UNITED STATES
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                 SCHEDULE 13D

                  Under the Securities Exchange Act of 1934
                       (Amendment No.               )*


                                 Enzon, Inc.
- --------------------------------------------------------------------------------
                               (Name of Issuer)


                         Common Stock, $.01 Par Value
- --------------------------------------------------------------------------------
                        (Title of Class of Securities)


                                   29390400
              --------------------------------------------------
                                (CUSIP Number)

    Todd J. Emmerman, Esq., c/o Rosenman & Colin LLP, 575 Madison Avenue,
                      New York, NY 10022 (212) 940-8873
- --------------------------------------------------------------------------------
 (Name, Address and Telephone Number of Person Authorized to Receive Notices
                             and Communications)


                              February 28, 1997
           --------------------------------------------------------
           (Date of Event which Requires Filing of this Statement)



         If the filing person has  previously  filed a statement on Schedule 13G
to report the  acquisition  which is the subject of this  Schedule  13D,  and is
filing this  schedule  because of Rule 13d-1 (b)(3) or (4),  check the following
box / /.

     Note: Six copies of this statement, including all exhibits, should be filed
with the Commission. See Rule 13d-1(a) for other parties to whom copies are to
be sent.

         *The  remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with  respect  to the  subject class of 
securities, and for any subsequent amendment containing information which would
alter disclosures provided in a prior cover page.

         The information required on the remainder of this cover page shall not

be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange
Act of 1934 (the "Act") or otherwise subject to the liabilities of that section
of the Act but shall be subject to all other provisions of the Act (however, see
the Notes).


                                 Page 1 of 46



                                 SCHEDULE 13D

CUSIP No.     29390400

- --------------------------------------------------------------------------------
     1       NAME OF REPORTING PERSON
             S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

               Clearwater Fund IV Ltd.   Employer I.D.# [             ]
- --------------------------------------------------------------------------------
     2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*    (a)  /X/
                                                                  (b)  / /
- --------------------------------------------------------------------------------
     3       SEC USE ONLY
- --------------------------------------------------------------------------------
     4       SOURCE OF FUNDS*

               WC
- --------------------------------------------------------------------------------
     5       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT 
             TO ITEMS 2(d) or 2(e)                                    / /
- --------------------------------------------------------------------------------
     6       CITIZENSHIP OR PLACE OF ORGANIZATION 
               British Virgin Islands
- --------------------------------------------------------------------------------
                          7  SOLE VOTING POWER 
       NUMBER OF

         SHARES                2,359,108 Shares              
                       ---------------------------------------------------------
      BENEFICIALLY        8  SHARED VOTING POWER 

        OWNED BY
                                   0 
          EACH         ---------------------------------------------------------

        REPORTING         9  SOLE DISPOSITIVE POWER

         PERSON
                               2,359,108 Shares
          WITH         ---------------------------------------------------------

                         10  SHARED DISPOSITIVE POWER

                                    0
                  
- --------------------------------------------------------------------------------
     11      AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

               2,359,108 Shares
- --------------------------------------------------------------------------------
     12      CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 

             SHARES*                                                       / /

- --------------------------------------------------------------------------------
     13      PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                  7.7%
- --------------------------------------------------------------------------------
     14      TYPE OF REPORTING PERSON*

                   CO
- --------------------------------------------------------------------------------
                    *SEE INSTRUCTIONS BEFORE FILLING OUT!

                                 Page 2 of 46



                                 SCHEDULE 13D

CUSIP No.      29390400

- --------------------------------------------------------------------------------
     1       NAME OF REPORTING PERSON
             S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

               Clearwater Fund IV, LLC
- --------------------------------------------------------------------------------
     2       CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*  (a)  /X/
                                                                (b)  / /
- --------------------------------------------------------------------------------
     3       SEC USE ONLY
- --------------------------------------------------------------------------------
     4       SOURCE OF FUNDS*

                WC
- --------------------------------------------------------------------------------
     5       CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT 
             TO ITEMS 2(d) or 2(e)                                   / /

- --------------------------------------------------------------------------------
     6       CITIZENSHIP OR PLACE OF ORGANIZATION
               Delaware
- --------------------------------------------------------------------------------
                          7  SOLE VOTING POWER 
       NUMBER OF

         SHARES                2,789,571 Shares(1)              
                       ---------------------------------------------------------
      BENEFICIALLY        8  SHARED VOTING POWER 

        OWNED BY
                                   0 
          EACH         ---------------------------------------------------------

        REPORTING         9  SOLE DISPOSITIVE POWER

         PERSON
                               2,789,571 Shares(1)
          WITH         ---------------------------------------------------------

                         10  SHARED DISPOSITIVE POWER

                                    0                  
- --------------------------------------------------------------------------------
     11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

             2,789,571 Shares(1)
- --------------------------------------------------------------------------------
     12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN 

           SHARES*                                                        / /

- --------------------------------------------------------------------------------
     13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                  9.1%
- --------------------------------------------------------------------------------
     14    TYPE OF REPORTING PERSON*

                   OO

- --------------------------------------------------------------------------------
                    *SEE INSTRUCTIONS BEFORE FILLING OUT!

- -------- 
(1) Includes 2,359,108 Shares of Common Stock beneficially owned by 
Clearwater Fund IV Ltd.

                                 Page 3 of 46



Item 1.      Security and Issuer

             This statement relates to the shares of Common Stock, .01 par
             value per share (the "Common Stock"), of Enzon, Inc. (the
             "Company"), a corporation organized under the laws of the State
             of Delaware. The principal executive offices of the Company are
             located at 20 Kingsbridge Road, Piscataway, New Jersey, 08854.

Item 2.      Identity and Background

             (a)-(c)

             Pursuant to Rule 13d-1(f)(1) promulgated under the Securities 
             Exchange Act of 1934, as amended (the "Exchange  Act"), this 
             Schedule 13D is being filed by Clearwater Fund IV Ltd.(2) 
             ("Clearwater  Ltd.") and Clearwater Fund IV, LLC ("Clearwater
             LLC" and collectively with Clearwater LLC the "Reporting Persons").
             Clearwater Ltd. and Clearwater LLC may be deemed to constitute 
             a group for purposes of this Schedule 13D, due to the fact that 
             Clearwater Ltd. is wholly owned by Clearwater LLC.

             CLEARWATER LTD.

             Clearwater Ltd. is a corporation organized under the laws of the
             British Virgin Islands whose investment strategy is to make
             investments in equity private placements. The principal business
             address of Clearwater Ltd. is CITCO Building, Wickhams Cay, P.O.
             Box 662, Road Town, Tortola, British Virgin Islands.

             The Directors of Clearwater Ltd. are Tortola Corporation Company
             Ltd. ("Tortola"), Hans Frederic Heye and Inter Caribbean Services
             Ltd. ("Inter Caribbean"). The President of Clearwater Ltd. is A.P.
             de Groot. The Vice-President of Clearwater Ltd. is J.M.S.
             Verhooren. The Treasurer of Clearwater Ltd. is Trust Company of
             Willemstad N.V. ("Trust Company"). The Secretary of Clearwater Ltd.
             is Inter Caribbean. Clearwater Ltd. is wholly owned by Clearwater
             LLC.

             The principal business address of Mr. de Groot, Mr. Verhooren,
             Inter Caribbean Services Ltd. and Trust Company is c/o CITCO Fund
             Services (Curacao) N.V., Kaya Flamboyan 9, P.O. Box 812, Curacao,
             Netherland Antilles. The principal business address of Tortola is
             Wickhams Cay, P.O. Box 662, Road Town, Tortola, British Virgin
             Islands. Mr. Heye's principal business address is 611 Druid Road
             East, Suite 200, Clearwater, Florida, 

- -------- 
(2)  In May of 1997 Clearwater Fund IV Ltd. changed its name from GFL 
Performance Fund Ltd. to its present name.

                                 Page 4 of 46





             34616.

             Tortola principally functions as a provider of administrative
             services for offshore funds. Mr. Heye is principally employed as
             the President of the Clearwater Funds, a series of private
             investment entities. Inter Caribbean principally functions as a
             provider of administrative services for offshore funds. Mr. de
             Groot is principally employed as the Account Manager of CITCO Fund
             Services (Curacao) N.V., a provider of administrative services for
             offshore funds. Mr. Verhooren is principally employed as the
             Managing Director of CITCO Fund Services (Curacao) N.V. Trust
             Company principally functions as a provider of administrative
             services for offshore funds.


             CLEARWATER LLC

             Clearwater LLC is a Delaware limited liability company whose
             investment strategy is to make investments in equity private 
             placements. The principal business address of Clearwater LLC
             is 611 Druid Road East, Suite 200, Clearwater, Florida, 34616.
             Mr. Heye is the Managing Member of Clearwater LLC.

             (d) To the best knowledge of the Reporting persons, during the
             last five years, none of the persons named in this Item 2 has 
             been convicted in a criminal proceeding (excluding traffic
             violations or similar misdemeanors).

             (e) To the best knowledge of the Reporting Persons, during the
             last five years, none of the persons names in this Item 2 was a
             party to a civil proceeding of a judicial or administrative body
             of competent jurisdiction which as a result of such proceeding 
             was or is subject to any judgment, decree or final order
             enjoining future violations of, or prohibiting or mandating 
             activities  subject to, Federal or state securities laws or
             finding any violation with respect to such laws.

             (f) Mr. Heye is a United States citizen. Mr. de Groot and Mr.
             Verhooren are both citizens of the Netherlands.

Item 3.      Source and Amount of Funds or Other Consideration.

             The amount of funds used by Clearwater Ltd. to purchase the 595,157
             shares of Common Stock it now owns as a result of the Series B
             Agreement (as defined below in Item 6) is $1,630,730.  The 273,723
             $4.11 Warrants (as defined below in Item 5) owned by Clearwater
             Ltd., were issued to Clearwater Ltd. contemporaneously with the
             issuance to GFL Advantage Fund Ltd. ("Advantage") of

                                 Page 5 of 46




             40,000 shares of the Company's Series B Convertible Preferred Stock
             for no extra purchase price.

             Clearwater  Ltd. acquired 1,015,228 shares of the Company's 
             Common Stock by converting  its 20,000 shares of Series D
             Preferred Stock (as defined below in Item 6); Clearwater Ltd.
             acquired the shares of Series D Preferred Stock when it exchanged 
             its shares of Series C Preferred  Stock (as defined below in Item
             6). The amount of funds used by  Clearwater  Ltd. to purchase the
             shares of Series C Preferred Stock was $2,000,000. 
             Contemporaneously with the issuance to Clearwater Ltd. of the
             shares of Series C Preferred Stock, Clearwater Ltd. was issued
             200,000  $5.625  Warrants (as that term is defined below), for no
             extra purchase price.

             Clearwater Ltd. purchased 275,000 shares of the Company's Common
             Stock on the open market, for an aggregate purchase price of
             $687,500.

             The amount of funds used by Clearwater LLC to purchase 364,962
             $4.11 Warrants (as defined below in Item 5) was $219,064.73.

             The amount of funds used by Clearwater LLC to purchase 18,000 
             shares of the Company's Common Stock on the open market on March
             31, 1997 was $46,125.

             The amount of funds used by Clearwater LLC to purchase 47,500 
             shares of the Company's Common Stock on the open market on April
             30, 1997 was $137,498.25.

             The source of all funds referred to in this Item 3 was working
             capital.

Item 4.      Purpose of Transaction.

             The Reporting Persons acquired the securities reported herein as 
             being beneficially owned by the Reporting Persons for investment  
             purposes.  Depending upon market conditions and other factors that 
             each of the Reporting Persons may deem material to their 
             respective investment decisions, the Reporting Persons may 
             purchase additional shares of the securities of the Company in
             the open market or in private transactions, or may dispose of
             all or a portion of the securities of the Company that each owns or
             hereafter may acquire.  In addition, Clearwater Ltd. has agreed not
             to sell any of the shares of the Company's Common Stock received
             by it upon  conversion of the Series D Preferred Stock, on or
             before February 28, 1998. Except as otherwise set forth herein, 
             the Reporting Persons have no plans or proposals which relate 
             to, or could result in any matters referred to in paragraphs (b)
             through (j) of Item 4 of Schedule 13D.

                                 Page 6 of 46





Item 5.      Interest in Securities of the Issuer.

             (a)-(b)

             According to the Company's Quarterly Report on Form 10-Q for the
             period ended March 31, 1997, there were, as of May 7, 1997,
             30,796,174 shares of Common Stock of the Company outstanding.

             Clearwater Ltd.

             For purposes of this Schedule 13D, Clearwater Ltd. beneficially
             owns 2,359,108 shares of the Company's Common Stock (comprising
             7.7% of the outstanding  Common Stock of the Company as of May 7,
             1997) by virtue of the following:

             (i) Clearwater Ltd. owns 1,885,385 shares of the Company's Common
             Stock. 595,157 of said shares  were acquired pursuant to the
             Series B Agreement (as defined blow in Item 6). 1,015,228 of said
             shares were received by Clearwater Ltd. upon its conversion of its
             20,000 shares of Series D Preferred Stock. Clearwater Ltd. has
             agreed not to sell the shares which it received through the
             conversion of Series D Preferred Shares before February 28, 1998. 
             Clearwater Ltd. acquired 275,000 shares of the Company's Common
             Stock on the open market.

             (ii) Clearwater Ltd. owns 273,723 warrants to purchase shares of
             the Company's Common Stock at any time before February 7, 2001 at
             the purchase price of $4.11 per share (the  "$4.11 Warrants").

             (iii) Clearwater Ltd. owns 200,000 warrants to purchase shares of
             the Company's Common Stock at any time before March 15, 2001 at the
             purchase price of $5.625 per share (the "$5.625 Warrants").

             Clearwater Ltd. has the sole power to vote and dispose of all such
             shares.

             Clearwater LLC

             For purposes of this Schedule 13D, Clearwater LLC beneficially 
             owns 2,789,571 shares of the Company's Common Stock (comprising
             9.1% of the outstanding  shares of the Company's Common Stock as of
             May 7, 1997) by virtue of the following:

             (i) Clearwater LLC beneficially owns the 2,359,108 shares of Common
             Stock which are beneficially owned by Clearwater Ltd. by virtue of
             the fact that Clearwater Ltd. is wholly owned by Clearwater LLC.


                                       Page 7 of 46





             (ii) Clearwater LLC owns 364,963 $4.11 Warrants.

             (iii) Clearwater LLC owns 65,500 shares of the Common Stock which
             it acquired on the open market.

             Clearwater LLC has the sole power to vote and dispose of all such
             shares.

             (c) Clearwater LLC purchased  47,500 shares of the Company's Common
             Stock on the open market on April 30, 1997 at an average purchase
             price of $2.8947.

             (d)  Each of the  Reporting  Persons  affirms  that no  person 
             other  than  the Reporting  Persons has the right to receive,  or
             the power to direct the receipt of dividends  from,  or the
             proceeds from the sale of, the Common Stock owned by the Reporting
             Persons.

             (e) It is  inapplicable  for the purposes  herein to state the date
             on which the Reporting  Persons  ceased to be the  owners of more 
             than five  percent  of the Company's Common Stock.

Item 6.      Contracts, Arrangements, Understandings or Relationships With 
             Respect to Securities of the Issuer.

             Pursuant to the Securities Purchase Agreement, by and among
             the Company and Clearwater  Ltd. and Advantage dated as of
             January 31, 1996 (the "Series B Agreement"), Clearwater Ltd.
             purchased 1,094,890 shares of the Company's Common Stock at a 
             purchase price of $2.74 per share and Advantage purchased 
             40,000 shares of Series B Convertible Preferred Stock of the 
             Company for a purchase price of $4,000,000. Contemporaneous with
             the issuance of said shares of Series B Convertible Preferred 
             Stock the Company issued 273,723 $4.11 Warrants to Clearwater
             Ltd. and 364,962 $4.11 Warrants to Advantage and the parties
             executed Warrant Certificates relating to both issuances of $4.11
             Warrants on February 7, 1997.

             Pursuant to that certain Registration Rights Agreement,  dated as
             of January 31, 1997 by and among the Company,  and Clearwater Ltd.
             and Advantage (the "Series B Registration  Rights  Agreement"), 
             the  Company  agreed to file a  registration statement  covering
             the public sale of the shares of Common Stock  receivable by
             Clearwater Ltd. and Advantage as a result of the Series B
             Agreement.

             Pursuant to that certain Securities  Purchase  Agreement,  dated as
             of March 15, 1996 (the "Series C Agreement") by and between the
             Company and Clearwater  Ltd., Clearwater Ltd.  purchased  20,000
             shares of the Company's  Series C Convertible Preferred Stock,
             $0.01 par value


                                       Page 8 of 46




             per share (the "Series C Preferred Stock") for a purchase price of
             $2,000,000.

             Pursuant to that certain  Registration  Rights Agreement,  dated as
             of March 15, 1996, by and between the Company and Clearwater Ltd.
             (the "Series C Registration Rights Agreement"), the Company agreed
             to file a registration statement covering the public sale of the
             shares  receivable by Clearwater  Ltd. upon conversion of the
             shares of Series C Preferred Stock owned by Clearwater Ltd.

             On March  15,  1996,  the  Company  issued to  Clearwater  Ltd. 
             200,000  $5.625 Warrants.  On even date with said  warrant 
             issuance,  the  parties  executed  a Warrant Certificate relating
             to the $5.625 Warrants.

             Pursuant to that  certain  Stock  Exchange  Agreement,  dated as of
             February 28, 1997, (the "Stock Exchange Agreement") by and between
             the Company and Clearwater Ltd.,  Clearwater  Ltd.  exchanged its
             shares of Series C Preferred Stock for an equal number of the
             Company's Series D Convertible  Preferred  Stock,  $0.01 par value
             share (the "Series D Convertible  Preferred Stock") and agreed not
             to sell or otherwise  transfer the shares of Common Stock issued
             upon  conversion of the Series D Preferred  Stock before  February
             28, 1998.  In addition,  the parties agreed  that the  rights  and 
             obligations  of the  parties  under the  Series C Registration 
             Rights  Agreement  with respect to shares of the Company's  Common
             Stock  receivable by Clearwater  Ltd. upon  conversion of the
             shares of Series C Preferred  Stock  would  attach  to the  shares
             of Common  Stock  issuable  upon conversion of the shares of Series
             D Preferred Stock,  provided,  however,  that the obligation of the
             Company to file a  registration  statement with respect to the
             shares of Common  Stock  issuable  upon  exercise  of the Series D
             Preferred Stock would not commence  until  September  17, 1997.  On
             the day that the Stock Exchange Agreement was executed,  Clearwater
             Ltd. converted all of its shares of Series D Preferred Stock into
             1,015,228 shares of the Company's Common Stock.

             Pursuant to that certain Warrant Purchase and Sale Agreement, 
             dated as of March 10, 1997, by and between Advantage and Clearwater
             LLC,  Clearwater LLC purchased 364,963 $4.11 Warrants from
             Advantage.

Item 7.      Material to be Filed as Exhibits

             1. Agreement, dated May 27, 1997, among the Reporting Persons
             relating to filing of a joint acquisition statement pursuant to
             Rule 13d-1(f)(1).


             2.  Warrant Certificates relating to the issuance to

                                       Page 9 of 46





             Clearwater Ltd. of the $4.11 Warrants.

             3.  Warrant Certificate relating to the issuance to Clearwater Ltd.
             of the $5.625 Warrants.

             4. Warrant  Purchase and Sale  Agreement  between  Advantage and 
             Clearwater LLC relating to the purchase by Clearwater LLC of $4.11
             Warrants.




                                Page 10 of 46




                                  SIGNATURE


         After reasonable inquiry,  and to the best of our knowledge and belief,
the  undersigned  certify that the  information  set forth in this  statement is
true, complete and correct.

Dated: May 27, 1997


                                  CLEARWATER FUND IV LTD.

                                          /s/ A.P. de Groot
                                          ---------------------------- 
                                          By:  A.P. de Groot
                                          Title:   President



                                          CLEARWATER FUND IV, LLC

                                          /s/ Hans Frederic Heye
                                          ----------------------------
                                          By:   Hans Frederic Heye
                                          Title:   Managing Member



                                Page 11 of 46





                                Exhibit Index


                                                                    Sequentially
Exhibit No.                  Description                           Numbered Page
- -----------                  -----------                           -------------

    1.          Agreement, dated May 27, 1997, among the 
                Reporting Persons relating to filing of a 
                joint acquisition statement pursuant to 
                Rule 13-d(f)(1).


    2.          Warrant Certificate of Enzon, Inc. 
                representing the right of Clearwater Fund IV 
                Ltd. to purchase 273,723 shares of Common
                Stock.


    3.          Warrant Certificate of Enzon, Inc. representing 
                the right of Clearwater Fund IV Ltd. to purchase 
                200,000 shares of Common Stock.

    4.          Warrant Purchase and Sale Agreement between 
                GFL Advantage Fund Ltd. and Clearwater Fund IV, 
                LLC, dated as of March 14, 1997.





                                Page 12 of 46




                                                                      Exhibit 1


         The undersigned hereby agree, pursuant to Rule 13d-1(f)(1) to file a
joint statement on Schedule 13D and amendments thereto pertaining to their
beneficial ownership of shares of Common Stock of Enzon, Inc.

         This agreement may be terminated for any reason by any party hereto
immediately upon the personal delivery or facsimile transmission of notice to
that effect to the other parties hereto.

         This agreement may be executed in counterparts and all so executed
shall constitute one agreement.

Date:  May 27, 1997


                                CLEARWATER FUND IV LTD.

                                /s/ A.P. de Groot
                                ----------------------------
                                By:   A.P. de Groot
                                Title:   President



                                CLEARWATER FUND IV, LLC

                                /s/ Hans Frederic Heye
                                -----------------------------
                                By:   Hans Frederic Heye
                                Title:   Managing Member




                                Page 13 of 46



                                  EXHIBIT 2

                  WARRANT TO PURCHASE 273,723 SHARES OF COMMON STOCK VOID AFTER
5:00 P.M., NEW JERSEY TIME, ON FEBRUARY 7, 2001. THIS WARRANT AND THE SHARES OF
COMMON STOCK ISSUABLE UPON THE EXERCISE HEREOF HAVE BEEN AND WILL BE ISSUED IN
TRANSACTIONS WHICH HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE "ACT"), OR UNDER ANY STATE SECURITIES OR BLUE SKY LAWS. THIS
WARRANT AND SUCH SHARES MAY NOT BE SOLD, TRANSFERRED, PLEDGED, HYPOTHECATED OR
OTHERWISE DISPOSED OF, IN WHOLE OR IN PART, IN THE ABSENCE OF AN EFFECTIVE
REGISTRATION STATEMENT UNDER THE ACT AND APPLICABLE STATE LAW, OR AN OPINION OF
COUNSEL ACCEPTABLE TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED.



NO. 2                                                             273,723 SHARES


                                 ENZON, INC.

                  This certifies that, for value received, GFL Performance Fund
Ltd., the registered holder hereof, or assigns (the "Warrantholder") is entitled
to purchase from Enzon, Inc., a Delaware corporation (the "Company"), at any
time on and after the earlier of the date the Registration Statement (filed with
the Securities and Exchange Commission (the "SEC") pursuant to Section 2(a) of a
certain Registration Rights Agreement of even date herewith by and among the
parties hereto) is declared effective by the SEC or seventy (70) days from the
date of issuance of this Warrant and before 5:00 p.m., New Jersey time, on
February 7, 2001 (the "Termination Date"), at the purchase price of $4.11 per
share (the "Exercise Price"), the number of shares of Common Stock, par value
$.01 per share (the "Common  Stock"), of the Company set forth above (the
"Warrant Stock"); provided, however, that in no event shall the Warrantholder be
entitled to exercise this Warrant if, after giving effect to such exercise,  the
number of shares of Common Stock beneficially owned by the Warrantholder and all
other holders of Common Stock whose holdings would be aggregated with the
Warrantholder for purposes of calculating beneficial ownership in accordance
with Sections 13(d) and 16 of the Securities Exchange Act of 1934, as amended,
and the regulations thereunder ("Sections  13(d) and 16"), including without
limitation any person serving as an adviser to any holder (collectively, the
"Related Persons"), would exceed four and  nine-tenths percent  (4.9%) of the
outstanding shares of Common Stock (calculated in accordance with Sections 13(d)
and 16). The Common Stock issuable upon conversion of shares of the Company's
preferred stock or exercise of warrants for the purchase of Common Stock held by
the Warrantholder or the Related

                                Page 14 of 46



Persons shall not be deemed to be beneficially owned by the Warrantholder or
such Related Persons for this purpose.  The number of shares of Warrant  Stock,
the Termination Date and the Exercise Price per share of this Warrant shall be
subject to adjustment from time to time as set forth below.


SECTION 5.  TRANSFER OR EXCHANGE OF WARRANT

             The Company  shall be entitled to treat the Warrantholder as the 
owner in fact hereof for all purposes and shall not be bound to recognize
any equitable or other claim to or interest in this Warrant on the part of any
other person. This Warrant shall be transferable only on the books of the
Company, maintained at its principal office, upon delivery of this Warrant
Certificate duly endorsed by the Warrantholder or by its duly authorized
attorney or representative, or accompanied by proper evidence of succession,
assignment or authority to transfer.  Upon any registration of transfer, the
Company shall deliver a new Warrant  Certificate or Certificates to the persons
entitled thereto.

SECTION 6.  TERM OF WARRANT; EXERCISE OF WARRANTS

             A.  Termination.  The Company may, in its sole discretion, extend 
the Termination Date with respect to the exercise of this Warrant upon notice to
the Warrantholder.  As used herein, "Termination Date" shall be deemed to
include any such extensions.

                  B.  Exercise.  This Warrant shall be exercised by surrender to
the Company, at its principal office, of this Warrant Certificate, together with
the Purchase Form attached hereto duly completed and signed, and upon payment to
the Company of the Exercise  Price for the number of shares of Warrant  Stock in
respect  of which  this  Warrant is then  exercised.  Payment  of the  aggregate
Exercise Price shall be made in cash or by certified or official bank check.

                  C. Warrant  Certificate.  Subject to Section III hereof,  upon
such surrender of this Warrant  Certificate and payment of the Exercise Price as
aforesaid,  the  Company  shall issue and cause to be  delivered  to or upon the
written order of the Warrantholder,  by the second trading day after exercise, a
certificate  or  certificates  for the number of full shares of Warrant Stock so
purchased upon the exercise of such Warrant,  together with cash, as provided in
Section  VI  hereof,  in  respect  of any  fractional  shares of  Warrant  Stock
otherwise  issuable  upon  such  surrender.  Such  certificate  or  certificates
representing  the  Warrant  Stock  shall be deemed to have been  issued  and any
person so designated to be named therein shall be deemed to have become a holder
of  record of such  shares of  Warrant  Stock as of the date of  receipt  by the
Company  of this  Warrant  Certificate  and  payment  of the  Exercise  Price as
aforesaid;  provided, however, that if, at the date of surrender of this Warrant
Certificate and payment of the Exercise Price, the transfer books

                                Page 15 of 46



for the Warrant Stock or other class of stock purchasable upon the exercise of
this Warrant shall be closed, the certificate or certificates for the shares of
Warrant Stock in respect of which this Warrant is then exercised shall be deemed
issuable as of the date on which such books shall next be opened (whether before
or after the Termination Date) and until such date the Company shall be under no
duty to deliver any certificate  for such  shares of Warrant  Stock;  provided
further, however, that the transfer books of record, unless otherwise required

by law, shall not be closed at any one time for a period longer than twenty (20)
days. The rights of purchase represented by this Warrant shall be  exercisable,
at the election of the Warrantholder, either in full or from time to time in
part, and, in the event that this Warrant is exercised in respect of fewer than
all of the shares of Warrant Stock purchasable on such exercise at any time
prior to the Termination Date, a new Warrant Certificate evidencing the
remaining Warrant or Warrants will be issued, and the Company shall deliver the
new Warrant Certificate or Certificates  pursuant to the provisions of this
Section.

SECTION 7.  PAYMENT OF TAXES

             The Company will pay all documentary stamp taxes, if any,
attributable to the initial issuance of the shares of Warrant Stock upon the
exercise of this Warrant; provided, however, that the Warrantholder shall pay
any tax or taxes which may be payable in respect of any transfer involved in the
issue or delivery of Warrant  Certificates or the certificates for the shares of
Warrant Stock in a name other than that of the Warrantholder in respect of which
this Warrant or shares of Warrant Stock are issued.

SECTION 8.  MUTILATED OR MISSING WARRANT CERTIFICATES

             In case this Warrant Certificate shall be mutilated, lost,
stolen or destroyed, the Company shall, at the request of the Warrantholder,
issue and deliver, in exchange and substitution for and upon cancellation of
this certificate if mutilated, or in lieu of and in substitution for this
certificate if lost, stolen or destroyed, a new Warrant Certificate of like
tenor and representing an equivalent right or interest, but only upon receipt of
evidence reasonably satisfactory to the Company of such loss, theft or
destruction of this Warrant Certificate and indemnity, if requested, also
reasonably satisfactory to the Company.

SECTION 9.  RESERVATION OF SHARES OF WARRANT STOCK

             There has been reserved, and the Company shall at all times
keep reserved so long as this Warrant remains outstanding, out of its authorized
Common  Stock a number of shares of Common Stock  sufficient  to provide for the
exercise of the rights of purchase  represented  by this  Warrant.  The transfer
agent for the Common Stock and every subsequent transfer agent for any shares of
the Company's capital stock issuable upon the exercise of this

                                Page 16 of 46



Warrant will be irrevocably authorized and directed at all times to reserve such
number of authorized shares as shall be requisite for such purpose.

SECTION 10.  FRACTIONAL SHARES

             No fractional shares or scrip representing fractional shares
shall be issued upon the exercise of this Warrant. With respect to any fraction
of a share called for upon the exercise of this  Warrant, the Company shall pay
to the Warrantholder an amount in cash equal to such fraction multiplied by the

Exercise Price then in effect.

SECTION 11.  ADJUSTMENTS OF EXERCISE PRICE AND NUMBER OF SHARES

                  A.   Computation of Adjusted  Exercise Price.  Except as
hereinafter provided, in case the Company shall at any time after the date
hereof (i) issue or sell any shares of Common Stock (except in those instances
referred to in subsection F of this Section VII), including shares held in the
Company's treasury and shares issued upon the exercise of any option, rights or
warrants (with the exception of this Warrant and any other options and warrants
outstanding on the date hereof, and without duplicating any adjustments pursuant
to clause (ii) below) and shares issued upon the direct or indirect conversion
or exchange of securities for shares of Common Stock (with the exception of the
Company's Series A Cumulative Convertible Preferred Stock and Series B
Convertible Preferred Stock (collectively, the "Preferred Stock"), and without
duplicating any adjustments pursuant to clause (ii) below) for a consideration
per share less than the Market Price (as hereinafter defined) on the trading day
immediately prior to the date of issuance or sale of such share or without
consideration, or (ii) issue any rights, options or warrants to subscribe for or
purchase or otherwise acquire Common Stock (the "Option Securities") or any
evidences of indebtedness, shares of stock or other securities (other than the
Preferred Stock) which are convertible into or exchangeable, with or without
payment of consideration, for shares of Common Stock (the "Convertible
Securities"), whether or not the right to exercise such Option Securities or to
convert or exchange such Convertible Securities is immediately exercisable or is
conditioned upon the passage of time, the occurrence or  nonoccurrence of some
other event, or both, for a consideration per share of Common Stock (calculated
in accordance with subsections  A(iii) and A(iv) of this Article VII) less than
the Market Price on the trading day immediately prior to the date of issuance of
such Option Securities or Convertible Securities, then forthwith upon such
issuance or sale the Exercise Price shall (until another such issuance or sale)
be reduced to a price (calculated to the nearest full cent) determined by
multiplying the Exercise Price immediately prior to such issuance or sale by a
fraction, the numerator of which is an amount equal to the sum of (X) the total
number of shares of Common Stock outstanding immediately prior to such issuance
or sale, multiplied by the Market Price in effect immediately prior to such
issuance or sale, plus (Y) the

                                Page 17 of 46



aggregate of the amount of all consideration, if any, received by the Company
upon such issuance or sale, and the  denominator of which is the Market Price in
effect immediately prior to such issuance or sale multiplied by the total number
of shares of Common Stock  outstanding  immediately after such issuance or sale;
provided,  however,  that in no event  shall  the  Exercise  Price  be  adjusted
pursuant to this  computation  to an amount in excess of the  Exercise  Price in
effect  immediately  prior  to  such  computation,  except  in  the  case  of  a
combination of outstanding  shares of Common Stock,  as provided by subsection B
of this Section VII.

                  For the purposes of any  computation  to be made in accordance
with this subsection A, the following provisions shall be applicable:


                           1.  In case of the issuance or sale of shares of
Common Stock for a consideration  part or all of which shall be cash, the amount
of the cash consideration  therefor shall be deemed to be the amount of the cash
received  by the  Company  for such  shares  (or,  if shares are  offered by the
Company for subscription, the subscription price, or, if sold to underwriters or
dealers the public offering price) before  deducting  therefrom any compensation
paid or  discount  allowed  in the sale,  underwriting  or  purchase  thereof by
underwriters or dealers or others performing  similar services,  or any expenses
incurred in connection therewith.

                           2.  In case of the issuance or sale (otherwise
than as a dividend or other  distribution on any stock of the Company) of shares
of Common  Stock for a  consideration  part or all of which  shall be other than
cash, the amount of the  consideration  therefor other than cash shall be deemed
to be the value of such  consideration  as determined in good faith by the Board
of Directors of the Company.

                           3.  In case of the issuance of Convertible
Securities (other than the Convertible  Securities described in (iv) below), the
aggregate   consideration   received   therefor   shall  be  deemed  to  be  the
consideration,  if  any,  received  by the  Company  for  the  issuance  of such
Convertible Securities, plus the additional minimum consideration, if any, to be
received by the Company upon the conversion or exchange thereof.

                           4.  In the case of the issuance of Option
Securities,  the aggregate consideration received therefor shall be deemed to be
the  consideration,  if any,  received by the  Company for the  issuance of such
Option  Securities,  plus the additional  minimum  consideration,  if any, to be
received by the Company upon the exercise thereof.

                           5.  Shares of Common Stock issuable by way of
dividend or other  distribution  on any stock of the Company  shall be deemed to
have been issued immediately after the opening of business on the date following
the record date for the

                                Page 18 of 46





determination  of  stockholders  entitled  to  receive  such  dividend  or other
distribution and shall be deemed to have been issued without consideration.

                           6.  The reclassification of securities of the
Company,  other than shares of Common Stock into securities  including shares of
Common  Stock,  shall be deemed to involve  the  issuance  of such  shares for a
consideration  other than cash immediately prior to the close of business on the
date fixed for the  determination  of security  holders entitled to receive such
shares,  and the value of the  consideration  allocable  to such shares shall be
determined as provided in subsection (ii) of this subsection A.

                           7.  The number of shares of Common Stock at any

one time  outstanding  shall  include the  aggregate  number of shares issued or
issuable  (subject to readjustment  upon the actual  issuance  thereof) upon the
exercise of  outstanding  options,  rights,  warrants and upon the conversion or
exchange of outstanding convertible or exchangeable securities.

                  "Market  Price," as of any date,  (i) means the average of the
last reported sale prices for the shares of Common Stock as reported by National
Association of Securities  Dealers  Automated  Quotation  National Market System
("NASDAQ-NMS")  for the five  consecutive  trading days ending on such date,  or
(ii) if the  NASDAQ-NMS  is not the principal  trading  market for the shares of
Common  Stock,  the average of the last  reported  sale prices on the  principal
trading  market for the Common Stock during the same period,  or (iii) if market
value cannot be calculated as of such date on any of the  foregoing  bases,  the
Market Price shall be the average fair market value as reasonably  determined in
good faith by the Board of Directors of the Company.

                  B.  Subdivision and Combination.  In case the Company
shall at any time subdivide or combine the outstanding shares of
Common Stock, the Exercise Price shall forthwith be
proportionately decreased in the case of subdivision or increased
in case of combination.

                  C. Adjustment in Number of Shares. Upon each adjustment of the
Exercise  Price  pursuant to the  provisions  of this Section VII, the number of
shares of Warrant  Stock  issuable  upon the exercise of this  Warrant  shall be
adjusted to the nearest full share by multiplying a number equal to the Exercise
Price in effect  immediately prior to such adjustment by the number of shares of
Warrant Stock issuable upon exercise of this Warrant  immediately  prior to such
adjustment and dividing the product so obtained by the adjusted Exercise Price.

                  D.  Reclassification, Consolidation, Merger, etc.  In case of 
any reclassification or change of the outstanding shares of Common Stock (other
than a change in par value to no par value, or from no par value to par value,
or as a result of a subdivision or combination), or in the case of any
consolidation

                                Page 19 of 46





of the Company with, or merger of the Company into,  another  corporation (other
than a consolidation or merger in which the Company is the surviving corporation
and which does not result in any  reclassification  or change of the outstanding
shares  of  Common  Stock,  except a  change  as a result  of a  subdivision  or
combination of such shares or a change in par value,  as  aforesaid),  or in the
case of a sale or conveyance to another  corporation of all or substantially all
of the property of the Company,  the  Warrantholder  shall  thereafter  have the
right to  purchase  upon the  exercise  of this  Warrant  the kind and number of
shares  of  stock  and  other  securities  and  property  receivable  upon  such
reclassification,  change,  consolidation,  merger, sale or conveyance as if the
Warrantholder  were the owner of the shares of  Warrant  Stock  underlying  this
Warrant  immediately  prior to any such events at the  Exercise  Price in effect

immediately  prior  to  the  record  date  for  such  reclassification,  change,
consolidation, merger, sale or conveyance as if such Warrantholder had exercised
this Warrant.

                  E. Special  Adjustment.  If the purchase price provided for in
any Option Securities,  the additional  consideration,  if any, payable upon the
conversion  or exchange of any  Convertible  Securities or the rate at which any
Convertible  Securities are convertible  into or  exchangeable  for Common Stock
shall change, or if any Option Securities or Convertible Securities terminate in
whole or in part without being exercised,  converted or exchanged,  the Exercise
Price in effect at the time of such event shall  forthwith  be  readjusted.  The
Exercise  Price shall be adjusted to that amount which would have been in effect
at such time had such Option Securities or Convertible Securities outstanding at
such  time  initially  been  granted,  issued  or sold  and the  Exercise  Price
initially  adjusted as provided in subsection A of this Article VII, except that
the minimum  amount of  additional  consideration  payable and the total maximum
number of shares issuable shall be determined  after giving effect to such event
(and any prior event or events).

                  F.  No Adjustment of Exercise Price in Certain Cases.
No adjustment of the Exercise Price shall be made:

                           1.  Upon the issuance or sale of this Warrant or
the shares of Warrant Stock  issuable upon the exercise of this Warrant,  or the
issuance  or sale of the  Preferred  Stock,  or upon the  issuance  of shares of
Common Stock in connection  with the conversion of such Preferred  Stock, or the
issuance of shares of Common Stock pursuant to Section 2(c) of the  Registration
Rights  Agreement  of even date  herewith by and among the Company and the Buyer
and pursuant to Section 2(b) of the Certificate of Designations, Preferences and
Rights of Series B Convertible Preferred Stock of the Company;

                           2.  Upon the issuance of options, or shares upon
the exercise thereof, pursuant to the Company's Non-Qualified
Stock Option Plan, or any amendment or successor plan thereto;


                                Page 20 of 46





                           3.  If the amount of said adjustment shall be less
than one  cent  ($.01)  per  share;  provided,  however,  that in such  case any
adjustment  that would  otherwise  be required  then to be made shall be carried
forward and shall be made at the time of and  together  with any  adjustment  so
carried forward, shall amount to at least one cent ($.01) per Share;

                           4.  Upon the issuance or sale of shares of Common
Stock or securities  which are exercisable or convertible  into shares of Common
Stock to employees  of the Company or its  affiliates,  under an Employee  Stock
Purchase Plan;

                           5.  Upon the issuance of any Option Securities or

the  issuance of shares of Common Stock upon the  exercise  thereof,  where such
Option Security was issued for a  consideration  price per share of Common Stock
initially  deliverable upon exercise of such Option Security equal to or greater
than the Market  Price in effect  immediately  prior to the  issuance or sale of
such Option Security;

                           6.  Upon the issuance of Convertible Securities
where the  conversion  price is equal to or  greater  than the  Market  Price in
effect immediately prior to the issuance of such Convertible Securities;

                           7.  Upon the issuance of Common Stock to non-
management directors of the Company in an amount up to Fourteen Thousand Dollars
($14,000) per such director per year, based upon such method of valuation as may
be  established  from time to time by the  Company's  Board of  Directors in its
reasonable discretion; or

                           8.  Upon the issuance of an aggregate of up to
Three  Million  Dollars  ($3,000,000)  of Common Stock or  securities  which are
exercisable or  convertible  into Common Stock at a discount to the Market Price
as of the date of such issuance that does not exceed twenty percent (20%).

SECTION 12.  NOTICES TO WARRANTHOLDERS

                  So long as this Warrant shall be outstanding  and  unexercised
(a) if the  Company  shall pay any  dividend or make any  distribution  upon the
Common  Stock or (b) if the Company  shall offer to the holders of Common  Stock
for  subscription  or  purchase  by them any shares of stock of any class or any
other   rights  or  (c)  if  any   capital   reorganization   of  the   Company,
reclassification of the capital stock of the Company, consolidation or merger of
the Company with or into  another  corporation,  sale,  lease or transfer of the
Company  to  another  corporation,  or  voluntary  or  involuntary  dissolution,
liquidation  or winding up of the Company  shall be effected,  then, in any such
case, the Company shall cause to be delivered to the Warrantholder, at least ten
(10) days prior to the date specified in (i) or (ii) below,  as the case may be,
a notice  containing a brief  description of the proposed action and stating the
date on

                                Page 21 of 46




which  (i) a  record  is to be  taken  for  the  purpose  of  such  dividend  or
distribution,  or (ii)  such  reclassification,  reorganization,  consolidation,
merger,  conveyance,  lease,  dissolution,  liquidation or winding up is to take
place and the date,  if any, as of which the  holders of Common  Stock of record
shall be entitled to exchange  their  shares of Common Stock for  securities  or
other  property   deliverable   upon  such   reclassification,   reorganization,
consolidation,  merger,  conveyance,  dissolution,  liquidation  or winding  up.
Additionally,  so long as this Warrant shall be outstanding and unexercised,  if
the Company shall make any adjustment to the Exercise  Price,  the Company shall
cause to be delivered to the  Warrantholder,  within  twenty (20) days after the
date of such adjustment,  a notice  containing a description of the calculations
pertaining to such  adjustment  and stating the date on which the  adjustment to

the Exercise Price became effective.

SECTION 13.  DELIVERY OF NOTICES

                  Any notice  pursuant to this  Warrant by the Company or by the
Warrantholder shall be in writing and shall be deemed to have been duly given if
delivered or mailed  certified  mail,  return receipt  requested,  (a) if to the
Company, to it at 20 Kingsbridge Road, Piscataway,  New Jersey 08854, Attention:
Corporate  Secretary and (b) if to the  Warrantholder,  to it at the address set
forth on the  signature  pace  hereto.  Each party  hereto may from time to time
change the address to which such  party's  notices are to be delivered or mailed
hereunder by notice in accordance herewith to the other party.

SECTION 14.  SUCCESSORS

                  All the covenants and  provisions of this  Agreement by or for
the  benefit  of the  Company or the  Warrantholder  shall bind and inure to the
benefit of their respective successors and assigns hereunder.

SECTION 15.  APPLICABLE LAW

                  This Warrant  shall be deemed to be a contract  made under the
laws of the State of Delaware  applicable to agreements made and to be performed
entirely in Delaware and for all purposes shall be construed in accordance  with
the internal  laws of Delaware  without  giving  effect to the conflicts of laws
principles thereof.

SECTION 16.  BENEFITS OF THIS AGREEMENT

                  Nothing  in this  Warrant  shall be  construed  to give to any
person or corporation  other than the Company and the Warrantholder any legal or
equitable  right,  remedy or claim under this Warrant and this Warrant  shall be
for the sole and exclusive benefit of the Company and the Warrantholder.


                                Page 22 of 46




                  IN WITNESS WHEREOF, the parties hereto have executed this
Warrant Certificate or caused this Warrant Certificate to be duly executed as of
the 7th day of February, 1996.


                                           ENZON, INC.


                                           By: /s/ Peter G. Tombros
                                              -----------------------------
                                              Name:  Peter G. Tombros
                                              Title: President and CEO



                                           GFL PERFORMANCE FUND LTD.


                                           By: /s/ A.P. de Groot
                                              ------------------------------
                                              Name:  A.P. de Groot
                                              Title: President

                                           Address of Warrantholder:

                                           Genesee Fund Limited
                                           CITCO Building
                                           Wickhams Cay
                                           P.O. Box 662
                                           Road Town, Tortola
                                           British Virgin Islands

                                           Administrator
                                           Curacao International Trust Co. N.V.
                                           Kaya Flamboyan 9
                                           P.O. Box 812
                                           Curacao, Netherland Antilles


                                Page 23 of 46






                                PURCHASE FORM


                  The  undersigned  hereby  irrevocably  elects to exercise  the
Warrant  represented  by this Warrant  Certificate  to the extent of ___________
shares of Common Stock,  par value $.01 per share,  of Enzon,  Inc.,  and hereby
makes payment of  $___________________  in payment of the actual  exercise price
thereof.







                                      [-----------------------------]


                                      By:___________________________
                                         Name:
                                         Title:



                                         Employer Taxpayer
                                              Identification Number:


                                         Address for delivery of Stock
                                         Certificate:


                                Page 24 of 46






                               ASSIGNMENT FORM



                  FOR  VALUED  RECEIVED,  ______________________________  hereby
sells,    assigns    and    transfers    unto    ____________________    address
________________________  the right to purchase Common Stock, par value $.01 per
share, of Enzon, Inc.,  represented by this Warrant Certificate to the extent of
_____________  shares as to which  such  right is  exercisable  and does  hereby
irrevocably constitute and appoint _______________________, to transfer the same
on the books of the Company with full power of substitution in the premises.



- -------------------------
Signature


Dated:  _____________, _____

                                              Notice:  The signature of this
                                              assignment must correspond with
                                              the name as it appears upon the
                                              face of this Warrant Certificate 
                                              in every particular, without 
                                              alteration or enlargement or any  
                                              change whatever.


SIGNATURE GUARANTEED:



- ----------------------------

                                Page 25 of 46





                                CROSS RECEIPT


                  In connection with the closing of the transaction provided for
in the Securities  Purchase  Agreement  dated as of January 31, 1996 (the "Stock
Purchase  Agreement") among Enzon, Inc. (the "Company") and the undersigned (the
"Buyer"), the Company and the Buyer acknowledge as follows:

                  1.  The Buyer does hereby acknowledge receipt from the 
Company of Certificate No. 1, representing 40,000 shares of the Company's Common
Stock, $.01 par value (the "Shares"), of Warrant No. 1 for 364,962 shares of
Common Stock, and the Warrant No. 2 for 273,723 shares of Common Stock.

                  2. The Company does hereby acknowledge receipt from the Buyer,
by wire transfer of immediately available funds, of the sum of $4,000,000,
representing payment in full of the purchase price for the Shares, said funds
having been transferred to the Company's account in accordance with the
Company's instructions.

                  IN WITNESS WHEREOF, the parties have executed this Cross
Receipt this 7th day of February 1996.



                                      ENZON, INC.


                                      By: /s/ Kenneth J. Zuerblis
                                         ---------------------------
                                         Name:   Kenneth J. Zuerblis
                                         Title:  Vice President,
                                                 Finance and Chief
                                                 Financial Officer


                                     GFL ADVANTAGE FUND LTD.
                                     GFL PERFORMANCE FUND LTD.


                                     By: /s/ Gena M. Seaberg
                                        -----------------------------
                                        Name:   Gena M. Seaberg
                                        Title:  Office Manager

                                Page 26 of 46





                                  EXHIBIT 3




         AMENDED AND RESTATED WARRANT  ("WARRANT") TO PURCHASE 200,000 SHARES OF
COMMON  STOCK.  VOID AFTER 5:00 P.M.  NEW JERSEY TIME,  ON MARCH 15, 2001.  THIS
WARRANT AND THE SHARES OF COMMON STOCK  ISSUABLE  UPON THE EXERCISE  HEREOF HAVE
BEEN AND WILL BE ISSUED IN TRANSACTIONS WHICH HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER ANY STATE SECURITIES OR
BLUE SKY  LAWS.  THIS  WARRANT  AND SUCH  SHARES  MAY NOT BE SOLD,  TRANSFERRED,
PLEDGED,  HYPOTHECATED  OR OTHERWISE  DISPOSED  OF, IN WHOLE OR IN PART,  IN THE
ABSENCE OF AN  EFFECTIVE  REGISTRATION  STATEMENT  UNDER THE ACT AND  APPLICABLE
STATE  LAW,  OR AN  OPINION  OF  COUNSEL  ACCEPTABLE  TO THE  COMPANY  THAT SUCH
REGISTRATION IS NOT REQUIRED.



NO.______________________                                         200,000 SHARES




                                 ENZON, INC.

         This certifies that, for value received, GFL Performance Fund Ltd., the
registered  holder  hereof,  or assigns  (the  "Warrantholder")  is  entitled to
purchase from Enzon, Inc., a Delaware  corporation (the "Company"),  at any time
on and after the date hereof and before 5:00 p.m., New Jersey time, on March 15,
2001 (the  "Termination  Date"),  at the purchase price of $5.625 per share (the
"Exercise  Price"),  the  number of shares of Common  Stock,  par value $.01 per
share (the  "Common  Stock"),  of the  Company  set forth  above  (the  "Warrant
Stock").  The number of shares of Warrant Stock,  the  Termination  Date and the
Exercise  Price per share of this Warrant  shall be subject to  adjustment  from
time to time as set forth below.

SECTION I.  TRANSFER OR EXCHANGE OF WARRANT

         The Company shall be entitled to treat the  Warrantholder  as the owner
in fact  hereof  for all  purposes  and  shall  not be  bound to  recognize  any
equitable or other claim to or interest in this Warrant on the part of any other
person.  This Warrant  shall be  transferable  only on the books of the Company,
maintained at its principal office,  upon delivery of this Warrant duly endorsed
by the Warrantholder or by its duly authorized  attorney or  representative,  or
accompanied  by proper  evidence  of  succession,  assignment  or  authority  to
transfer.  Upon any  registration  of transfer,  the Company shall deliver a new
Warrant or Certificates to the persons entitled thereto.


                                Page 27 of 46






SECTION II.  TERM OF WARRANT; EXERCISE OF WARRANTS

         A.  Termination.  The Company may, in its sole discretion,
extend the Termination Date with respect to the exercise of this Warrant upon
notice to the Warrantholder.  As used herein, "Termination Date" shall be deemed
to include any such extensions.

         B.  Exercise.  This  Warrant  shall be  exercised  by  surrender to the
Company,  at its principal office,  of this Warrant,  together with the Purchase
Form attached hereto duly completed and signed,  and upon payment to the Company
of the  Exercise  Price for the number of shares of Warrant  Stock in respect of
which this Warrant is then  exercised.  Payment of the aggregate  Exercise Price
shall be made in cash or by certified or official bank check.

         C. Warrant.  Subject to Section III hereof, upon such surrender of this
Warrant and payment of the Exercise Price as aforesaid,  the Company shall issue
and cause to be delivered to or upon the written order of the Warrantholder,  by
the second trading day after  exercise,  a certificate or  certificates  for the
number of full shares of Warrant  Stock so  purchased  upon the exercise of such
Warrant, together with cash, as provided in Section VI hereof, in respect of any
fractional shares of Warrant Stock other-wise issuable upon such surrender. Such
certificate or  certificates  representing  the Warrant Stock shall be deemed to
have been  issued  and any person so  designated  to be named  therein  shall be
deemed to have become a holder of record of such  shares of Warrant  Stock as of
the date of receipt by the Company of this  Warrant and payment of the  Exercise
Price as aforesaid; provided, however, that if, at the date of surrender of this
Warrant and payment of the Exercise  Price,  the transfer  books for the Warrant
Stock or other class of stock  purchasable  upon the  exercise  of this  Warrant
shall be closed, the certificate or certificates for the shares of Warrant Stock
in respect of which this Warrant is then exercised  shall be deemed  issuable as
of the date on which such books  shall next be opened  (whether  before or after
the Termination  Date) and until such date the Company shall be under no duty to
deliver any  certificate  for such shares of Warrant  Stock;  provided  further,
however,  that the transfer books of record,  unless otherwise  required by law,
shall not be closed at any one time for a period  longer  than twenty (20) days.
The rights of purchase represented by this Warrant shall be exercisable,  at the
election of the Warrantholder, either in full or from time to time in part, and,
in the event that this  Warrant is exercised in respect of fewer than all of the
shares of Warrant  Stock  purchasable  on such exercise at any time prior to the
Termination  Date, a new Warrant  evidencing  the remaining  Warrant or Warrants
will be issued,  and the Company shall  deliver the new Warrant or  Certificates
pursuant to the provisions of this Section.

SECTION III.  PAYMENT OF TAXES

         The Company will pay all documentary stamp taxes, if any,  attributable
to the initial issuance of the shares of Warrant Stock upon the exercise of this
Warrant; provided, however, that the


                                Page 28 of 46





Warrantholder  shall pay any tax or taxes which may be payable in respect of any
transfer  involved in the issue or delivery of Warrants or the  certificates for
the shares of Warrant  Stock in a name other than that of the  Warrantholder  in
respect of which this Warrant or shares of Warrant Stock are issued.

SECTION IV.  MUTILATED OR MISSING WARRANTS

         In case this Warrant shall be mutilated, lost, stolen or destroyed, the
Company  shall,  at the  request of the  Warrantholder,  issue and  deliver,  in
exchange and  substitution  for and upon  cancellation  of this  certificate  if
mutilated,  or in lieu of and in  substitution  for  this  certificate  if lost,
stolen or destroyed,  a new Warrant of like tenor and representing an equivalent
right or interest, but only upon receipt of evidence reasonably  satisfactory to
the Company of such loss, theft or destruction of this Warrant and indemnity, if
requested, also reasonably satisfactory to the Company.

SECTION V.  RESERVATION OF SHARES OF WARRANT STOCK

         There  has been  reserved,  and the  Company  shall at all  times  keep
reserved so long as this  Warrant  remains  outstanding,  out of its  authorized
Common  Stock a number of shares of Common Stock  sufficient  to provide for the
exercise of the rights of purchase  represented  by this  Warrant.  The transfer
agent for the Common Stock and every subsequent transfer agent for any shares of
the Company's  capital stock  issuable upon the exercise of this Warrant will be
irrevocably  authorized  and  directed  at all times to reserve  such  number of
authorized shares as shall be requisite for such purpose.

SECTION VI.  FRACTIONAL SHARES

         No fractional shares or scrip  representing  fractional shares shall be
issued upon the  exercise of this  Warrant.  With  respect to any  fraction of a
share called for upon the exercise of this Warrant, the Company shall pay to the
Warrantholder  an  amount  in cash  equal  to such  fraction  multiplied  by the
Exercise Price then in effect.

SECTION VII.  ADJUSTMENTS OF EXERCISE PRICE AND NUMBER OF SHARES

         A.  Computation  of  Adjusted  Exercise  Price.  Except as  hereinafter
provided,  in case the Company shall at any time after the date hereof (i) issue
or sell any shares of Common  Stock  (except in those  instances  referred to in
subsection  F of this  Section  VII),  including  shares  held in the  Company's
treasury and shares  issued upon the exercise of any option,  rights or warrants
(with  the  exception  of  this  Warrant  and any  other  options  and  warrants
outstanding on the date hereof, and without duplicating any adjustments pursuant
to clause (ii) below) and shares  issued upon the direct or indirect  conversion
or exchange of securities  for shares of Common Stock (with the exception of the
Company's Series A Cumulative Convertible Preferred Stock, Series B


                                Page 29 of 46



Convertible   Preferred   Stock  and  Series  D  Convertible   Preferred   Stock
(collectively,  the "Preferred Stock"),  and without duplicating any adjustments
pursuant  to clause  (ii)  below)  for a  consideration  per share less than the
Market Price (as hereinafter  defined) on the trading day  immediately  prior to
the date of  issuance  or sale of such share or without  consideration,  or (ii)
issue any rights,  options or warrants to subscribe for or purchase or otherwise
acquire Common Stock (the "Option Securities") or any evidences of indebtedness,
shares of stock or other  securities  (other than the Preferred Stock) which are
convertible into or exchangeable, with or without payment of consideration,  for
shares of Common Stock (the "Convertible Securities"),  whether or not the right
to exercise such Option  Securities  or to convert or exchange such  Convertible
Securities is  immediately  exercisable  or is  conditioned  upon the passage of
time,  the  occurrence or  non-occurrence  of some other event,  or both,  for a
consideration   per  share  of  Common  Stock  (calculated  in  accordance  with
subsections  A(iii) and A(iv) of this Article VII) less than the Market Price on
the  trading  day  immediately  prior to the  date of  issuance  of such  Option
Securities or Convertible Securities,  then forthwith upon such issuance or sale
the Exercise  Price shall (until  another such issuance or sale) be reduced to a
price  (calculated  to the nearest  full cent)  determined  by  multiplying  the
Exercise  Price  immediately  prior to such issuance or sale by a fraction,  the
numerator  of which is an  amount  equal to the sum of (X) the  total  number of
shares of Common Stock  outstanding  immediately prior to such issuance or sale,
multiplied by the Market Price in effect  immediately  prior to such issuance or
sale,  plus  (Y) the  aggregate  of the  amount  of all  consideration,  if any,
received by the Company upon such issuance or sale, and the denominator of which
is the  Market  Price  in  effect  immediately  prior to such  issuance  or sale
multiplied by the total number of shares of Common Stock outstanding immediately
after such  issuance  or sale;  provided,  however,  that in no event  shall the
Exercise Price be adjusted  pursuant to this  computation to an amount in excess
of the Exercise Price in effect immediately prior to such computation, except in
the case of a combination of outstanding  shares of Common Stock, as provided by
subsection B of this Section VII.

         For the purposes of any  computation to be made in accordance with this
subsection A, the following provisions shall be applicable:

                  (i) In case of the  issuance or sale of shares of Common Stock
for a  consideration  part or all of which shall be cash, the amount of the cash
consideration  therefor shall be deemed to be the amount of the cash received by
the  Company  for such  shares  (or,  if shares are  offered by the  Company for
subscription, the subscription price, or, if sold to underwriters or dealers the
public  offering  price) before  deducting  therefrom any  compensation  paid or
discount  allowed in the sale,  underwriting or purchase thereof by underwriters
or dealers or others performing  similar  services,  or any expenses incurred in
connection therewith.


                                Page 30 of 46






                  (ii) In  case of the  issuance  or sale  (otherwise  than as a
dividend or other  distribution on any stock of the Company) of shares of Common
Stock for a  consideration  part or all of which  shall be other than cash,  the
amount of the  consideration  therefor other than cash shall be deemed to be the
value  of such  consideration  as  determined  in good  faith  by the  Board  of
Directors of the Company.

                  (iii) In case of the issuance of Convertible Securities (other
than  the  Convertible  Securities  described  in  (iv)  below),  the  aggregate
consideration received therefor shall be deemed to be the consideration, if any,
received by the Company for the issuance of such  Convertible  Securities,  plus
the additional minimum consideration, if any, to be received by the Company upon
the conversion or exchange thereof.

                  (iv) In the case of the  issuance  of Option  Securities,  the
aggregate   consideration   received   therefor   shall  be  deemed  to  be  the
consideration,  if any,  received by the Company for the issuance of such Option
Securities, plus the additional minimum consideration, if any, to be received by
the Company upon the exercise thereof.

                  (v) Shares of Common  Stock  issuable  by way of  dividend  or
other  distribution  on any  stock of the  Company  shall be deemed to have been
issued  immediately  after the  opening of business  on the date  following  the
record date for the  determination  of  stockholders  entitled  to receive  such
dividend or other  distribution  and shall be deemed to have been issued without
consideration.

                  (vi) The reclassification of securities of the Company,  other
than shares of Common Stock into  securities  including  shares of Common Stock,
shall be deemed to involve the issuance of such shares for a consideration other
than cash  immediately  prior to the close of business on the date fixed for the
determination of security holders entitled to receive such shares, and the value
of the consideration allocable to such shares shall be determined as provided in
subsection (ii) of this subsection A.

                  (vii) The  number  of  shares of Common  Stock at any one time
outstanding  shall  include the  aggregate  number of shares  issued or issuable
(subject to readjustment  upon the actual issuance thereof) upon the exercise of
outstanding  options,  rights,  warrants and upon the  conversion or exchange of
outstanding convertible or exchangeable securities.

         "Market  Price,"  as of any date,  (i) means  the  average  of the last
reported  sale  prices for the shares of Common  Stock as  reported  by National
Association of Securities  Dealers  Automated  Quotation  National Market System
("NASDAQ-NMS")  for five consecutive  trading days, or (ii) if the NASDAQ-NMS is
not the principal  trading market for the shares of Common Stock, the average of
the last  reported sale prices on the  principal  trading  market for the Common
Stock during the same period, or (iii) if

                                Page 31 of 46






market value cannot be calculated as of such date on any of the foregoing bases,
the Market Price shall be the average fair market value as reasonably determined
in good faith by the Board of Directors of the Company.

         B.  Subdivision and Combination.  In case the Company shall at
any time subdivide or combine the outstanding shares of Common Stock, the
Exercise Price shall forthwith be proportionately decreased in the case of
subdivision or increased in case of combination.

         C. Adjustment in Number of Shares. Upon each adjustment of the Exercise
Price  pursuant to the  provisions  of this Section VII, the number of shares of
Warrant  Stock  issuable  upon the exercise of this Warrant shall be adjusted to
the nearest full share by  multiplying  a number equal to the Exercise  Price in
effect  immediately  prior to such adjustment by the number of shares of Warrant
Stock  issuable  upon  exercise  of  this  Warrant  immediately  prior  to  such
adjustment and dividing the product so obtained by the adjusted Exercise Price.

         D.  Reclassification,  Consolidation,  Merger,  etc.  In  case  of  any
reclassification or change of the outstanding shares of Common Stock (other than
a change in par value to no par value,  or from no par value to par value, or as
a result of a subdivision or combination),  or in the case of any  consolidation
of the Company with, or merger of the Company into,  another  corporation (other
than a consolidation or merger in which the Company is the surviving corporation
and which does not result in any  reclassification  or change of the outstanding
shares  of  Common  Stock,  except a  change  as a result  of a  subdivision  or
combination of such shares or a change in par value,  as  aforesaid),  or in the
case of a sale or conveyance to another  corporation of all or substantially all
of the property of the Company,  the  Warrantholder  shall  thereafter  have the
right to  purchase  upon the  exercise  of this  Warrant  the kind and number of
shares  of  stock  and  other  securities  and  property  receivable  upon  such
reclassification,  change,  consolidation,  merger, sale or conveyance as if the
Warrantholder  were the owner of the shares of  Warrant  Stock  underlying  this
Warrant  immediately  prior to any such events at the  Exercise  Price in effect
immediately  prior  to  the  record  date  for  such  reclassification,  change,
consolidation, merger, sale or conveyance as if such Warrantholder had exercised
this Warrant.

         E. Special Adjustment. If the purchase price provided for in any Option
Securities, the additional consideration, if any, payable upon the conversion or
exchange  of any  Convertible  Securities  or the rate at which any  Convertible
Securities are convertible  into or exchangeable  for Common Stock shall change,
or if any Option Securities or Convertible  Securities  terminate in whole or in
part without  being  exercised,  converted or exchanged,  the Exercise  Price in
effect at the time of such event shall  forthwith  be  readjusted.  The Exercise
Price shall be  adjusted to that amount  which would have been in effect at such
time had such Option Securities or Convertible Securities outstanding at such

                                Page 32 of 46





time  initially been granted,  issued or sold and the Exercise  Price  initially
adjusted  as provided  in  subsection  A of this  Article  VII,  except that the
minimum amount of additional  consideration payable and the total maximum number
of shares  issuable  shall be determined  after giving effect to such event (and
any prior event or events).

         F.  No Adjustment of Exercise Price in Certain Cases.  No adjustment 
of the Exercise Price shall be made:

                  (i) Upon the issuance or sale of this Warrant or the shares of
Warrant Stock  issuable upon the exercise of this Warrant or the Warrants  dated
February 7, 1996,  or the issuance or sale of the Preferred  Stock,  or upon the
issuance of shares of Common Stock in  connection  with the  conversion  of such
Preferred  Stock,  or the issuance of shares of Common Stock pursuant to Section
2(c) of the Registration Rights Agreements of even date herewith and January 31,
1996,  respectively,  by and among the  Company  and the Buyer and  pursuant  to
Section  2(b) of the  Certificate  of  Designations,  Preferences  and Rights of
Series B Convertible  Preferred  Stock and of the  Certificate of  Designations,
Preferences and Rights of Series D Convertible Preferred Stock of the Company;

                  (ii) Upon the issuance of options, or shares upon the exercise
thereof,  pursuant to the  Company's  Non-Qualified  Stock Option  Plan,  or any
amendment or successor plan thereto;

                  (iii) If the amount of said adjustment  shall be less than one
cent ($.01) per share; provided,  however, that in such case any adjustment that
would  otherwise be required then to be made shall be carried  forward and shall
be made at the time of and  together  with any  adjustment  so carried  forward,
shall amount to at least one cent ($.01) per Share;

                  (iv) Upon the  issuance  or sale of shares of Common  Stock or
securities  which are exercisable or convertible  into shares of Common Stock to
employees of the Company or its affiliates,  under an Employee Stock Purchase or
Option Plan;

                  (v) Upon the issuance of any Option Securities or the issuance
of shares of Common Stock upon the exercise thereof,  where such Option Security
option,  right or  warrant  was issued  for a  consideration  price per share of
Common Stock initially  deliverable  upon exercise of such Option Security equal
to or greater than the Market Price in effect  immediately prior to the issuance
or sale of such Option Security;

                  (vi) Upon the issuance of securities  convertible  into Common
Stock,  where the conversion  price is equal to or greater than the Market Price
in effect immediately prior to the issuance of such securities; or

                  (vii)  Upon the  issuance  of Common  Stock to  non-management
directors of the Company in an amount up to Twelve  Thousand  Dollars  ($12,000)
per such director per year, based upon

                                Page 33 of 46




such  method  of  valuation  as may be  established  from  time  to  time by the
Company's Board of Directors in its reasonable discretion.

SECTION VIII.  NOTICES TO WARRANTHOLDERS

         So long as this Warrant shall be outstanding and unexercised (a) if the
Company shall pay any dividend or make any distribution upon the Common Stock or
(b) if the Company  shall offer to the holders of Common Stock for  subscription
or purchase by them any shares of stock of any class or any other  rights or (c)
if any capital  reorganization of the Company,  reclassification  of the capital
stock of the  Company,  consolidation  or  merger  of the  Company  with or into
another  corporation,  sale,  lease  or  transfer  of  the  Company  to  another
corporation, or voluntary or involuntary dissolution,  liquidation or winding up
of the Company  shall be effected,  then,  in any such case,  the Company  shall
cause to be delivered to the Warrantholder,  at least ten (10) days prior to the
date specified in (i) or (ii) below,  as the case may be, a notice  containing a
brief  description  of the  proposed  action and stating the date on which (i) a
record is to be taken for the purpose of such dividend or distribution,  or (ii)
such reclassification, reorganization, consolidation, merger, conveyance, lease,
dissolution, liquidation or winding up is to take place and the date, if any, as
of which the  holders of Common  Stock of record  shall be  entitled to exchange
their shares of Common Stock for securities or other property  deliverable  upon
such  reclassification,   reorganization,   consolidation,  merger,  conveyance,
dissolution,  liquidation or winding up.  Additionally,  so long as this Warrant
shall be outstanding and  unexercised,  if the Company shall make any adjustment
to  the  Exercise  Price,  the  Company  shall  cause  to be  delivered  to  the
Warrantholder,  within  twenty  (20) days after the date of such  adjustment,  a
notice  containing  a  description  of  the  calculations   pertaining  to  such
adjustment  and stating the date on which the  adjustment to the Exercise  Price
became effective.

SECTION IX.  DELIVERY OF NOTICES

         Any  notice  pursuant  to  this  Warrant  by  the  Company  or  by  the
Warrantholder shall be in writing and shall be deemed to have been duly given if
delivered or mailed  certified  mail,  return receipt  requested,  (a) if to the
Company, to it at 20 Kingsbridge Road, Piscataway,  New Jersey 08854, Attention:
Corporate  Secretary  and (b) if to the  Warrantholder  to it at the address set
forth on the  signature  page  hereto.  Each party  hereto may from time to time
change the address to which such  party's  notices are to be delivered or mailed
hereunder by notice in accordance herewith to the other party.

SECTION X.  SUCCESSORS

         All  the  covenants  and  provisions  of this  Agreement  by or for the
benefit of the Company or the Warrantholder  shall bind and inure to the benefit
of their respective successors and assigns hereunder.

                                Page 34 of 46





SECTION XI.  APPLICABLE LAW

         This  Warrant  shall be deemed to be a contract  made under the laws of
the State of Delaware applicable to agreements made and to be performed entirely
in Delaware and for all  purposes  shall be  construed  in  accordance  with the
internal  laws of  Delaware  without  giving  effect  to the  conflicts  of laws
principles thereof.

SECTION XII.  BENEFITS OF THIS AGREEMENT

         Nothing in this  Warrant  shall be  construed  to give to any person or
corporation  other than the Company and the Warrantholder any legal or equitable
right, remedy or claim under this Warrant and this Warrant shall be for the sole
and exclusive benefit of the Company and the Warrantholder.

         IN WITNESS  WHEREOF,  the parties hereto have executed this Amended and
Restated Warrant or caused this Amended and Restated Warrant to be duly executed
as of the day and year first above written.

                                   ENZON, INC.


                                   By: /s/ Kenneth J. Zuerblis 
                                      ------------------------------  
                                   Name: Kenneth J. Zuerblis 
                                   Title: Vice President


                                   GFL PERFORMANCE FUND LTD.


                                   By: /s/
                                      ------------------------------ 
                                   Name:
                                   Title:

                                   Address of Warrantholder:

                                   GFL Performance Fund Ltd.
                                   c/o Clearwater Funds
                                   611 Druid Road East
                                   Suite 200
                                   Clearwater, Florida 34616


                                   Administrator
                                   Curacao International Trust Co. N.V.
                                   Kaya Flamboyan 9
                                   P.O. Box 812
                                   Curacao, Netherland Antilles

                                Page 35 of 46





                                PURCHASE FORM


         The  undersigned  hereby  irrevocably  elects to  exercise  the Warrant
represented  by this Warrant to the extent of _________  shares of Common Stock,
par  value  $.01 per  share,  of  Enzon,  Inc.,  and  hereby  makes  payment  of
$______________ in payment of the actual exercise price thereof.






                                [--------------------------]



                                By:__________________________
                                Name:
                                Title:



                                Employer Taxpayer
                                  Identification Number:



                                Address for delivery of Stock
                                Certificate:

                                Page 36 of 46





                               ASSIGNMENT FORM




         FOR VALUED RECEIVED,  _______________________ hereby sells, assigns and
transfers unto _____________________________ address ___________________________
the right to purchase Common Stock, par value $.01 per share,  of Enzon,  Inc., 
represented  by this Warrant to the extent of _______________ shares as to
which such right is  exercisable  and does  hereby irrevocably constitute and
appoint  __________________,  to transfer the same on the books of the Company
with full power of substitution in the premises.



- -------------------------
Signature


Dated: ___________, _____


                                        Notice:  The signature of this 
                                        assignment must correspond with
                                        the name as it appears upon the
                                        face of this Warrant in every
                                        particular, without alteration
                                        or enlargement or any change
                                        whatever.


SIGNATURE GUARANTEED:



- -------------------------

                                Page 37 of 46






                                  EXHIBIT 4

                     WARRANT PURCHASE AND SALE AGREEMENT


                  THIS WARRANT  PURCHASE AND SALE  AGREEMENT,  dated as of March
10, 1997, by and between GFL ADVANTAGE  FUND LIMITED,  a British  Virgin Islands
corporation  (the  "Seller"),  and  Clearwater  Fund IV LLC, a Delaware  limited
liability company (the "Buyer").

                             W I T N E S S E T H:

         WHEREAS,  the Seller is the beneficial  owner and registered  holder of
warrants (the "Warrants") to purchase  364,963 shares of Common Stock,  $.01 par
value (the "Common Stock"),  of Enzon, Inc., a Delaware  corporation  ("Enzon");
and

         WHEREAS,  subject to the terms and  conditions of this  Agreement,  the
Seller  desires to sell to the Buyer and the Buyer  desires to purchase from the
Seller, the Warrants;

         NOW,  THEREFORE,  in  consideration  of the  premises  and  the  mutual
covenants  contained  herein  and other  good and  valuable  consideration,  the
receipt and  sufficiency  of which are hereby  acknowledged,  the parties hereto
hereby agree as follows:


                                ARTICLE XIII.

                             Purchase and Sale of
                           Warrants; Purchase Price

                  A.  Sale  of  Warrants.  On  the  terms  and  subject  to  the
conditions  herein set forth,  the Buyer  shall  purchase  and pay for,  and the
Seller  shall  sell,  assign and  transfer  to the Buyer,  Warrants  to purchase
364,963  shares of Common  Stock.  The  shares of  Common  Stock  issuable  upon
exercise of the Warrants  are  referred to herein as the  "Warrant  Shares." The
Seller and the Buyer agree that,  upon  transfer of the Warrants to be purchased
by the Buyer  pursuant  hereto,  the Seller shall,  without  further act,  sell,
assign and  transfer to the Buyer all of the  Seller's  rights  relating to such
Warrants under the Registration Rights Agreement,  dated as of January 31, 1996,
by and between Enzon and the Seller (the "Registration Rights Agreement").

                  B.  Purchase Price.  The total purchase price to be paid by 
the Buyer for the Warrants to be purchased by the Buyer (the "Purchase Price")
shall be Two Hundred Eighteen Thousand Nine Hundred Seventy Seven and eighty one
hundredths Dollars ($218,977.80).

                  C.  Closing Payment.  The Buyer shall pay the Purchase Price 
by delivering good funds in United States Dollars to the escrow agent (the

"Escrow Agent") identified in the Joint Escrow

                                Page 38 of 46




Instructions attached hereto as Annex I (the "Joint Escrow Instructions"):


                  Citibank, N.A.
                  153 East 53rd Street
                  New York, New York
                  ABA No. 021000089

                  For credit to the account of Brian W. Pusch
                     Attorney Escrow Account
                  Account No. 3717 9446

Such delivery of funds shall be made against delivery by the Seller to the Buyer
of the Warrants at the Closing (as defined herein).  Promptly  following payment
by the Buyer to the Escrow Agent of an amount equal to the Purchase  Price,  but
in no event later than the Closing Date,  the Seller shall deliver to the Escrow
Agent the Warrants,  duly endorsed in blank or with a power affixed thereto,  in
proper form for  transfer,  accompanied  by all  requisite  securities  transfer
stamps.  By signing this Agreement,  the Buyer and the Seller each agrees to all
of the terms and  conditions  of,  and  becomes  a party  to,  the Joint  Escrow
Instructions,  all of the  provisions of which are  incorporated  herein by this
reference as if set forth in full.


                                 ARTICLE XIV.

                   Representations and Warranties of Seller

                  The Seller represents and warrants to the Buyer as follows:

                  A. Title to Warrants. The Seller has good and marketable title
to the  Warrants,  free  and  clear  of any and  all  liens,  pledges,  charges,
encumbrances,  and claims and rights of others of any nature whatsoever, and, if
the Buyer is without  notice of any adverse  claim with respect to the Warrants,
upon  consummation  of the  transactions  contemplated  hereby,  the Buyer  will
acquire good and marketable title to the Warrants, free and clear of any and all
liens, pledges,  charges,  encumbrances,  and claims and rights of others of any
nature whatsoever other than the restrictions referred to in Section 3.4 of this
Agreement.

                  B.  Organization  and  Corporate  Authority.  The  Seller is a
corporation duly organized, validly existing and in good standing under the laws
of the British  Virgin Islands and has the corporate  power to execute,  deliver
and perform this  Agreement  and to  consummate  the  transactions  contemplated
hereby on the part of the Seller.

                  C.  Authorization and Binding Effect.  The execution,

delivery and performance of this Agreement by the Seller, and the
consummation of the transactions contemplated hereby on the part

                                Page 39 of 46




of the Seller,  will have been duly authorized by all necessary corporate action
on the  part of the  Seller  on or  before  the  Closing  Date.  Subject  to the
immediately  preceding  sentence,  this  Agreement  has been duly  executed  and
delivered by the Seller and constitutes the legal,  valid and binding obligation
of the  Seller,  enforceable  in  accordance  with its  terms,  except as may be
limited by  applicable  bankruptcy,  reorganization,  insolvency,  moratorium or
similar laws relating to or affecting  generally the  enforcement  of creditors'
rights  and  except as the  availability  of  particular  remedies  of  specific
performance  may be limited under  generally  applicable  rules of law,  whether
enforcement is sought at law or in equity.

                  D.  Agreement  Not in  Violation  of Law or Other  Agreements.
Subject to the first sentence of Section 2.3 hereof, the execution, delivery and
performance  of  this  Agreement  by the  Seller,  and the  consummation  of the
transactions  contemplated  hereby on the part of the Seller, (a) do not violate
any material order, decree,  judgment or award to which the Seller or any of its
properties  is  subject;  and (b) do not and will not  result in a breach of, or
constitute a default under, or constitute an event which with notice or lapse of
time or both would  become a default  under,  the  Articles  of  Association  or
Memorandum of Association of the Seller or any indenture, loan agreement, credit
facility,  material lease, or other material agreement or material instrument to
which the Seller is a party or by which the Seller or any of its  properties  is
bound.  Subject to the first sentence of Section 2.3 hereof,  no  authorization,
approval  or consent  of, or notice to or filing  with,  any party is or will be
required for the  execution,  delivery or  performance  of this Agreement by the
Seller  or the  consummation  by the  Seller  of the  transactions  on its  part
contemplated hereby.


                                 ARTICLE XV.

                   Representations and Warranties of Buyer

                  The Buyer represents and warrants to the Seller as follows:

                  A.  Organization  and  Corporate  Authority.  The  Buyer  is a
limited liability company duly organized,  validly existing and in good standing
under the laws of the State of Delaware, and has the corporate power to execute,
deliver  and  perform  this  Agreement  and  to  consummate   the   transactions
contemplated hereby on the part of the Buyer.

                  B.  Authorization and Binding Effect. The execution, 
delivery and performance of this Agreement, and the consummation of the
transactions contemplated hereby on the part of the Buyer, have been duly
authorized by all necessary corporate action on the part of the Buyer.  This
Agreement has been duly executed and delivered by the Buyer, and this Agreement

constitutes the legal, valid and binding obligation of the Buyer, enforceable in

                                Page 40 of 46





accordance  with its terms,  except as may be limited by applicable  bankruptcy,
reorganization,  insolvency, moratorium or similar laws relating to or affecting
generally the enforcement of creditors' rights and except as the availability of
particular  remedies  of specific  performance  may be limited  under  generally
applicable rules of law, whether enforcement is sought at law or in equity.

                  C. No Violation  of Law or Other  Agreements.  The  execution,
delivery  and  performance  of  this  Agreement  and  the  consummation  of  the
transactions contemplated hereby and thereby on the part of the Buyer (a) do not
violate any material  provision of applicable  law or regulation or any material
order, decree,  judgment or award to which the Buyer or any of its properties is
subject;  and (b) do not and will not  result in a breach  of, or  constitute  a
default  under,  or constitute  an event which,  with notice or lapse of time or
both,  would  become a default  under,  the  [Certificate  of  Incorporation  or
By-Laws]  of the  Buyer  or any  indenture,  loan  agreement,  credit  facility,
material lease or other material  agreement or material  instrument to which the
Buyer is a party or by which the  Buyer or any of its  properties  is bound.  No
authorization, approval or consent of, or notice to or filing with, any party is
or will be required for the execution, delivery or performance of this Agreement
by the Buyer or the  consummation  of the  transactions  contemplated  hereby or
thereby by the Buyer.

                  D. Purchase for Investment. The Warrants to be acquired by the
Buyer as provided in this  Agreement are being acquired by the Buyer for its own
account for  investment  and not with a view to their public  distribution;  the
Buyer is an  accredited  investor (as that term is defined in Rule  501(a)(3) of
Regulation D under the Securities Act of 1933, as amended (the "1933 Act")); the
Buyer will not distribute  any of the Warrants in violation of applicable  state
securities  or  "blue  sky"  laws or the 1933 Act or the  applicable  rules  and
regulations of the SEC thereunder;  the Buyer  understands that the Warrants are
being  offered  and  sold to it in  reliance  on  specific  exemptions  from the
registration  requirements  of the United  States  federal and State  securities
laws; the Buyer has been furnished with all materials  relating to the business,
finances and  operations  of Enzon which have been  requested by the Buyer;  the
Buyer  understands  that no United  States  federal or state agency or any other
government or governmental  agencies has passed on or made any recommendation or
endorsement of the Warrants;  and the Buyer has had an opportunity to obtain and
to review Enzon's  Prospectus,  dated May 7, 1996, and the documents and reports
incorporated therein by reference.

                                 ARTICLE XVI.

                                   Closing

                  The  closing  hereunder  (the  "Closing")  shall take place at
10:00 a.m., New York City time, at the offices of the Escrow


                                Page 41 of 46




Agent on the date which is one  business day after the date the Buyer shall have
deposited an amount equal to the Purchase Price with the Escrow Agent.  The date
of the Closing is referred to in this Agreement as the "Closing Date".


                                ARTICLE XVII.

                              Certain Covenants

                  A.  Best Efforts.  The Buyer and the Seller shall use
their best efforts to cause the respective conditions to their obligations to
close the transaction contemplated hereby to be satisfied on or before the
Closing Date.  The Seller and the Buyer agree to furnish a copy of this
Agreement to Enzon promptly after the Closing.

                  B.  Covenants  with Enzon.  The Buyer  agrees with Enzon that,
upon transfer to the Buyer of the Warrants to be purchased by the Buyer pursuant
hereto,  the Buyer shall be bound by all of the  provisions of the  Registration
Rights  Agreement.  For  purposes  of  Section  9  of  the  Registration  Rights
Agreement,  the name and  address of the Buyer are as set forth in  Section  8.7
hereof and the Warrants which the Buyer is acquiring are as set forth herein.


                                ARTICLE XVIII.

                Conditions Precedent to Obligations of Seller

                  The  obligations  of the  Seller to sell the  Warrants  to the
Buyer under this  Agreement  are subject to the  satisfaction  of the  following
conditions at or before the Closing:

                  A.  Payments.  The Escrow Agent shall have received the
Purchase Price payable by the Buyer.

                  B.  Buyer's Performance.  All of the covenants and agreements 
to be complied with and performed by the Buyer on or before the Closing Date
shall have been complied with and performed in all material respects.

                  C.  Correctness of Buyer's Representations.  All
representations and warranties of the Buyer contained in this Agreement shall be
true and correct in all material respects on and as of the Closing Date with the
same force and effect as if such representations and warranties had been made on
and as of the Closing Date.

                  D.  Certain Consents.  Enzon shall have consented to
the transfer of the Warrants and assignment of rights under the Registration 
Rights Agreement.



                                Page 42 of 46




                                 ARTICLE XIX.

                 Conditions Precedent to Obligations of Buyer

                  The  obligations  of the Buyer to purchase the Warrants  under
this Agreement are subject to the satisfaction of the following conditions at or
before the Closing:

                  A.  Seller's Performance.  All of the covenants and
agreements to be complied with and performed by the Seller on or before the
Closing Date shall have been complied with and performed in all material
respects.

                  B.  Correctness of Seller's Representations.  All
representations and warranties of the Seller contained in this Agreement shall 
be true and correct in all material respects on and as of the Closing Date with
the same force and effect as if such representations and warranties had been
made on and as of the Closing Date.

                  C.  Certain Consents.  Enzon shall have consented to the 
transfer of the Warrants and assignment of rights under the Registration Rights
Agreement.

                  D.  Delivery of Certain Documents by Seller. (i) The Seller 
shall have delivered to the Escrow Agent the Warrants, duly endorsed in blank or
with stock powers affixed thereto, in proper form for transfer, accompanied by
all requisite securities transfer stamps; and

                  (ii) Enzon  shall have  received an opinion of the Law Offices
of Brian W. Pusch  meeting the  requirements  of Section 2(f) of the  Securities
Purchase  Agreement,  dated as of January 31, 1996, by and between Enzon and the
Seller,  reasonably  satisfactory in form,  scope and substance to Enzon, in the
form attached hereto as Annex II.


                                 ARTICLE XX.

                                   General

                  A.  Entire Agreement.  This Agreement contains the entire 
agreement between the parties hereto with respect to the subject matter hereof. 
There are no agreements which are not set forth herein.  This Agreement may not
be amended or revised except by a writing signed by the party to be charged with
enforcement.

                  B. Binding  Effect.  This Agreement  shall be binding upon and
inure to the benefit of the parties hereto and their  respective  successors and
permitted  assigns and, in the case of Section 5.2,  Enzon;  provided,  however,

this Agreement and all rights  hereunder may not be assigned by any party hereto
without the prior written consent of the other parties hereto.

                                Page 43 of 46




                  C.  Separate Counterparts.  This Agreement may be executed 
in counterparts, each of which when so executed shall constitute an original and
all of which when taken together shall constitute but one instrument.

                  D.  Transaction Costs.  Each party to this Agreement shall 
be responsible for its own costs attendant to the transactions  contemplated by
this Agreement, whether or not the Closing occurs.

                  E. Cumulative Remedies.  The remedies of the parties hereunder
shall be cumulative, and the exercise by the Buyer of any of its remedies at law
or in equity to recover any damages shall not affect any other remedy  available
to the Buyer and the  exercise by the Seller of any of its remedies at law or in
equity to recover any damages shall not affect any other remedy available to the
Seller.

                  F.  Survival of Representations and Warranties. The 
respective representations and warranties of the Seller and the Buyer set forth
in this Agreement shall survive the Closing notwithstanding any investigation
made by or on behalf of any such party.

                  G.  Notices.  Except as otherwise expressly provided herein, 
all notices hereunder, to be effective, shall be in writing and shall be mailed
by certified mail, postage and fees prepaid, or delivered personally or by
telephone line facsimile transmission to the party to be notified as follows:

                  (i)      If to the Seller:

                           c/o CITCO
                           Kaya Flamboyan 9
                           Curacao, Netherlands Antilles

                           Facsimile No. 011-599-932-2008

                           with a copy to:

                           Genesee International, Inc.
                           10500 N.E. 8th Street
                           Suite 1920
                           Bellevue, Washington 98004

                           Facsimile No. 206-462-4645

                  (ii)     If to the Buyer:

                           611 Druid Road East
                           Suite 200

                           Clearwater, Florida 34616
 
                           Facsimile No. 813-443-0143


                                Page 44 of 46





and shall be effective, in the case of mailing, four days after deposit with the
United States Postal Service and, in all other cases, on receipt.

                  A party may  change the  address to which such  communications
are to be directed to it by giving written notice to the other parties hereto of
such change in the manner above provided.

                  H.  Severability.  The provisions of this Agreement are
severable, and the invalidity of any provision shall not affect the validity 
of any other provision.

                  I. No Waiver.  The  failure of a party at any time or times to
require  performance of any provision  hereof shall not in any manner affect its
right  at a later  time  to  enforce  the  same.  No  waiver  by a party  of any
condition, or of the breach of any term, covenant,  representation,  warranty or
agreement contained in this Agreement,  whether by conduct or otherwise,  in any
one or more  instances  shall be  deemed  to be or  construed  as a  further  or
continuing  waiver  of any such  condition  or  breach  or a waiver of any other
condition or of the breach of any other term, covenant, representation, warranty
or agreement contained in this Agreement.

                  J.  Brokers,  Finders,  Etc.  Each of the Buyer and the Seller
represents  and warrants to the other that it has not retained or dealt with any
person as broker, finder or otherwise (each, a "Claimant" and collectively,  the
"Claimants")  as would entitle any such person to any fee or other  compensation
in connection with the  transactions  contemplated by this Agreement and each of
the Buyer and the Seller agrees to indemnify and hold harmless the other against
any claim,  cost or liability from any Claimant claiming by or through the party
giving such indemnity.

                  K.  Governing Law.  This Agreement shall be governed by and 
construed in accordance with the laws of the State of New York.

                  L.  Headings.  The Article and Section headings and captions 
contained in this Agreement are for convenience only and shall not affect the
interpretation of this Agreement.



                                Page 45 of 46





                  IN WITNESS WHEREOF,  the Buyer and the Seller have caused this
Agreement to be duly executed by their respective  officers as of the date first
above written.

                                  GFL ADVANTAGE FUND LIMITED



                                  By   /s/ A.P. de Groot
                                    ------------------------------ 
                                    Name:   A.P. de Groot
                                    Title:  President


                                  CLEARWATER FUND IV LLC



                                  By   /s/ Hans F. Heye
                                    ------------------------------
                                    Name:   Hans F. Heye
                                    Title:  Managing Member



                                Page 46 of 46