0001410578-22-000226 | 10-K | XBRL Viewer | Enzon Pharmaceuticals INC

December 31,

December 31,

Professional and consulting fees

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CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Current assets:
Cash and cash equivalents	$ 47,641	$ 48,142
Royalty receivable	28	31
Other current assets	85	59
Total assets (all current)	47,754	48,232
Current liabilities:
Accounts payable	331	302
Accrued expenses and other current liabilities	72	110
Total current liabilities	403	412
Commitments and contingencies
Stockholders' equity:
Preferred stock - $0.01 par value, authorized 2,960,000 shares; no shares issued and outstanding at December 31, 2021 and 2020
Common stock - $0.01 par value, authorized 170,000,000 shares; issued and outstanding 74,214,603 shares at December 31, 2021 and 2020	742	742
Additional paid-in capital	75,983	78,006
Accumulated deficit	(71,857)	(71,388)
Total stockholders' equity	4,868	7,360
Total liabilities, mezzanine equity and stockholders' equity	47,754	48,232
Series C Preferred Stock
Mezzanine equity:
Series C preferred stock - $0.01 par value, 40,000 shares authorized, issued and outstanding (liquidation value $1,062 per share and $1,012 per share) at December 31, 2021 and 2020	$ 42,483	$ 40,460

CONSOLIDATED BALANCE SHEETS (Parenthetical) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
MEZZANINE EQUITY
Preferred stock, par value (in dollars per share)	$ 0.01	$ 0.01
Preferred stock, shares authorized	2,960,000	2,960,000
Preferred stock, shares issued	0	0
Preferred stock, shares outstanding	0	0
Common stock, par value (in dollars per share)	$ 0.01	$ 0.01
Common stock, shares authorized	170,000,000	170,000,000
Common stock, shares issued	74,214,603	74,214,603
Common stock, shares outstanding	74,214,603	74,214,603
Series C Preferred Stock
MEZZANINE EQUITY
Preferred Shares, par value	$ 0.01	$ 0.01
Preferred Shares, shares authorized	40,000	40,000
Preferred Shares, shares issued	40,000	40,000
Preferred Shares, shares outstanding	40,000	40,000
Preferred Shares, liquidation value	$ 1,062	$ 1,012
Preferred stock, shares authorized	40,000

CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Royalties and milestones, net	$ 701	$ 52
Total revenues	701	52
Operating expenses:
General and administrative	1,170	1,357
Total operating expenses	1,170	1,357
Operating loss	(469)	(1,305)
Other income	7	1
Loss before income tax expense	(462)	(1,304)
Income tax expense	7	7
Net loss	(469)	(1,311)
Dividends on Series C preferred stock	(2,023)	(460)
Net loss available to common shareholders	$ (2,492)	$ (1,771)
Loss per common share
Basic loss per share	$ (0.03)	$ (0.03)
Diluted loss per share	$ (0.03)	$ (0.03)
Weighted average number of common shares
Weighted-average number of common shares outstanding - Basic	74,215	51,100
Weighted-average number of common shares outstanding - Diluted	74,215	51,100

CONSOLIDATED STATEMENTS OF MEZZANINE EQUITY AND STOCKHOLDERS' EQUITY - USD ($) $ in Thousands	Series C Preferred Stock Preferred Stock	Series C Preferred Stock Rights Offering	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Total
Balance at Dec. 31, 2019			$ 442	$ 75,690	$ (70,077)	$ 6,055
Balance (in shares) at Dec. 31, 2019			44,215
Net loss	$ 0		$ 0	0	(1,311)	(1,311)
Preferred stock dividend accumulation	460			(460)		(460)
Rights offering, proceeds net of expenses	$ 40,000		$ 300	2,776		3,076
Rights offering, proceeds net of expenses (in shares)	40		30,000
Balance at Dec. 31, 2020	$ 40,460		$ 742	78,006	(71,388)	7,360
Balance (in shares) at Dec. 31, 2020	40		74,215
Net loss	$ 0		$ 0	0	(469)	(469)
Preferred stock dividend accumulation	2,023			(2,023)		(2,023)
Rights offering, proceeds net of expenses (in shares)		40,000
Balance at Dec. 31, 2021	$ 42,483		$ 742	$ 75,983	$ (71,857)	$ 4,868
Balance (in shares) at Dec. 31, 2021	40		74,215

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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- Definition

Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity.

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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Cash flows from operating activities:
Net loss	$ (469)	$ (1,311)
Changes in operating assets and liabilities:
Decrease (increase) in other current assets and accounts receivable	(23)	(28)
Decrease in refundable tax credit receivable	0	970
Increase (decrease) in accounts payable	29	(22)
(Decrease) increase in accrued expenses and other current liabilities	(38)	11
Net cash used in operating activities	(501)	(380)
Cash flows from financing activities:
Payment of offering costs	0	(524)
Proceeds from rights offering	0	43,600
Net cash provided by financing activities	0	43,076
Net (decrease) increase in cash	(501)	42,696
Cash and cash equivalents at beginning of year	48,142	5,446
Cash and cash equivalents at end of year	47,641	48,142
Series C Preferred Stock
Non-cash financing activities:
Accretion of dividend for Series C Preferred Stock	$ 2,023	$ 460

Description of Business

12 Months Ended

Dec. 31, 2021

Description of Business

Description of Business

(1) Description of Business

Enzon Pharmaceuticals, Inc. (together with its subsidiaries, the “Company,” “Enzon,” “we” or “us”) is positioned as a public company acquisition vehicle, where it can become an acquisition platform and more fully utilize its net operating loss carryforwards (“NOLs”) and enhance stockholder value.

In September 2020, the Company initiated a rights offering for its common and preferred stock (see below and Note 13 to our Condensed Consolidated Financial Statements), which closed in October 2020, and it realized $43.6 million in gross proceeds. This has enabled the Company to embark on its plan to realize the value of its more than $100 million net NOLs by acquiring potentially profitable businesses or assets. To protect the NOLs, in August 2020, the Company’s Board of Directors adopted a Section 382 rights plan (see Note 12 to our Condensed Consolidated Financial Statements).

Historically, the Company had received royalty revenues from licensing arrangements with other companies primarily related to sales of certain drug products that utilized Enzon’s proprietary technology. In recent years, the Company has had no clinical operations and limited corporate operations. Enzon has a marketing agreement in the drug Vicineum, which, if approved, will, potentially, generate milestone and royalty payments to it in the future. Enzon cannot assure you that it will earn material future royalties or milestones.

The Company's Board of Directors (the "Board") and its management are actively involved in pursuing, sourcing, reviewing and evaluating various potential acquisition transactions consistent with its long-term strategy. The Company's management and Board have made a number of contacts and engaged in discussions with principals of individual companies and financial advisors on behalf of various individual companies, while continuing to evaluate potential transactions. To date, no actionable transactions have been initiated.

The Company has a marketing agreement with Micromet AG, now part of Amgen, Inc. (the “Micromet Agreement”), pursuant to which it may be entitled to certain milestone and royalty payments if Vicineum, a drug being developed by Sesen, Inc., is approved for the treatment of non-muscle invasive bladder cancer. In a press release dated February 16, 2021, Sesen announced that the U.S. Food and Drug Administration (the “FDA”) had accepted for filing Sesen’s Biologic License Application (“BLA”) for Vicineum. The FDA further granted Priority Review, with a target Prescription Drug User Fee Act (“PDUFA”) date for a decision on the BLA of August 18, 2021. Accordingly, the Company earned a milestone of $409,430 in the first quarter of 2021, all of which was received by June 30, 2021. However, on August 13, 2021, Sesen announced that it had received a Complete Response Letter (“CRL”) from the FDA and that the FDA had determined that it cannot approve the BLA for Vicineum in its present form and had provided recommendations specific to additional clinical/statistical data and analyses in addition to Chemistry, Manufacturing and Controls (“CMA”) issues pertaining to a recent preapproval inspection and product quality. In a press release that Sesen issued on December 9, 2021, it noted that on December 8, 2021 it had a Clinical Type A meeting with the FDA and received greater clarity regarding the requirements for resubmission of the BLA and trial design, which may include a randomized clinical trial assessing the safety and efficacy of Vicineum compared to investigators’ choice of intravesical chemotherapy. In a filing with the U. S. Securities and Exchange Commission (“SEC”) in March 2021, Sesen noted that it had received notice from the European Medicines Agency (“EMA”) that its Marketing Authorization Application (“MMA”) for Vicineum was found to be valid and the review procedure had officially started. Accordingly, the Company earned and received an additional milestone of $292,284 in the second quarter of 2021. Subsequently, on August 25, 2021, Sesen announced that it had withdrawn its application to market Vicineum in Europe.

During the fourth quarters of 2021 and 2020, we received a license maintenance fee of approximately $28,000 and $30,000, respectively, from Amgen, Inc. in payment of a worldwide, royalty-free non-exclusive right to license Vicineum. The fee represents half of the amount paid by Viventia Biotech (Barbados) Inc. (“Viventia”), part of Sesen, on an annual basis for the continued right to license Vicineum.

In August 2020, the Board adopted a Section 382 rights plan and declared a dividend distribution of one right for each outstanding share of the Company’s common stock to stockholders of record at the close of business on August 24, 2020. (See Note 12 to the Consolidated Financial Statements.)

In September 2020, the Board approved a Rights Offering (the “Rights Offering”), by which the Company distributed, at no charge to all holders of its common stock on September 23, 2020 (the “Record Date”), transferable subscription rights to purchase units (“Units”) at a subscription price per Unit of $1,090. In the Rights Offering, each stockholder on the Record Date received one subscription right for every share of common stock owned on the Record Date. For every 1,105 subscription rights held, a stockholder was entitled to purchase one Unit at the subscription price. Each Unit consisted of one share of newly designated Series C Preferred Stock, par value $0.01 per share, and 750 shares of the Company’s common stock. The subscription period for the Rights Offering ended on October 9, 2020.

As a result of the sale of all 40,000 Units available for purchase in the Rights Offering, the Company received approximately $43.6 million of gross proceeds and had 40,000 shares of Series C Preferred Stock outstanding and an aggregate of 74,214,603 shares of common stock outstanding following the Rights Offering. (See Note 13 to the Consolidated Financial Statements.)

The Company maintains its principal executive offices at 20 Commerce Drive, Suite 135, Cranford, New Jersey 07016 through a service agreement with Regus Management Group, LLC.

Summary of Significant Accounting Policies

12 Months Ended

Dec. 31, 2021

Summary of Significant Accounting Policies

Summary of Significant Accounting Policies

(2) Summary of Significant Accounting Policies

Principles of Consolidation

The consolidated financial statements include the accounts of Enzon Pharmaceuticals, Inc. and its wholly owned subsidiaries. All intercompany balances and transactions have been eliminated as part of the consolidation.

Use of Estimates

The preparation of consolidated financial statements in conformity with accounting principles generally accepted in the United States of America (“U.S. GAAP”) requires management to make estimates and assumptions that affect reported amounts of assets and liabilities, disclosures of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting period. These estimates include legal and contractual contingencies and income taxes. Although management bases its estimates on historical experience, relevant current information and various other assumptions that are believed to be reasonable under the circumstances, actual results could differ from these estimates.

Financial Instruments and Fair Value

The carrying values of cash and cash equivalents, royalty receivable, other current assets, accounts payable, accrued expenses and other current liabilities in the Company’s consolidated balance sheets approximated their fair values at December 31, 2021 and 2020 due to their short-term nature. As of each of December 31, 2021 and 2020, the Company held cash equivalents aggregating approximately $43.6 million.

Revenue Recognition

Royalty revenues from the Company’s agreements with third parties are recognized when the Company can reasonably determine the amounts earned. In most cases, this will be upon notification from the third-party licensee, which is typically during the quarter following the quarter in which the sales occurred. The Company does not participate in the selling or marketing of products for which it receives royalties. Because the Company records revenue only when collection is assured, no provision for uncollectible accounts is established upon recognition of revenues.

Contingent payments due under the Asset Purchase Agreement for the sale of the Company’s former specialty pharmaceutical business are recognized as income when the milestone has been achieved and collection is assured, such payments are non-refundable and no further effort is required on the part of the Company or the other party to complete the earning process.

Income Taxes

Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the estimated future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be realized. The effect of a change in tax rates or laws on deferred tax assets and liabilities is recognized in operations in the period that includes the enactment date of the rate change. A valuation allowance is established to reduce the deferred tax assets to the amounts that are more likely than not to be realized from operations.

Tax benefits of uncertain tax positions are recognized only if it is more likely than not that the Company will be able to sustain a position taken on an income tax return. The Company has no liability for uncertain tax positions. Interest and penalties, if any, related to unrecognized tax benefits would be recognized as income tax expense.

Recent Accounting Pronouncements

12 Months Ended

Dec. 31, 2021

Recent Accounting Pronouncements

Recent Accounting Pronouncements

(3) Recent Accounting Pronouncements

Recent Accounting Standards Updates issued by the Financial Accounting Standards Board (the "FASB") and guidance issued by the Securities and Exchange Commission did not, or are not believed by management to, have a material effect on the Company's present or future consolidated financial statements.

- Definition

The entire disclosure for change in accounting principle. Includes, but is not limited to, nature, reason, and method of adopting amendment to accounting standards or other change in accounting principle.

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+ Details

Accounts Payable and Accrued Expenses

12 Months Ended

Dec. 31, 2021

Accounts Payable

Accounts Payable

(4) Accounts Payable and Accrued Expenses

Prior to 2017, the Company’s primary source of royalty revenues was derived from sales of PegIntron, which is marketed by Merck & Co., Inc. (“Merck”). At December 31, 2020, we recorded a liability to Merck of approximately $302,000, based primarily on Merck’s assertions regarding recoupments related to prior returns and rebates. During the year ended December 31, 2021, additional recoupments claimed by Merck related to PegIntron were approximately $29,000. As such, as asserted by Merck, the Company’s recorded liability to Merck was $331,000 at December 31, 2021. During the year ended December 31, 2020, net royalties from PegIntron were approximately $22,000.

The Company believes that it will receive little or no future royalties from Merck, but may be charged with additional chargebacks from returns and rebates in amounts that, based on current estimates, are not expected to be material.

Accrued expenses and other current liabilities consisted of the following as of December 31, 2021 and 2020 (in thousands):

Stockholders' Equity

12 Months Ended

Dec. 31, 2021

Stockholders' Equity

Stockholders' Equity

(5) Stockholders’ Equity

Preferred Stock

The Company has authorized 3,000,000 shares of preferred stock in one or more series of which, at December 31, 2021, 40,000 shares have been issued, are outstanding and are designated as Series C Preferred Stock in connection with the Rights Offering discussed in Note 14 and 100,000 shares have been designated as Series A-1 Junior Participating Preferred Stock in connection with the August 2020 Section 382 rights plan discussed in Note 12.

Common Stock

As of December 31, 2021, the Company reserved 9,818,392 shares of its common stock for the non-qualified and incentive stock plans.

- Definition

The entire disclosure for shareholders' equity comprised of portions attributable to the parent entity and noncontrolling interest, including other comprehensive income. Includes, but is not limited to, balances of common stock, preferred stock, additional paid-in capital, other capital and retained earnings, accumulated balance for each classification of other comprehensive income and amount of comprehensive income.

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+ Details

Cash Dividend

12 Months Ended

Dec. 31, 2021

Cash Dividend

Cash Dividend

(6) Cash Dividend

No dividend on the shares of the Company's common stock has been paid or declared during the years ended December 31, 2021 and 2020.

Loss Per Common Share

12 Months Ended

Dec. 31, 2021

Loss Per Common Share

Loss Per Common Share

(7) Loss Per Common Share

Basic earnings (loss) per common share (EPS) is calculated by dividing net income (loss), less any dividends, accretion or reduction or redemption on the Company’s Series C Preferred Stock, by the weighted average number of common shares outstanding during the reported period. Restricted stock awards and restricted stock units (collectively, “nonvested shares”) are not considered to be outstanding shares until the service or performance vesting period has been completed.

The diluted earnings per common share calculation would normally involve adjusting both the denominator and numerator as described here if the effect is dilutive.

For purposes of calculating diluted earnings per common share, the denominator normally includes both the weighted-average number of shares of common stock outstanding and the number of common stock equivalents if the inclusion of such common stock equivalents is dilutive. Because a loss was incurred in each of the years ended December 31, 2021 and 2020, common stock equivalents would be anti-dilutive and, accordingly, were excluded from the calculation of diluted loss per share in each of the periods. Dilutive common stock equivalents potentially include stock options and nonvested shares using the treasury stock method and shares issuable under the employee stock purchase plan. During each of the years ended December 31, 2021 and 2020, there were no common stock equivalents. Loss per common share information was as follows (in thousands, except per share amounts) for the years ended December 31, 2021 and 2020:


	2021		2020
Loss per Common Share – Basic and Diluted
Net loss for year	$	(469)	$	(1,311)
Dividends on Series C preferred stock		(2,023)		(460)
Net loss available to common shareholders	$	(2,492)	$	(1,771)

Weighted-average number of common shares outstanding		74,215		51,100

Basic and diluted loss per common share	$	(0.03)	$	(0.03)

At each of December 31, 2021 and 2020, options for 25,000 shares, respectively, were outstanding that have been excluded from the calculation of diluted weighted-average number of shares outstanding, as they would be anti-dilutive, since the respective options’ strike price was greater than the market price of the respective shares.

Stock Options

12 Months Ended

Dec. 31, 2021

Stock Options

Stock Options

(8) Stock Options

Through the Compensation Committee of the Board, the Company administers the 2011 Stock Option and Incentive Plan (the "2011 Plan"), which provides incentive and non-qualified stock option benefits for employees, officers, directors and independent contractors providing services to Enzon. Options granted to employees generally vest over four years from date of grant and options granted to directors vest after one year. The exercise price of the options granted must be at least 100 percent of the fair value of the Company’s common stock at the time the options are granted. Options may be exercised for a period of up to ten years from the grant date. As of December 31, 2020, the 2011 Plan authorized equity-based awards for 5.0 million common shares of which approximately 4.6 million shares remained available for grant. However, this 2011 Plan and the Company’s other stock option plans, including the 2001 Incentive Stock Plan and the 1987 Non-Qualified Stock Option Plan, were terminated effective February 24, 2022 and, as such, there will be no further grants made pursuant these plans.

The following summary of the activity in the Company’s outstanding stock option plans, includes the 2011 Stock Option and Incentive Plan, the 2001 Incentive Stock Plan, and the 1987 Non-Qualified Stock Option Plan and reflects the equitable adjustments approved by the Board (options in thousands):


		Weighted		Weighted
		Average		Average
		Exercise		Remaining		Aggregate
		Price Per		Contractual		Intrinsic
	Options	Option		Term (years)		Value ($000)
Outstanding at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

Vested at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

Exercisable at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

As of December 31, 2021, there was no unrecognized compensation cost related to unvested options that the Company expects to recognize.

No options were granted during the years ended December 31, 2021 and 2020. The options for 25,000 shares of the Company’s common stock that were outstanding at December 31, 2021 expired on January 17, 2022.

During the years ended December 31, 2021 and 2020, the Company recorded no stock-based compensation related to stock options. The Company’s policy is to use newly issued shares to satisfy the exercise of stock options.

The Company received no cash from exercises of stock options during either of the years ended December 31, 2021 and 2020.

Income Taxes

12 Months Ended

Dec. 31, 2021

Income Taxes

Income Taxes

(9) Income Taxes

The components of the income tax provision are summarized as follows (in thousands):


	Year Ended December 31,
	2021		2020
Current:
Federal	$	—	$	—
State and foreign		7		7
Total current		7		7
Deferred:
Federal and state		—		—

Income tax provision	$	7	$	7

The following table represents the reconciliation between the reported income taxes and the income taxes that would be computed by applying the federal statutory rate (21% for years ended December 31, 2021 and 2020) to income before taxes (in thousands):


	Year Ended December 31,
	2021		2020
Income tax provision at federal statutory rate	$	(97)	$	(274)
Add (deduct) effect of:
State income taxes, net of federal tax		(28)		(86)
Expiration of federal research and development credits		1,016		1,039
Change in valuation allowance		(884)		(672)

Income tax provision	$	7	$	7

No federal income tax expense was incurred in relation to normal operating results.

As of December 31, 2021 and 2020, the cumulative tax effects of temporary differences that give rise to the deferred tax assets were as follows (in thousands):


	December 31,		December 31,
	2021		2020
Deferred tax assets:
Federal and state net operating loss carryforward	$	23,530	$	23,398
Research and development credits carryforward		13,780		14,795
Total gross deferred tax assets		37,310		38,193
Less valuation allowance		(37,310)		(38,193)
Net deferred tax assets	$	—	$	—

ASC 740 requires the reduction of deferred tax assets by a valuation allowance if, based on the weight of available evidence, it is more likely than not that some or all of the deferred tax assets will not be realized. For the period ended December 31, 2020, the Company believed that it was more likely than not that future taxable income would not exist to utilize some or all of its deferred tax assets. Accordingly, it recorded a valuation allowance in the amount of its total deferred tax assets for the period ended December 31, 2020. In 2021, the Company generated approximately $468,000 in taxable loss before utilization of NOLs. The Company utilized none of the NOLs due to the taxable loss position. Due to the valuation allowance placed on its deferred tax assets, the deferred tax expense resulting from the usage and/or expiration of deferred tax assets was offset by a corresponding deferred tax benefit from a reduction in valuation allowance, and the Company recorded no deferred tax expense at December 31, 2021. The Company intends to acquire profitable businesses, entities or revenue streams that will generate sufficient income so that it can utilize its approximately $103.4 million NOL. To date, no actionable acquisition candidates have been identified and, while the Company expects that, ultimately, it will be successful in realizing the value of its NOLs, the Company cannot provide assurance that it will be able to do so.

Management of the Company will continue to assess the need for this valuation allowance and will make adjustments when appropriate.

At December 31, 2021, the Company had federal NOLs of approximately $103.4 million, of which approximately $100.6 million will expire in the years 2025 through 2036, and New Jersey state NOLs of approximately $25.7 million that expire in the years 2031 through 2041. Under the Tax Cuts and Jobs Act, federal net operating losses generated in tax years beginning after December 31, 2017 have an unlimited carryforward period, and the amount of net operating loss allowed to be utilized each year is limited to 80% of taxable income.

The Company also had federal research and development (“R&D”) credit carryforwards of approximately $1.0 million that expired in 2021. The Company has remaining R&D credit carryforwards of approximately $13.8 million that expire in the years 2022 through 2029. These deferred tax assets were subject to a valuation allowance such that the deferred tax expense incurred as a result of the expiration of the capital loss and R&D credit carryforwards was offset by a corresponding deferred tax benefit for the related reduction in valuation allowance.

The Company’s ability to use the NOLs and R&D tax credit carryforwards may be limited, as they are subject to certain limitations due to ownership changes as defined by rules pursuant to Section 382 of the Internal Revenue Code of 1986, as amended. However, management of the Company believes that the Company’s NOLs will not be limited by any changes in the Company’s ownership as a result of the successful completion of the Rights Offering. (See Note 13 to the Consolidated Financial Statements.) Additionally, in an effort to protect stockholder value by attempting to protect against a possible limitation on the Company’s ability to use its NOLs, the Board adopted a Section 382 rights plan. (See Note 12 to the Consolidated Financial Statements.)

The Company has not recorded a liability for unrecognized income tax benefits.

- Definition

The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 21
-URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32857-109319

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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+ Details

Significant Agreements

12 Months Ended

Dec. 31, 2021

Significant Agreements

Significant Agreements

(10) Significant Agreements

Merck Agreement

See Note 4 to the Consolidated Financial Statements regarding Merck royalty revenues.

Sesen Agreement

See Note 1 to the Consolidated Financial Statements regarding the Servier milestone obligation to the Company.

Commitments and Contingent Liabilities

12 Months Ended

Dec. 31, 2021

Commitments and Contingent Liabilities

Commitments and Contingent Liabilities

(11) Commitments and Contingent Liabilities

In December 2019, an outbreak of a novel strain of coronavirus (COVID-19) was reported in Wuhan, China. Despite recent progress in the administration of vaccines, both the outbreak of recent variants, including Delta and Omicron, and the related containment measures that have been put in place across the globe, have had and are likely to continue to have a serious adverse impact on the global economy and may adversely affect the Company’s business operations. The ongoing global health crisis (including resurgences) resulting from the pandemic have disrupted, and continue to disrupt, the normal operations of many businesses, including restrictions such as the temporary closure or scale-back of business operations and/or the imposition of either quarantine or remote work requirements for employees, either by government order or on a voluntary basis. It is impossible to predict the effect and ultimate impact of the COVID-19 pandemic, as the situation is continually evolving. The COVID-19 pandemic may continue to disrupt the global supply chain and may cause disruptions to the Company’s operations, financial condition and prospects. At the present time, the Company’s business activities have been largely unaffected by COVID-19 restrictions as the Company’s workforce is comprised solely of independent contractors who are able to perform their duties remotely. However, these restrictions may impact the third parties who are responsible for obtaining final approval of and manufacturing product candidates for which the Company shares the right to receive licensing fees, milestone payments and royalty revenues. If those third parties are required to curtail their business activities for a significant time, or if global supply chain disruptions impact their ability to procure needed resources, raw materials or components, the Company’s right to receive licensing fees, milestone payments or royalties could be materially and adversely affected. Additionally, the development timeline for product candidates being developed by third parties that are pending before the FDA or other regulatory approval could be delayed if the agency is required to shift resources to the review and approval of candidates for treatment of COVID-19. In addition, the effects of the COVID-19 pandemic may negatively impact the Company’s search for a target company, as well as the business and/or results of operations of any target business that the Company acquires or in which the Company invests.

The Company has been involved in various claims and legal actions arising in the ordinary course of business. In the opinion of management, the ultimate disposition of these matters will not have a material effect on the Company’s consolidated financial position, results of operations, or liquidity.

Section 382 Rights Plan

12 Months Ended

Dec. 31, 2021

Section 382 Rights Plan.

Section 382 Rights Plan

(12) Section 382 Rights Plan

On August 14, 2020, in an effort to protect stockholder value by attempting to protect against a possible limitation on the Company’s ability to use its NOLs, the Board adopted a Section 382 rights plan and declared a dividend distribution of one right for each outstanding share of the Company’s common stock to stockholders of record at the close of business on August 24, 2020. Accordingly, holders of the Company’s common stock own one preferred stock purchase right for each share of common stock owned by such holder. The rights are not immediately exercisable and will become exercisable only upon the occurrence of certain events as set forth in the Section 382 rights plan. If the rights become exercisable, each right would initially represent the right to purchase from the Company one one-thousandth of a share of the Company’s Series A-1 Junior Participating Preferred Stock, par value $0.01 per share, for a purchase price of $1.20 per right. If issued, each fractional share of Series A-1 Junior Participating Preferred Stock would give the stockholder approximately the same dividend, voting and liquidation rights as does one share of the Company’s common stock. However, prior to exercise, a right does not give its holder any rights as a stockholder of the Company, including any dividend, voting or liquidation rights. The rights will expire on the earliest of (i) the close of business on June 2, 2024 (unless that date is advanced or extended by the Board), (ii) the time at which the rights are redeemed or exchanged under the Section 382 rights plan, (iii) the close of business on the day of repeal of Section 382 of the Internal Revenue Code or any successor statute or (iv) the close of business on the first day of a taxable year of the Company to which the Company’s Board of Directors determines that no NOLs may be carried forward.

Rights Offering

12 Months Ended

Dec. 31, 2021

Rights Offering.

Rights Offering

(13) Rights Offering

On September 1, 2020, the Board approved a Rights Offering. For every 1,105 subscription rights held, a stockholder was entitled to purchase one Unit at the subscription price of $1,090. Each Unit consisted of one share of newly designated Series C Preferred Stock, par value $0.01 per share, and 750 shares of the Company’s common stock. On October 9, 2020, the Rights Offering expired and, as a result of the sale of all 40,000 Units, the Company received approximately $43.6 million in gross proceeds and issued shares of Series C Preferred Stock and shares of common stock such that, following the closing of the Rights Offering, there was an aggregate of 40,000 shares of Series C Preferred Stock outstanding and 74,214,603 shares of common stock outstanding.

On an annual basis, the Board may, at its sole discretion, cause a dividend with respect to the Series C Preferred Stock to be paid in cash to the holders in an amount equal to 3% of the liquidation preference as in effect at such time (initially $1,000 per share). If the dividend is not so paid in cash, the liquidation preference is adjusted and increased annually by an amount equal to 5% of the liquidation preference per share as in effect at such time, that is not paid in cash to the holders on such date. Holders of Series C Preferred Stock do not have any voting rights and the Series C Preferred Stock is not convertible into shares of the Company’s common stock. The initial liquidation value of the Series C Preferred Stock was $1,000 per share. At December 31, 2021 and 2020, the liquidation value of the Series C Preferred Stock was $1,062 and $1,012 per share, respectively, inasmuch as no dividend was declared or paid in cash. On or after November 1, 2022, the Company may redeem the Series C Preferred Stock at any time, in whole or in part, for an amount based on the liquidation preference per share as in effect at such time. Holders of Series C Preferred Stock have the right to demand that the Company redeem their shares in the event that the Company undergoes a change of control as defined in the Certificate of Designation of the Series C Preferred Stock.

Series C Preferred Stock

12 Months Ended

Dec. 31, 2021

Series C Preferred Stock.

Series C Preferred Stock

(14) Series C Preferred Stock

In October 2020, the Company issued 40,000 shares of Series C Preferred Stock for an aggregate purchase price of $40.0 million.

As of December 31, 2021 and 2020, the Company’s Board of Directors had not declared a cash dividend on the Series C Preferred Stock. Accordingly, during the year ended December 31, 2021, the Company recorded a 5% increase to the liquidation preference of approximately $50 per share of Series C Preferred Stock, aggregating approximately $2,023,000, for a cumulative liquidation value of approximately $42,483,000 ($1,062 per share) as of December 31, 2021 and, as of December 31, 2020, the Company recorded a 5% increase (computed on a pro rata basis) to the liquidation preference of approximately $12 per share of Series C Preferred Stock, aggregating approximately $460,000, for a cumulative liquidation value of approximately $40,460,000 ($1,012 per share).

There is no prohibition on the repurchase or redemption of Series C Preferred Shares while there is any arrearage in the payment of dividends.

Since the redemption of the Series C Preferred Stock is contingently or optionally redeemable, the Series C Preferred Stock has been classified in mezzanine equity on the Consolidated Balance Sheets.

Subsequent Events

12 Months Ended

Dec. 31, 2021

Subsequent Events

Subsequent Events

(15) Subsequent Events

On February 24, 2022, the Company entered into a revised consulting agreement with Richard L. Feinstein, the Company’s Chief Executive Officer, Chief Financial Officer and Secretary. The agreement provides for Mr. Feinstein’s consulting fee to be set at $200,000 per year and an incentive up to 25% of that amount at the discretion of the Board based on the Company’s and Mr. Feinstein’s performance.

In addition, on February 24, 2022, the Board approved an amendment to the Company’s Second Amended and Restated By-Laws to provide that the Board shall no longer require at least three directors but can consist of at least one director.

Summary of Significant Accounting Policies (Policies)	12 Months Ended
Summary of Significant Accounting Policies (Policies)	Dec. 31, 2021
Summary of Significant Accounting Policies
Principles of Consolidation	Principles of Consolidation The consolidated financial statements include the accounts of Enzon Pharmaceuticals, Inc. and its wholly owned subsidiaries. All intercompany balances and transactions have been eliminated as part of the consolidation.
Use of Estimates	Use of Estimates The preparation of consolidated financial statements in conformity with accounting principles generally accepted in the United States of America (“U.S. GAAP”) requires management to make estimates and assumptions that affect reported amounts of assets and liabilities, disclosures of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting period. These estimates include legal and contractual contingencies and income taxes. Although management bases its estimates on historical experience, relevant current information and various other assumptions that are believed to be reasonable under the circumstances, actual results could differ from these estimates.
Financial Instruments and Fair Value	Financial Instruments and Fair Value The carrying values of cash and cash equivalents, royalty receivable, other current assets, accounts payable, accrued expenses and other current liabilities in the Company’s consolidated balance sheets approximated their fair values at December 31, 2021 and 2020 due to their short-term nature. As of each of December 31, 2021 and 2020, the Company held cash equivalents aggregating approximately $43.6 million.
Revenue Recognition	Revenue Recognition Royalty revenues from the Company’s agreements with third parties are recognized when the Company can reasonably determine the amounts earned. In most cases, this will be upon notification from the third-party licensee, which is typically during the quarter following the quarter in which the sales occurred. The Company does not participate in the selling or marketing of products for which it receives royalties. Because the Company records revenue only when collection is assured, no provision for uncollectible accounts is established upon recognition of revenues. Contingent payments due under the Asset Purchase Agreement for the sale of the Company’s former specialty pharmaceutical business are recognized as income when the milestone has been achieved and collection is assured, such payments are non-refundable and no further effort is required on the part of the Company or the other party to complete the earning process.
Income Taxes	Income Taxes Income taxes are accounted for under the asset and liability method. Deferred tax assets and liabilities are recognized for the estimated future tax consequences attributable to differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and operating loss and tax credit carryforwards. Deferred tax assets and liabilities are measured using enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be realized. The effect of a change in tax rates or laws on deferred tax assets and liabilities is recognized in operations in the period that includes the enactment date of the rate change. A valuation allowance is established to reduce the deferred tax assets to the amounts that are more likely than not to be realized from operations. Tax benefits of uncertain tax positions are recognized only if it is more likely than not that the Company will be able to sustain a position taken on an income tax return. The Company has no liability for uncertain tax positions. Interest and penalties, if any, related to unrecognized tax benefits would be recognized as income tax expense.

- Definition

Disclosure of accounting policy for income taxes, which may include its accounting policies for recognizing and measuring deferred tax assets and liabilities and related valuation allowances, recognizing investment tax credits, operating loss carryforwards, tax credit carryforwards, and other carryforwards, methodologies for determining its effective income tax rate and the characterization of interest and penalties in the financial statements.

+ References + Details

Accounts Payable and Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2021

Accounts Payable

Schedule of accrued liabilities

Loss Per Common Share (Tables)

12 Months Ended

Dec. 31, 2021

Loss Per Common Share

Schedule of loss per common share information, basic and diluted

Loss per common share information was as follows (in thousands, except per share amounts) for the years ended December 31, 2021 and 2020:


	2021		2020
Loss per Common Share – Basic and Diluted
Net loss for year	$	(469)	$	(1,311)
Dividends on Series C preferred stock		(2,023)		(460)
Net loss available to common shareholders	$	(2,492)	$	(1,771)

Weighted-average number of common shares outstanding		74,215		51,100

Basic and diluted loss per common share	$	(0.03)	$	(0.03)

Stock Options (Tables)

12 Months Ended

Dec. 31, 2021

Stock Options

Schedule of share-based compensation stock options activity


		Weighted		Weighted
		Average		Average
		Exercise		Remaining		Aggregate
		Price Per		Contractual		Intrinsic
	Options	Option		Term (years)		Value ($000)
Outstanding at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

Vested at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

Exercisable at December 31, 2021 and 2020
December 31, 2020	25	$	1.31		1.05	$	—
Expired and forfeited	—		—		—		—
December 31, 2021	25	$	1.31		0.05	$	—

Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Taxes

Schedule of Components of Income Tax Expense (Benefit)

The components of the income tax provision are summarized as follows (in thousands):


	Year Ended December 31,
	2021		2020
Current:
Federal	$	—	$	—
State and foreign		7		7
Total current		7		7
Deferred:
Federal and state		—		—

Income tax provision	$	7	$	7

Schedule of Effective Income Tax Rate Reconciliation


	Year Ended December 31,
	2021		2020
Income tax provision at federal statutory rate	$	(97)	$	(274)
Add (deduct) effect of:
State income taxes, net of federal tax		(28)		(86)
Expiration of federal research and development credits		1,016		1,039
Change in valuation allowance		(884)		(672)

Income tax provision	$	7	$	7

Schedule of Deferred Tax Assets and Liabilities

As of December 31, 2021 and 2020, the cumulative tax effects of temporary differences that give rise to the deferred tax assets were as follows (in thousands):


	December 31,		December 31,
	2021		2020
Deferred tax assets:
Federal and state net operating loss carryforward	$	23,530	$	23,398
Research and development credits carryforward		13,780		14,795
Total gross deferred tax assets		37,310		38,193
Less valuation allowance		(37,310)		(38,193)
Net deferred tax assets	$	—	$	—

Description of Business (Details) $ / shares in Units, $ in Thousands			1 Months Ended	3 Months Ended			12 Months Ended
	Oct. 31, 2020 USD ($)	Sep. 23, 2020 USD ($) item $ / shares shares	Oct. 31, 2020 USD ($) shares	Dec. 31, 2021 USD ($) $ / shares shares	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($) $ / shares shares	Dec. 31, 2021 USD ($) $ / shares shares	Jun. 30, 2021 USD ($)
Description of Business [Line Items]
Amount of operating loss carry forward				$ 103,400			$ 103,400
Milestone Revenue					$ 409,430
Milestones receivable								$ 292,284
Common Stock, Shares, Outstanding \| shares				74,214,603		74,214,603	74,214,603
Common Stock, Par or Stated Value Per Share \| $ / shares				$ 0.01		$ 0.01	$ 0.01
License Maintenance Fee				$ 28,000		$ 30,000
Royalty receivable				$ 28		$ 31	$ 28
Common Stock, Shares Authorized \| shares				170,000,000		170,000,000	170,000,000
Rights Offering
Description of Business [Line Items]
Rights Offering and realized in gross proceeds	$ 43,600
Series C Preferred Stock
Description of Business [Line Items]
Preferred Stock, Dividend Preference or Restrictions							the holders in an amount equal to 3% of the liquidation preference as in effect at such time (initially $1,000 per share). If the dividend is not so paid in cash, the liquidation preference is adjusted and increased annually by an amount equal to 5% of the liquidation preference per share as in effect at such time, that is not paid in cash to the holders on such date.
Temporary Equity, Aggregate Amount of Redemption Requirement				$ 1,062		$ 1,012	$ 1,062
Rights offering, proceeds net of expenses (Note 2) (in shares) \| shares			40,000
Series C Preferred Stock \| Rights Offering
Description of Business [Line Items]
Rights offering, proceeds net of expenses (Note 2) (in shares) \| shares							40,000
Board of Directors Chairman \| Rights Offering
Description of Business [Line Items]
Subscription Rights To Purchase Unit		$ 1,090
Number Of Subscription Rights To Purchase Unit \| shares		1,105
Board of Directors Chairman \| Series C Preferred Stock \| Rights Offering
Description of Business [Line Items]
Common Stock, Par or Stated Value Per Share \| $ / shares		$ 0.01
Subscription Per Unit \| item		1
Common Stock, Shares Authorized \| shares		750
Servier IPUK Limited [Member]
Description of Business [Line Items]
Royalty Revenue Milestones			$ 43,600
Royalty receivable	$ 100,000		$ 100,000

Summary of Significant Accounting Policies (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Summary of Significant Accounting Policies
Cash Equivalents, at Carrying Value		$ 43,600
Provision for Doubtful Accounts	$ 0

Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Accounts Payable
Professional and consulting fees	$ 61	$ 92
Other	11	18
Accrued Liabilities, Current, Total	$ 72	$ 110

Accounts Payable and Accrued Expenses - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Accounts Payable, Accrued Expenses and Other [Line Items]
Accrued Royalties, Current	$ 29,000
Revenues	701,000	$ 52,000
Royalty [Member]
Accounts Payable, Accrued Expenses and Other [Line Items]
Revenues		22,000
Merck [Member]
Accounts Payable, Accrued Expenses and Other [Line Items]
Due to Related Parties		$ 302,000
Accrued Royalties, Current	$ 331,000

- Definition

Carrying amount as of the balance sheet date of obligations due all related parties.

+ References

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- Definition

Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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Stockholders' Equity (Details) - shares	Dec. 31, 2021	Dec. 31, 2020
Class of Stock [Line Items]
Preferred Stock, Shares Authorized	2,960,000	2,960,000
Non Qualified And Incentive Stock Plans [Member]
Class of Stock [Line Items]
Common Stock, Capital Shares Reserved for Future Issuance	9,818,392
Series A Preferred Stock
Class of Stock [Line Items]
Preferred Stock, Shares Authorized	100,000
Series C Preferred Stock
Class of Stock [Line Items]
Preferred Stock, Shares Authorized	40,000

Cash Dividend (Details) - USD ($) $ in Thousands	12 Months Ended
Cash Dividend (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Cash Dividend
Payments of Ordinary Dividends, Common Stock	$ 0	$ 0

Loss Per Common Share (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Loss per Common Share - Basic and Diluted
Net loss for year	$ (469)	$ (1,311)
Dividends on Series C preferred stock	(2,023)	(460)
Net loss available to common shareholders	$ (2,492)	$ (1,771)
Weighted-average number of common shares outstanding - Basic	74,215	51,100
Weighted-average number of common shares outstanding - Diluted	74,215	51,100
Basic loss per share	$ (0.03)	$ (0.03)
Diluted loss per share	$ (0.03)	$ (0.03)

- Definition

The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.

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The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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Amount, after deduction of tax, noncontrolling interests, dividends on preferred stock and participating securities; of income (loss) available to common shareholders.

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Loss Per Common Share - Additional Information (Details) - shares	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Employee Stock Option [Member]
Antidilutive securities	25,000	25,000

Stock Options - Activity (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Stock Options
Outstanding at December 31, 2020	25
Outstanding at December 31, 2021	25	25
Vested at December 31, 2020	25
Vested at December 31, 2021	25	25
Exercisable at December 31, 2020	25
Exercisable at December 31, 2021	25	25
Weighted Average Exercise Price per Option, Outstanding at December 31, 2020	$ 1.31
Weighted Average Exercise Price per Option, Outstanding at December 31, 2021	1.31	$ 1.31
Weighted Average Exercise Price per Option, Vested at December 31, 2020	1.31
Weighted Average Exercise Price per Option, Outstanding at December 31, 2021	1.31	1.31
Weighted Average Exercise Price per Option, Exercisable at December 31, 2020	1.31
Weighted Average Exercise Price per Option, Exercisable at December 31, 2021	$ 1.31	$ 1.31
Weighted Average Remaining Contractual Term (years), Outstanding at December 31, 2021 and 2020	18 days	1 year 18 days
Weighted Average Remaining Contractual Term (years), Vested at December 31, 2021 and 2020	18 days	1 year 18 days
Weighted Average Remaining Contractual Term (years), Exercisable at December 31, 2021 and 2020	18 days	1 year 18 days
Aggregate Intrinsic Value, Outstanding at December 31, 2021 and 2020	$ 0	$ 0
Aggregate Intrinsic Value, Vested at December 31, 2021 and 2020	0	0
Aggregate Intrinsic Value, Exercisable at December 31, 2021 and 2020	$ 0	$ 0

Stock Options - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Exercise price as percentage of fair value	100.00%
Expiration period	10 years
Unrecognized compensation cost	$ 0
Options granted during the period	0	0
Outstanding shares expired	25,000
Stock-based compensation expense	$ 0	$ 0
Proceeds from Stock Options Exercised	$ 0	$ 0
Two Thousand Eleven Stock Incentive Plan [Member]
Number of shares authorized		5,000,000.0
Number of shares available for grant		4,600,000
Share-based Payment Arrangement, Employee [Member]
Vesting period	4 years
Director
Vesting period	1 year

Income Taxes - Provision components (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Current:
Federal	$ 0	$ 0
State and foreign	7	7
Total current	7	7
Deferred:
Federal and state	0	0
Income tax provision	$ 7	$ 7

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

+ References + Details

Income Taxes - Rate reconciliation (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Taxes
Income tax provision at federal statutory rate	$ (97)	$ (274)
Add (deduct) effect of:
State income taxes, net of federal tax	(28)	(86)
Expiration of federal research and development credits	1,016	1,039
Change in valuation allowance	(884)	(672)
Income tax provision	$ 7	$ 7

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

+ References + Details

Income Taxes - Deferred (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Federal and state net operating loss carryforward	$ 23,530	$ 23,398
Research and development credits carryforward	13,780	14,795
Total gross deferred tax assets	37,310	38,193
Less valuation allowance	(37,310)	(38,193)
Net deferred tax assets	$ 0	$ 0

Income Taxes - Additional information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Income Taxes [Line Items]
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate	21.00%	21.00%
Operating Loss Carryforwards	$ 103,400,000
Tax Credit Carryforward, Limitations on Use	net operating losses generated in tax years beginning after December 31, 2017 have an unlimited carryforward period, and the amount of net operating loss allowed to be utilized each year is limited to 80% of taxable income
Net Operating Loss Carry-Forwards Limitation On Annual Utilization	$ 468,000
Research Tax Credit Carryforward [Member]
Income Taxes [Line Items]
Tax Credit Carryforward, Limitations on Use	The Company has remaining R&D credit carryforwards of approximately $13.8 million that expire in the years 2022 through 2029
Domestic Tax Authority [Member]
Income Taxes [Line Items]
Operating Loss Carryforwards	$ 100,600,000
Domestic Tax Authority [Member] \| Research Tax Credit Carryforward [Member]
Income Taxes [Line Items]
Tax Credit Carryforward Amount	1,000,000.0
NJ State [Member]
Income Taxes [Line Items]
Operating Loss Carryforwards	$ 25,700,000

Section 382 Rights Plan (Details)	Aug. 14, 2020 Vote $ / shares shares	Dec. 31, 2021 $ / shares	Dec. 31, 2020 $ / shares
Preferred stock, par value (in dollars per share) \| $ / shares		$ 0.01	$ 0.01
Section 382 Rights Plan
Rights per share distributed as dividend \| shares	1
Number of preferred stock purchase right for each common stockholder \| shares	1
Section 382 Rights Plan \| Series A-1 Junior Participating Preferred Stock
Number of preferred stock eligible for each warrant become exercisable \| shares	1
Preferred stock, par value (in dollars per share) \| $ / shares	$ 0.01
Purchase price per right \| $ / shares	$ 1.20
Number of votes for fractional share \| Vote	1

Rights Offering (Details) - USD ($) $ / shares in Units, $ in Millions	Oct. 09, 2020	Sep. 01, 2020	Dec. 31, 2021	Dec. 31, 2020
Class of Warrant or Right [Line Items]
Preferred stock, par value (in dollars per share)			$ 0.01	$ 0.01
Number of preferred shares outstanding			0	0
Common stock, shares outstanding			74,214,603	74,214,603
Series C Preferred Stock
Class of Warrant or Right [Line Items]
Liquidation preference per share of preferred stock			$ 50	$ 12
Rights Offering
Class of Warrant or Right [Line Items]
Subscription price per unit of a right		$ 1,090
Number of preferred stock eligible for each warrant become exercisable		1
Number of subscription rights to be held for purchase of a unit		1,105
Number of units entitled for 1,105 subscription rights held		1
Rights Offering \| Series C Preferred Stock
Class of Warrant or Right [Line Items]
Preferred stock, par value (in dollars per share)		$ 0.01
Number of common shares for unit		750
Percentage of dividend on liquidation preference to be paid in cash		3.00%
Liquidation preference per share of preferred stock		$ 1,000	$ 1,062	$ 1,012
Annual increase in percentage of the liquidation preference per share, if dividend not paid in cash		5.00%
Rights Offering \| Investment Agreement \| Series C Preferred Stock
Class of Warrant or Right [Line Items]
Number of units sold	40,000
Number of preferred shares outstanding	40,000
Common stock, shares outstanding	74,214,603
Issued and gross proceeds	$ 43.6

Series C Preferred Stock - Additional Information (Details) - USD ($)		1 Months Ended	12 Months Ended
	Sep. 01, 2020	Oct. 31, 2020	Dec. 31, 2021	Dec. 31, 2020
Stock Issued During Period, Value, New Issues				$ 3,076,000
Series C Preferred Stock
Stock Issued During Period, Shares, New Issues		40,000
Stock Issued During Period, Value, New Issues		$ 40,000,000.0
Preferred Stock, Liquidation Preference Percent			5.00%	5.00%
Preferred Stock, Liquidation Preference, Value			$ 2,023,000	$ 460,000
Preferred Stock Cumulative Liquidation Value			$ 42,483,000	$ 40,460,000
Preferred Stock, Liquidation Preference Per Share			$ 50	$ 12
Rights Offering \| Series C Preferred Stock
Stock Issued During Period, Shares, New Issues			40,000
Percentage of Dividend on Liquidation Preference	3.00%
Preferred Stock, Liquidation Preference Per Share	$ 1,000		$ 1,062	$ 1,012

Subsequent Events (Details) - Subsequent Event - Director - Mr. Feinstein's	Feb. 24, 2022 USD ($)
Subsequent Event [Line Items]
Consulting fee	$ 200,000
Maximum
Subsequent Event [Line Items]
Percentage of bonus	25.00%