October 17, 1995

Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C.  20549

Attention:  Filing Desk

     Re:  Enzon, Inc.
          10K/A AMENDMENT TO 1995 ANNUAL REPORT ON FORM 10-K

Dear Sir or Madam:

          On  behalf of Enzon, Inc. a Delaware corporation (the "Company"),
we hereby submit electronically the 10K/A Amendment to the Company's Annual
Report on Form 10-K, filed with the Commission on September 28, 1995.

          This  10K/A is being filed to include Exhibit 27.0, the Financial
Data Schedule, which  was  inadvertently  omitted  from  the  original  10K
filing.

          Manually executed signature pages have been executed prior to the
time of this electronic filing and will be retained by the Company for five
years.

          Please contact the undersigned at (212) 418-0636 at your earliest
convenience with any questions you may have.

                                   Very truly yours,


                                   Kevin T. Collins






                                      SIGNATURES


      Pursuant  to  the  requirements  of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the registrant has  duly  caused this report to be signed
on its behalf by the undersigned, thereunto duly authorized.


                                          ENZON, INC.


                                        /s/Kenneth J. Zuerblis
                                    By: Kenneth J. Zuerblis
                                        Vice  President, Finance
                                        (Principal Financial and
                                        Accounting Officer)




Dated: October 17, 1995





 

5 This schedule contains summary financial information extracted from the Enzon, Inc. and Subsidiaries Consolidated Balance Sheet as of June 30, 1995 and the Consolidated Statement of Operations for the year ended June 30, 1995 and is qualified in its entirety by reference to such financial statements. 12-MOS JUN-30-1995 JUN-30-1995 8,102,989 0 2,362,277 0 792,453 11,442,945 15,758,058 9,968,024 19,184,042 6,920,099 0 263,289 0 1,090 8,033,139 19,184,042 11,024,432 15,826,437 2,918,737 23,112,061 0 0 3,988 (6,291,491) 0 (6,291,491) 0 0 0 (6,291,491) (0.26) 0