UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 12b-25

                           NOTIFICATION OF LATE FILING


                         

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                                                                        SEC FILE NUMBER
                                                                         0-12957

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                                                                        CUSIP NUMBER
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                                                                        0000727510

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(Check one):  _X_ Form 10-K  ___ Form 20-F  ___ Form 11-K  ___ Form 10-Q ___ Form N-SAR  ___ Form N-CSR
                   For Period Ended:  June 30, 2005
                   ___ Transition Report on Form 10-K
                   ___ Transition Report on Form 20-F
                   ___ Transition Report on Form 11-K
                   ___ Transition Report on Form 10-Q
                   ___ Transition Report on Form N-SAR
                   For the Transition Period Ended:_________________________________________________________________


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                     Read Instruction (on back page) Before Preparing Form. Please Print or Type.
 Nothing in this form shall be construed to imply that the Commission has verified any information contained herein.
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If the notification relates to a portion of the filing checked above, identify the Item(s) to which the notification relates:

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PART I - REGISTRANT INFORMATION

Enzon Pharmaceuticals, Inc.
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Full Name of Registrant

Not applicable
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Former Name if Applicable

685 Route 202/206
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Address of Principal Executive Office (Street and Number)

Bridgewater, NJ  08807
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City, State and Zip Code



PART II - RULES 12b-25(b) AND (c)

If the subject report could not be filed without  unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

          (a)  The reasons  described in  reasonable  detail in Part III of this
               form  could  not be  eliminated  without  unreasonable  effort or
               expense

          (b)  The subject annual report,  semi-annual report, transition report
   [X]         on Form 10-K,  Form 20-F,  Form 11-K, Form N-SAR or Form N-CSR or
               portion  thereof,  will  be  filed  on or  before  the  fifteenth
               calendar day  following the  prescribed  due date; or the subject
               quarterly  report of  transition  report on Form 10-Q, or portion
               thereof,  will be filed  on or  before  the  fifth  calendar  day
               following the prescribed due date; and

          (c)  The  accountant's  statement  or other  exhibit  required by Rule
               12b-25(c) has been attached if applicable.


PART III - NARRATIVE State below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q, N-SAR, N-CSR or the transition report or portion thereof, could not be filed within the prescribed time period. The delay in filing is due to the extensive activities required by Enzon Pharmaceuticals, Inc. ("Enzon" or the "Company") in connection with the finalization and filing of restated financial statements for the quarter and fiscal year to date periods ended September 30, 2003, December 31, 2003, March 31, 2004, June 30, 2004, September 30, 2004, December 31, 2004, and March 31, 2005, as previously reported in the Company's current reports on Form 8-K filed with the Securities and Exchange Commission on August 16, 2005 and September 1, 2005. In addition, the Company requires additional time to complete its report on internal control over financial reporting, required of the Company for the first time for the fiscal year ended June 30, 2005 pursuant to Section 404 of the Sarbanes-Oxley Act of 2002. PART IV - OTHER INFORMATION (1) Name and telephone number of person to contact in regard to this notification Craig Tooman, Executive Vice President, Finance and 908 541-8759 Chief Financial Officer - ----------------------------------------- -------------- ------------------- (Name) (Area Code) (Telephone Number) (2) Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If answer is no, identify report(s). Yes _X__ No ___ - -------------------------------------------------------------------------------- (3) Is it anticipated that any significant change in results of operations from the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof? Yes _X__ No ___ If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made. Please see Annex A attached hereto. Enzon Pharmaceuticals, Inc. ________________________________ (Name of Registrant as Specified in Charter) has caused this notification to be signed on its behalf by the undersigned hereunto duly authorized. Date September 13, 2005 By /s/ Craig Tooman Craig Tooman Executive Vice President, Finance and Chief Financial Officer ANNEX A As discussed under Part III herein, the Company is currently preparing restated financial statements for the quarter and fiscal year to date periods ended September 30, 2003, December 31, 2003, March 31, 2004, June 30, 2004, September 30, 2004, December 31, 2004, and March 31, 2005. In connection with the restatement process, Enzon has been undertaking a comprehensive review of its previously issued financial statements. Due to the extensive activities required by the Company in connection with finalizing and filing its restated financial statements for the aforementioned periods it has not yet finalized its financial results for the fourth quarter and fiscal year ended June 30, 2005. However, the following discussion represents the significant changes that the Company currently expects to impact the final results from operations that it will report in its annual report on Form 10-K for the year ended June 30, 2005. As reported in the Company's press release and current report on Form 8-K furnished to the Securities and Exchange Commission (the "Commission") on September 1, 2005, combined product sales for the Company's four internally marketed products decreased to $23.4 million for the quarter ended June 30, 2005, as compared to $27.3 million for the quarter ended June 30, 2004. This decrease was due to a decline in North American sales of the Company's antifungal product, ABELCET(R), due to the previously reported competitive conditions in the intravenous antifungal market. For the quarter ended June 30, 2005, ABELCET sales were $11.3 million as compared to $17.1 million for the quarter ended June 30, 2004. The Company expects to report a decrease in combined product sales for the fiscal year ended June 30, 2005, as compared to the fiscal year ended June 30, 2004 due to these competitive market conditions. In its current report on Form 8-K filed with the Commission on September 1, 2005, the Company also reported that its financial results for the fiscal year ended June 30, 2005 will include a non-cash adjustment to increase the Company's valuation allowance associated with its deferred tax assets as of June 30, 2005. This adjustment is based on the Company's analysis of the continued decline in its ABELCET revenues, as well as the potential impact these conditions may have on its future financial performance. The Company has determined that it is not more likely than not that it would realize the tax benefits from its deferred tax assets. The Company currently expects this non-cash charge to approximate $80 million. The Company's financial results for the fiscal year ended June 30, 2005 will include restructuring charges totaling $2.1 million. In its current report on Form 8-K filed with the Commission on April 21, 2005, Enzon reported its decision to realign its costs through a restructuring due to the aforementioned increasingly competitive conditions in the intravenous antifungal market, as well as the discontinuation of certain development projects in Enzon's research and development pipeline. The restructuring charges were primarily attributable to employee termination benefits. The Company expects a substantial increase in its selling, general and administrative expenses for the fiscal year ended June 30, 2005, as compared to the fiscal year ended June 30, 2004. The increase is primarily attributable to increased sales and marketing costs related to the Company's oncology and hospital-based businesses, as well as increased general and administrative costs principally related to higher accounting fees related to the Company's Sarbanes-Oxley compliance activities, as well as increased personnel-related costs. The Company's discussion of certain financial information for the fourth quarter and year ended June 30, 2005 discussed herein is preliminary and subject to change based on the ongoing review the Company is currently conducting. The Company is currently undergoing an audit of its FY 2005 financial results, and an audit of its internal controls over financial reporting as required by Section 404 of the Sarbanes-Oxley Act of 2002. These audit procedures are not yet complete as of the date of this Notification of Late Filing on Form 12b-25. There can be no assurance that the information disclosed in this filing will not change following the completion of the audits.