UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                                   -----------

                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934



Date of Report (Date of earliest event reported)            September 2, 2005
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                           ENZON PHARMACEUTICALS, INC.
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             (Exact name of registrant as specified in its charter)



          Delaware                   0-12957                  22-2372868
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(State or other jurisdiction   (Commission File No.)   (IRS Identification No.)
     of incorporation)


             685 Route 202/206, Bridgewater, New Jersey      08807
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              (Address of principal executive offices)     (Zip Code)



Registrant's telephone number, including area code         (908) 541-8600
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(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]   Written communication pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

[ ]   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

[ ]   Pre-commencement communication pursuant to Rule 14d-2(b) under the
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[ ]   Pre-commencement communication pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))


Item 8.01 Other Events On September 6, 2005, Enzon Pharmaceuticals, Inc. ("Enzon") issued a press release announcing the appointment of Ivan Horak, M.D. to the position of Executive Vice President, Research and Development and Chief Scientfic Officer. A copy of Enzon's press release dated September 6, 2005 is attached as Exhibit 99.1 to this Current Report and is incorporated herein by reference. Item 9.01 Financial Statements and Exhibits. (c) Exhibits. Exhibit No. Description - ----------- ----------- 99.1 Press Release of Enzon Pharmaceuticals, Inc. dated September 6, 2005

SIGNATURES ---------- Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Dated: September 6, 2005 By: /s/ Craig A. Tooman ------------------- Craig A. Tooman Executive Vice President, Finance and Chief Financial Officer

                                                                    Exhibit 99.1

   Enzon Names Dr. Ivan Horak Chief Scientific Officer

   BRIDGEWATER, N.J.--(BUSINESS WIRE)--Sept. 6, 2005--Enzon
Pharmaceuticals, Inc. (Nasdaq: ENZN) today announced the appointment
of Ivan Horak, M.D. to the position of Executive Vice President of
Research and Development and Chief Scientific Officer. In his new
position Dr. Horak will oversee all aspects of Enzon's research and
development, regulatory affairs, and quality assurance activities.
   Dr. Horak brings an impressive background in drug development to
Enzon and is a board certified medical oncologist. He has held a
number of senior medical and scientific positions in the
pharmaceutical industry, as well as the National Cancer Institute
(NCI).
   "The addition of Dr. Horak to our executive management team
further strengthens the pharmaceutical expertise at Enzon. Dr Horak
will be instrumental in enhancing the productivity of our R&D
pipeline," said Jeffrey H. Buchalter, Enzon's chairman and chief
executive officer. "I have known Dr. Horak professionally for many
years and have full confidence his continued leadership within the
oncology community will contribute greatly to our long-term success in
this therapeutic area."
   Dr. Horak joins Enzon from Immunomedics, Inc. (Nasdaq: IMMU),
where he served as Chief Scientific Officer since July 2003 and
Executive Vice President of Research and Development since May 2002.
Before joining Immunomedics, Dr. Horak was employed by Pharmacia as a
Vice President for Clinical Oncology, where he helped direct the
global development of oncology compounds from 1999 to 2002, including
Camptosar(R) for metastatic colorectal cancer.
   From 1996 to 1999, Dr. Horak held a variety of clinical research
positions at Janssen Research Foundation, a subsidiary of the Johnson
& Johnson Company, including International Director for Clinical
Research and Development, Oncology.
   Prior to joining Janssen, Dr. Horak spent nine years at the NCI
where he most recently served as a cancer expert for the Metabolism
Branch.
   In addition to over 50 scientific publications, Dr. Horak is a
member of several prominent medical societies and has served on
various committees for the American Association for Cancer Research
and the International Union Against Cancer. He also serves on the
editorial board of the prestigious journal, Cancer Research.

   About Enzon

   Enzon Pharmaceuticals is a biopharmaceutical company dedicated to
the development and commercialization of therapeutics to treat
life-threatening diseases. The Company has developed or acquired a
number of marketed products, including PEG-INTRON(R), marketed by
Schering-Plough, and ABELCET(R), ONCASPAR(R), ADAGEN(R), and
DEPOCYT(R), marketed in North America by Enzon's specialized sales
force. Enzon's science-driven strategy includes an extensive drug
development program that leverages the Company's macromolecular
engineering technology platforms, including PEG modification and
single-chain antibody (SCA(R)) technologies. Internal research and
development efforts are complemented by strategic transactions that
provide access to additional marketed products and promising clinical
compounds. Further information about Enzon can be found on the
Company's web site at www.enzon.com.
   All information in this press release is as of September 6, 2005
and the Company undertakes no duty to update this information.

    CONTACT: Enzon Pharmaceuticals, Inc.
             Susan Mesco, 908-541-8678