File No. 2- 88240-NY) and incorporated herein by reference thereto. **** Previously filed as exhibits to the Company's Registration Statement on Form S-1 (File No. 2-96279) filed with the Commission and incorporated herein by reference thereto. + Previously filed as an exhibit to the Company's Registration Statement on Form S-1 (File No. 33- 39391) filed with the Commission and incorporated herein by reference thereto. ++ Previously filed as an exhibit to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1992 and incorporated herein by reference thereto. +++ Previously filed as an exhibit to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1993 and incorporated herein by reference thereto. ++++ Previously filed as an exhibit to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1985 and incorporated herein by reference thereto. # Previously filed as an exhibit to the Company's Current Report on Form 8-K dated April 5, 1994 and incorporated herein by reference thereto. ## Previously filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the quarter ended December 31, 1994 and incorporated herein by reference thereto. ~ Previously filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the quarter ended March 31, 1995 and incorporated herein by reference thereto. ~~ Previously filed as an exhibit to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1995 and incorporated herein by reference thereto. ~~~ Previously filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the quarter ended December 31, 1995 and incorporated herein by reference thereto. ^ Previously filed as an exhibit to the Company's Quarterly Report on Form 10-Q for the quarter ended March 31, 1996 and incorporated herein by reference thereto. - 12 - ^^ Previously filed as an exhibit to the Company's Annual Report on Form 10-K for the fiscal year ended June 30, 1996 and incorporated herein by reference thereto. (b) Reports on Form 8-K On December 20, 1996, the Company filed with the Commission a Current Report on Form 8-K dated December 3, 1996 relating to the Company's announcement at the 1996 Annual Meeting of Shareholders that Green Cross Corporation, a Japanese pharmaceutical company, is currently in Phase III clinical trials in Japan for recombinant Human Serum Albumin (rHSA). While the Company's agreement with Green Cross Corporation entitles Enzon to a customary pharmaceutical royalty on product sales, Green Cross has requested a reduction of the royalty. On November 4, 1996, the Company filed with the Commission a Current Report on Form 8-K dated September 27, 1996 relating to (i) its marketing agreement with Medac and (ii) its transfer of know-how for the manufacture of PEG-Intron A to Schering and the Company's receipt of a $1 million payment. - 13 - SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. ENZON, INC. (Registrant) Date: February 14, 1997 By: /S/PETER G. TOMBROS -------------------- Peter G. Tombros President and Chief Executive Officer By: /S/KENNETH J. ZUERBLIS Kenneth J. Zuerblis Vice President, Finance and Chief Financial Officer - 14 -

                                                                 

                     AMENDMENT TO REVISED LICENSE AGREEMENT

         Under  this  Amendment,   effective  March  25,  1994  (the  "Amendment
Effective Date"), Research Corporation Technologies,  Inc., a Delaware nonprofit
corporation,  with offices at 101 N. Wilmot Road, Suite 600, Tucson,  AZ, ("RCT"
or  "LICENSOR"),  and Enzon,  Inc., a Delaware  corporation,  with offices at 40
Kingsbridge  Road,  Piscataway,  New Jersey,  ("Enzon" or  "LICENSEE")  agree as
follows:

                                    ARTICLE I
                                   BACKGROUND

         SECTION  1.1.  RCT  and  Enzon  are  parties  to that  certain  license
agreement made effective August 25, 1985, and subsequently amended (the "Revised
License  Agreement")  under which  Enzon was granted the right to make,  use and
sell certain  complexes  of  polyethylene  glycol  ("PEG") and  polypeptides  of
interest  under the  "PATENT  RIGHTS,"  as such term is defined  in the  Revised
License  Agreement,  and which PATENT  RIGHTS  include  United States Patent No.
4,179,337, issued December 18, 1979, (the "U.S. PEG Patent"). Enzon, the Eastman
Kodak Company  ("Kodak") and Sterling  Winthrop  Inc.,  formerly  Sterling Drug,
Inc., ("Sterling") are parties to that certain agreement made effective June 19,
1989 concerning the development of, inter alia,  complexes of PEG and superoxide
dismutase ("SOD") and the granting of a sublicense to Sterling under the Revised
License  Agreement to make,  use and sell PEG-SOD  (the  "Sterling  Agreement").
Under the Sterling  Agreement,  Enzon,  Kodak,  and Sterling have obligations to
cooperate with RCT in obtaining any patent extension of the U.S. PEG Patent that
may be obtained by RCT and that RCT may desire to obtain.

         SECTION 1.2. Section 156 of Title 35 of the United States Code entitles
RCT to seek  extension  of the term of a United  States  patent for one  product
covered by such patent.

         SECTION 1.3. Enzon desires that RCT agree to seek extension of the term
of the U.S.  PEG Patent,  to the extent such  extension  becomes  available  for
PEG-SOD  and that RCT  agree  not to seek any other  extension  of the U.S.  PEG
Patent based on any other drug product.
RCT is willing to so agree under the following terms and conditions.

         SECTION 1.4. RCT desires to confirm  Enzon's  continuing  obligation to
pay earned royalties during the term of any extension of the PATENT RIGHTS.

                                   ARTICLE II
                                    AMENDMENT

         SECTION  2.1.   Amendment  to  Article  7(a)  of  the  Revised  License
Agreement.  Article 7(a) of the Revise  license  Agreement is hereby  amended by
adding the following paragraph after the second paragraph of Article 7(a):




                  This paragraph shall apply if the term of United States Patent
         4,179,337,  issued  December  18,  1979,  (the "U.S.  PEG  Patent")  is
         extended  beyond  December 18, 1996 pursuant to Section 156 of Title 35
         of the United  States Code and the rights  derived from such  extension
         apply  to  LICENSED  PRODUCTS  in  Field C (the  "PEG-SOD  Extension").
         LICENSEE and LICENSOR  agree and affirm that,  during the period of the
         PEG-SOD  Extension,  if any, the rights and duties of the parties under
         this License  Agreement,  and the terms of this License  Agreement,  as
         they  pertain to LICENSED  PRODUCTS  in Field C  ("PEG-SOD  Products"),
         shall continue in full force and effect  unchanged,  including  without
         limitation LICENSEE's obligations to pay royalties for the manufacture,
         USE or SALE of any PEG-SOD Product, throughout the term of the PEG- SOD
         Extension,  and the parties'  obligations  under  Articles 9 and 16(j).
         Nothing in any  agreement or this  Amendment  shall  affect,  change or
         diminish  LICENSEE's  or any  SUBLICENSEE's  obligation  to pay  earned
         royalties  to  LICENSOR  under  this  License   Agreement  through  the
         expiration of the PEG-SOD Extension,  or any party's  obligations under
         Articles 9 or 16(j).

         SECTION  2.2.  Amendment  to  Add  Article  17 to the  Revised  License
Agreement.  The  Revised  License  Agreement  is hereby  amended  by adding  the
following new Article 17 after Article 16:

         17.      The PEG-SOD Extension.

                  (a)  Obligations  of  LICENSOR.  Unless  LICENSOR and LICENSEE
         otherwise mutually agree, LICENSOR agrees to seek extension of the term
         of U.S.  PEG Patent,  to the extent such  extension is  available,  for
         PEG-SOD  and not to take any  action  or fail to take any  action  that
         would  preclude  or  delay  such  extension,   or  directly  place  the
         availability  of such extension in jeopardy.  So long as the law of the
         United  States  pertaining  to  extension of patents is  understood  or
         interpreted   to  permit  only  one  extension  per  patent  under  the
         provisions  of Section  156 of Title 35 of the United  States Code (and
         other corresponding sections of the law of the United States pertaining
         to patent extension),  LICENSOR agrees not to seek any extension of the
         term of the U.S. PEG Patent for any other  product  covered by the U.S.
         PEG  Patent  under the  provisions  of  Section  156 of Title 35 of the
         United States Code.  The  foregoing in no way  prohibits  LICENSOR from
         seeking  additional  extensions by way of legislative or judicial means
         and in no way prohibits  LICENSOR from seeking other  extensions  under
         Section 156 of Title 35 of the United States Code if such  provision is
         amended (or other provisions are added to the law of the United States)
         to provide for multiple  extensions or is interpreted in a final ruling
         by a court of competent jurisdiction (from which no appeal can be or is
         taken) to permit multiple extensions.

                  (b) Notice of PLA Filing  for FDA  Approval.  If, on or before
         December 18, 1996,  LICENSEE or any  SUBLICENSEE  files with the FDA an
         NDA or a Product  License  Application  ("PLA") seeking FDA Approval to
         market and sell a PEG-SOD Product, LICENSEE shall, immediately after it
         is aware of such filing, notify

                                      - 2 -



         LICENSOR in writing of such filing.  If LICENSOR  becomes aware of such
         filing,  LICENSOR shall immediately  notify LICENSEE in writing of such
         filing.  If neither  LICENSEE nor LICENSOR has received  notice by June
         19, 1996 that the FDA has approved  such NDA or PLA, the parties  shall
         confirm that fact in writing  between  themselves,  the earliest  dated
         confirmation being hereafter referred to as the "Initiating Notice". If
         LICENSEE  or any  SUBLICENSEE  files with the FDA an NDA or PLA seeking
         FDA  approval to market and sell a PEG-SOD  Product and such NDA or PLA
         is approved by the FDA on or before December 18, 1996,  LICENSEE shall,
         immediately  after it is aware of such approval,  give LICENSOR written
         notice (the "Initiating Notice") of such approval.  If LICENSOR becomes
         aware  of such  approval,  LICENSOR  shall  immediately  give  LICENSEE
         written notice (the "Initiating Notice") of such approval.

                  (c) Responsibility for PEG-SOD Extension; Periodic Reports. In
         connection  with  filing for  interim  PEG-SOD  Extensions  (before FDA
         approval of the PEG-SOD Product) and the final PEG-SOD Extension (after
         such FDA  approval)  and any other  PEG-SOD  Extensions  as may  become
         available for any reason,  within ten days after LICENSOR's  receipt or
         issuance of any Initiating  Notice,  LICENSOR shall either:  (i) file a
         complete application with the United States Patent and Trademark Office
         ("USPTO") seeking the then-available PEG-SOD Extension; or (ii) subject
         to  Article  17(d)  below,  grant to  LICENSEE  the power of  attorney,
         substantially  in the form of  Exhibit A attached  hereto,  to seek the
         then-available PEG-SOD Extension (and all subsequent PEG-SOD Extensions
         available) on behalf of LICENSOR.  Concurrently  with the execution and
         delivery of such power of attorney,  LICENSOR shall execute and deliver
         to LICENSEE the Right of Assignee,  substantially  in the form attached
         to the power of  attorney  of Exhibit A. Every two weeks after the date
         of each such Initiating  Notice,  through the date on which the PEG-SOD
         Extension  corresponding  to such  Initiating  Notice  is  obtained  or
         finally denied,  the party undertaking to obtain the PEG- SOD Extension
         (the  "Responsible  Party")  shall report to the other party in writing
         regarding:  (A) the  status  of the  application;  (B) the  Responsible
         Party's  efforts to complete and file the  application  (including  the
         degree  of  cooperation  received  from  any  SUBLICENSEE,  if  such is
         necessary);  (C) any requests or inquiries  received  from the USPTO or
         the FDA,  and the  Responsible  Party's  responses  to such  request or
         inquiries;  and (D) if applicable,  the status of any administrative or
         judicial proceedings concerning the PEG-SOD Extension, its preparation,
         filing or  prosecution.  Although an extension  may be in effect at the
         time of a  particular  Initiating  Notice,  it is the  intention of the
         parties  that all actions  possible  are taken to maximize  and keep in
         effect any PEG-SOD Extension.

               (d) Best Effort Requirement.  The Responsible Party covenants and
          agrees to  exercise  its best  efforts to obtain  each such  extension
          until  each  PEG-SOD  Extension  is either  obtained  or it is finally
          denied by a court of competent  jurisdiction  from which no appeal can
          be taken. The other party shall fully and promptly  cooperate with the
          Responsible Party. "Best efforts" shall include,  without  limitation:
          (i) timely preparing

                                      - 3 -



         and filing a complete application (subject to any delays that may arise
         because a SUBLICENSEE  does not  cooperate  with such  preparation  and
         filing but further subject to the Responsible  Party's obligation below
         to pursue legal  proceedings  to cause any such  SUBLICENSEE to provide
         such  information);  (ii) timely and fully responding to any request by
         the USPTO regarding the application;  (iii)  completely  exhausting any
         administrative  proceedings,  avenues or remedies that may be necessary
         to obtain such  extension;  (iv) timely  bringing  any suit,  appeal or
         other legal  proceeding in a court of competent  jurisdiction to obtain
         such  extension  or to  obtain  the  information  from any  SUBLICENSEE
         necessary to complete the application for the PEG-SOD  Extension and to
         cause such application to be timely filed; and (v) seeking extension by
         virtue of action by any legislative or judicial  authority.  If, in the
         reasonable opinion of the other party, the Responsible Party is failing
         to exercise its best efforts to obtain the PEG-SOD Extension, the other
         party may give the Responsible  Party five days' written notice of such
         opinion.  If the Responsible Party fails, in the reasonable  opinion of
         the other party,  to exercise its best efforts before the expiration of
         such five day period to obtain the PEG-SOD  Extension,  the other party
         may, in addition  to any other  remedies at law or equity,  enforce the
         requirements of this Article 17 through  injunctive  proceedings and an
         action at law or equity. Additionally,  if LICENSEE is the other party,
         LICENSEE may request the court to order  LICENSOR to grant LICENSEE the
         power of  attorney  to prepare  and file the  application  for any such
         PEG-SOD Extension;  if LICENSOR is the other party, LICENSOR may revoke
         the power of  attorney  granted to  LICENSEE  to prepare  and file such
         application  and may undertake to prepare and file such  application on
         LICENSOR's own behalf.  The party from whom  responsibility for seeking
         the PEG-SOD Extension is taken pursuant to the preceding sentence shall
         nonetheless  cooperate  with the  efforts of the other party in seeking
         each and every PEG- SOD Extension.

                  (e)  Grant of Power of  Attorney.  If:  (i)  LICENSOR  has not
         previously  granted  LICENSEE a power of  attorney  to seek any PEG-SOD
         Extension;  (ii)  a PLA or NDA  before  October  19,  1996;  and  (iii)
         LICENSEE has provided  LICENSOR with all  information in its possession
         that LICENSOR may desire for filing the interim  PEG-SOD  Extension but
         LICENSOR has not filed for interim PEG-SOD Extension before October 19,
         1996; then the power of attorney in the form attached to this Agreement
         as Exhibit B shall become  automatically  effective on October 19, 1996
         so as to enable LICENSEE to pursue the PEG-SOD Extension. The foregoing
         provisions  shall  apply with equal  force,  and to the same effect and
         extent,  for any subsequent  interim PEG-SOD  Extension except that the
         pertinent date on which such provision  takes effect for any subsequent
         interim  PEG-SOD  Extension  shall be the date  sixty  days  before the
         expiration of the  then-existing  interim  PEG-SOD  Extension.  If: (A)
         LICENSOR  has not  previously  granted  LICENSEE a power of attorney to
         seek any PEG-SOD  Extension;  (B) the FDA has approved an earlier-filed
         PLA or NDA  for a  PEG-SOD  Product;  and  (C)  LICENSEE  has  provided
         LICENSOR  with all  information  in its  possession  that  LICENSOR may
         desire for filing the final  PEG-SOD  Extension  but  LICENSOR  has not
         filed for final  PEG-SOD  Extension  on or before the later of the date
         twenty days after the date of such

                                      - 4 -


         FDA  approval  or the date five days  after  LICENSOR's  receipt of the
         information  from  LICENSEE;  then the  power of  attorney  in the form
         attached  to the  Agreement  as  Exhibit B shall  become  automatically
         effective  on the 21st day after the date of such FDA approval so as to
         enable LICENSEE to pursue the PEG-SOD Extension.  Concurrently with the
         execution of this amendment to the Revised License Agreement,  LICENSOR
         shall   execute   and   deliver   to   LICENSEE   (or  its   designated
         representative)  the sole and  exclusive  power of attorney to seek any
         and all available PEG-SOD Extension, which power of attorney shall take
         the form of Exhibit B.  Concurrently with the execution and delivery of
         such power of attorney,  LICENSOR shall execute and deliver to LICENSEE
         the Right of Assignee,  substantially in the form attached to the power
         of attorney of Exhibit B. The  effectiveness and validity of such power
         of attorney shall be subject to, and contingent  upon, the satisfaction
         of the conditions specified in this Article 17(e)). LICENSEE shall hold
         such power of attorney in escrow until such time as the  conditions  of
         this  Article  17(e)  are,  in  the  reasonable  opinion  of  LICENSEE,
         satisfied,  at  which  time,  and  only at which  time,  such  power of
         attorney  shall be filed with the United  States  Patent and  Trademark
         Office. LICENSEE acknowledges and agrees that if it files such power of
         attorney  with the  USPTO at a time in which the  foregoing  conditions
         have not been fully satisfied,  such power of attorney shall be revoked
         ab initio and shall have no further force and effect. LICENSOR may seek
         any remedy at law or equity for LICENSEE's  violation of the provisions
         of this Article 17(e).

                  (f) No  Conflicting  Agreements.  Each  party  represents  and
         warrants to the other party that the  provisions  of this Article 17 do
         not violate,  and are not  inconsistent  with or contrary to, any other
         agreement, contract or understanding to which the representing party is
         presently  a party.  Each party  represents  and  warrants to the other
         party that the  representing  party shall not enter into any agreement,
         contract or understanding that would be violated by, inconsistent with,
         or  contrary  to,  the   representing   party's   fulfillment   of  the
         representing party's duties under this Article 17.

     SECTION  2.3.  Amendment  to  Article  1(e)(viii)  of the  Revised  License
Agreement. Article 1(e)(viii) of the Revised License Agreement is hereby changed
to read as follows:

         (viii)   "LICENSED  FIELD" shall mean Fields A, B, C, D, E, F, G, H and
                  I  taken  collectively,  and,  from  and  after  the  date  of
                  extension  of the  license  granted in ARTICLE 2 hereof to any
                  NEW FIELD,  as defined  in clause  (x) of this  ARTICLE  1(e),
                  shall  also  include  each such NEW FIELD so added,  but in no
                  event shall the LICENSED FIELD include the EXCLUDED FIELD.

         SECTION  2.4.   Amendment  to  Article  1(e)  of  the  Revised  License
Agreement.  Article 1(e) often Revised  License  Agreement is hereby  amended by
adding the following subparagraph (xi) after subparagraph (x) of Article 1(e):


                                      - 5 -



         (xi)     "Field  I"  shall  mean  the  making,  Using  and  Selling  of
                  PEG-polypeptide complexes, the polypeptide portion of which is
                  the       enzyme        glucocerebrosidase,        hereinafter
                  "PEG-Glucocerebrosidase."

         SECTION 2.5. Amendment to Article 6 of the Revised Licensed  Agreement.
Article 6 of the  Revised  License  Agreement  is hereby  amended  by adding the
following Paragraph (e) to the end of Article 6:

               (e)  Notwithstanding  the  foregoing,  no License  Issue Fee,  no
          Annual License  Maintenance Fee and no Annual Minimum Royalty shall be
          due or payable by LICENSEE for Field I.

         SECTION 2.6  Continued  Effect.  The Revised  License  Agreement  shall
continue in force and effect unchanged, except as specifically set forth in this
document.


         IN WITNESS  WHEREOF,  the parties  have each  caused a duly  authorized
officer to sign this Amendment  Agreement on the date(s)  indicated below, to be
effective the Amendment Effective Date.


ENZON, INC.                                          RESEARCH CORPORATION
                                                     TECHNOLOGIES, INC.



By:/S/ABRAHAM ABUCHOWSKI                    By:/S/GARY M. MUNSINGER
- ------------------------                    -----------------------
Title:                                      President

Date:March 24, 1994                         Date:March 24, 1994

                                      - 6 -





   

                                   ENZON, INC.
                      1996 INDEPENDENT DIRECTORS STOCK PLAN
                                                                        

     1.  Purpose  and  Persons  Covered.  The  purpose  of the 1996  Independent
Directors  Stock Plan of Enzon,  Inc. is to provide  compensation to Independent
Directors  for  serving on the Board and align  their  economic  interests  more
closely with those of Enzon shareholders.

     2. Definitions.

          (a) "Board" shall mean the Board of Directors of the Company.

          (b) "Common  Stock"  shall mean the $.01 par value Common Stock of the
     Company.

          (c) "Company" shall mean Enzon Inc., a Delaware corporation.

          (d) "Compensation  Committee" shall mean the Compensation Committee of
     the Board.

          (e) "Fair  Market  Value" of a Share of Common Stock as of a specified
     date shall mean (i) the last  reported  sale price of a Share on the NASDAQ
     National  Market on such date or if no Shares are traded on such date, such
     last  reported sale price on the next  following  date on which such Shares
     are  traded,  or  (ii)  the  closing  price  of a  Share  on the  principal
     securities  exchange  on which such Shares are traded on such date or if no
     Shares are traded on such date,  such closing  price on the next  following
     date on which such Shares are traded, or (iii) if the Shares are not traded
     on the NASDAQ National Market or on a securities  exchange,  the average of
     the high bid and low  asked  prices of the  Shares in the  over-the-counter
     market on such date or if no such  prices are  recorded  on such date,  the
     next  following  date on which  such  high  bid and low  asked  prices  are
     recorded. If the Shares are not publicly traded, Fair Market Value shall be
     determined in good faith by the Board.

          (f)  "Independent  Directors"  shall mean members of the Board who are
     not officers and/or employees of the Company.

          (g) "Plan"  shall mean this Enzon,  Inc.  1996  Independent  Directors
     Stock Plan.

          (h) "Share" shall mean one share of Common Stock.




     3. Administrator. The Plan shall be administered, construed and interpreted
by the Compensation Committee or the Board.

     4.  Eligibility.  All Independent  Directors shall participate in the Plan.
Independent  Directors  shall cease to be eligible to participate in the Plan at
the time their membership on the Board of Directors terminates.

     5. Effective Date.  This Plan was approved by the Board  effective  January
15, 1996 (the "Effective  Date");  provided that the Plan shall terminate if the
shareholders of the Company do not approve the Plan on or before March 31, 1997.
The right to receive  Shares in accordance  with the Plan shall be earned by the
Independent  Directors  commencing  as of the Effective  Date;  provided that no
Shares shall be issued to the Independent  Directors hereunder until the Plan is
approved by the  shareholders  of the  Company;  and further  provided  that the
Independent  Directors'  right to the Shares earned hereunder shall terminate if
the Plan is not approved by the  shareholders  of the Company on or before March
31, 1997.

     6. Grant of Shares

          (a)  Quarterly  Grants.  As part of his or her  director's  fee,  each
     Independent  Director  shall be  granted  Shares  equivalent  to $2,500 per
     quarter,  as determined in subsection (b) hereof, plus Shares equivalent to
     $500  per  Board  meeting  attended  by the  Independent  Director  in such
     quarter,  as  determined  in  subsection  (b) hereof.  Subject to Section 5
     hereof,  Shares  granted shall be issued and  delivered to the  Independent
     Director as soon as is  practicable  following the last trading day of each
     quarter provided such Independent  Director has served  continuously on the
     Board during the preceding quarter.

          (b)  Determining   Grant.  The  number  of  Shares  issuable  will  be
     determined by dividing the amount of compensation payable to an Independent
     Director in each quarter by the Fair Market Value of a Share (as defined in
     Section 2 (e)  hereof) on the last day of such  quarter.  A whole  Share of
     Common Stock shall be paid in lieu of any fractional  Share  resulting from
     the computation described in this section.

     7. Shares.  The Shares granted under the Plan shall be Shares of authorized
but unissued or reacquired  Common Stock.  The aggregate  number of Shares which
may be issued under this Plan shall not exceed 240,000, subject to adjustment in
accordance with Section 10 hereof.

                                      - 2 -



     The  limitations  established  by  this  Section  7  shall  be  subject  to
adjustment  upon  the  occurrence  of the  events  specified  and in the  manner
provided in Section 10 hereof.

     8. Terms and Conditions of Shares.

          (a) Rights as a Stockholder. No adjustment shall be made for dividends
     (ordinary or extraordinary,  whether in cash, securities or other property)
     or  distributions or other rights for which the record date is prior to the
     date the Shares are  granted  hereunder,  except as  provided in Section 10
     hereof.  No rights as a stockholder  of the Company as such shall accrue to
     any person hereunder unless and until Shares are granted.

     9. Term of Plan. Shares may be granted pursuant to the Plan until 5:00 p.m.
local time on December 3, 1999.

     10.  Recapitalization.  In the event of a  recapitalization,  stock  split,
stock dividend, combination or exchange of Shares, merger, consolidation, rights
offering,  reorganization  or  liquidation  or any other  similar  change in the
corporate structure of the Company or the Shares, the Compensation  Committee or
the Board may make such equitable adjustments to prevent dilution or enlargement
of rights in the number and class of Shares  authorized to be granted  hereunder
as the Compensation Committee or the Board may deem appropriate.

     11. Securities Law Requirements. No Shares shall be issued unless and until
the  Company  has  determined  that:  (i) it has taken all  actions  required to
register  the Shares  under the  Securities  Act of 1933 or perfect an exemption
from  the  registration   requirements  thereof;  (ii)  any  applicable  listing
requirement of the NASDAQ  National Market or of any stock exchange on which the
Common Stock is then listed has been satisfied;  and (iii) any other  applicable
provision of state or Federal law has been satisfied.

     12.  Termination  or  Amendment  of the  Plan.  The  Board  may at any time
terminate the Plan and may from time to time alter or amend the Plan or any part
thereof;  provided  that, any such  alteration or amendment  shall be subject to
shareholder  approval to the extent required by applicable Federal or state law,
or the  NASDAQ  National  Market or such  other  automated  quotation  system or
national exchange on which the Common Stock may be traded.

     13. No Obligation to Reelect. Nothing in the Plan shall be deemed to create
any obligation on the part of the Board of Directors to nominate any Independent
Director for reelection by the Company's stockholders.

                                      - 3 -



     14.  Governing  Law.  The  provisions  of this Plan shall be  governed  and
construed  in  accordance  with  the  internal  laws of the  State  of  Delaware
applicable to agreements  made and to be performed  entirely  within such state,
without regard to the conflicts of laws provisions thereof.


                                      - 4 -

 


5 This schedule contains summary financial information extracted from the Enzon, Inc. and Subsidiaries Consolidated Condensed Balance Sheet as of December 31, 1996 and the Consolidated Condensed Statement of Operations for the three and six months ended December 31, 1996 and is qualified in its entirety by reference to such financial statements. 3-MOS 6-MOS JUN-30-1996 JUN-30-1996 DEC-31-1996 DEC-31-1996 $10,351,505 $10,351,505 0 0 3,376,915 3,376,915 0 0 820,441 820,441 14,885,784 14,885,784 16,220,391 16,220,391 12,404,047 12,404,047 20,499,199 20,499,199 6,778,565 6,778,565 0 0 0 0 1,447 1,447 290,100 290,100 11,323,322 11,323,322 20,499,199 20,499,199 3,553,975 6,274,566 3,558,985 7,373,875 994,325 1,980,314 4,427,933 9,119,760 0 0 0 0 4,847 11,600 (710,845) (1,429,459) 0 0 (710,845) (1,429,459) 0 0 0 0 0 0 (710,845) (1,429,459) (0.03) (0.05) 0 0