FORM 5 (CONTINUED)

                                    U.S. SECURITIES AND EXCHANGE COMMISSION
                                       WASHINGTON, D.C. 20549
                                       ANNUAL STATEMENT OF CHANGES IN
                                           BENEFICIAL OWNERSHIP
Check this box if no longer
subject to Section 16. Form 4          Filed pursuant to Section 16(a) of the
or Form 5 obligations             Securities Act of 1934, Section 17(a) of the 
may continue                      Public Utility Holding Company Act of 1935 or 
                         Section 30(f) of the Investment Company Act of 1940
 SEE Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
1. Name and Address of Reporting Person 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to Issuer ENZON, INC. (ENZN) (Check all applicable) MACKINNON, A.M. "DON" X Director ______ 10% Owner (Last) (First) (Middle) 3. IRS or Social 4. Statement for Officer ______ Other Security Number of Month/Year (give title below) 31 OLD FARM ROAD Reporting Person JUNE 30, 1995 (specify below) (Voluntary) (Street) 5. If Amendment, Date of Original (Month/Year) DARIEN CT 06820 (City) (State) (Zip) TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED 0.0.1 Title of Security 0.0.2 0.0.3 0.0.4Securities 0.0.5Amount of 0.0.6Owner- 0.0.7Nature (Instr. 3) Trans- Trans- Acquired (A) or Securities ship of action action Disposed of (D) Beneficially Form: Indirect Date Code (Instr. 3, 4 and 5) Owned at End (D) or Beneficial (Month/ (Instr. of Issuer's Indirect Ownership Day/ 8) Fiscal Year (I) (Instr. Year) (Instr. 3 (Instr.4) 4.) and 4) Amount (A) or Price (D)
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over) FORM 5 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED (E.G., puts, calls, warrants, options, convertible securities)
1. Title of Derivative 2.Conver3.Trans-4.Transac-5.Number of6.Date 7.Title and Amount of 8.Price9.Number10. 11. Na- Security sion action tion Deriv- ExercisableUnderlying Securities of of Owner- ture (Instru. 3) or Date Code ative and (Instr. 3 and 4) Deriv-Deriv- ship of In- Exercise(Month/Day/(Instr.SecuritiesExpiration ative ative of De- direct Price Year)8) Ac Date Secur-Secur- Bene- of quired (A) (Month/Day/ ity ities rivative ficial Deriv- or Disposed Year) (Instr.Bene- Own- ative of (D) 5) ficially Security: ership Security (Instr. 3, Owned (D) (Instr. 4) 4, and 5) at or In- End of Direct Year (Instr. (I)(Instr. 4) 4) (A) (D) Date Expira- Title Amount Exer- tion or cisableDate Number of Shares STOCK OPTION (RIGHT TO $2.06 2/21/94 A 20,000 8/21/95 2/21/04 Common Stock 20,000 $2.06 20,000 D -- PURCHASE)+
Explanation of Responses: + Granted under the Company's Non-Qualified Stock Option Plan, as amended, a Rule 16b-3 plan. ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations . /S/A.M. "DON" MACKINNON 2/28/96 SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). **Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, SEE Instruction 6 for procedure.