FORM 5 
                                   U.S. SECURITIES AND EXCHANGE COMMISSION
                                           WASHINGTON, D.C. 20549
                         ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP
Check this box if 
no longer subject to 
Section 16. Form 4             Filed pursuant to Section 16(a) of the
or Form 5 obligations    Securities Act of 1934, Section 17(a) of the Public 
may continue.               Utility Holding Company Act of 1935 or Section 
                             30(f) of the Investment Company Act of 1940
SEE Instruction 1(b).
Form 3 Holdings Reported
Form 4 Transactions Reported
1. Name and Address of Reporting Person 2. Issuer Name and Ticker or Trading Symbol 6. Relationship of Reporting Person to Issuer ENZON, INC. (ENZN) (Check all applicable) CARUSO JOHN A. (Last) (First) (Middle) 3. IRS or Social 4. Statement for __ Director ______ 10% Owner Security Number of Month/Year X Officer __ Other 5 FRANKLIN ROAD Reporting Person JUNE 30, 1995 (specify below) (Voluntary) Vice President, Business Development, General Counsel and Secretary (Street) 5. If Amendment, Date of Original (Month/Year) MENDHAM NJ 07945 (City) (State) (Zip) TABLE I - NON-DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED 1. Title of Security 2. Trans- 3. Trans- 4. Securities Acquired 5. Amount of 6. Owner- 7. Nature of (Instr. 3) action action (A) or Disposed of Securities ship Indirect Date Code (D) Beneficially Form: Beneficial (Month/ (Instr. (Instr. 3, 4 and 5) Owned at End (D) or Ownership Day/ 8) of Issuer's Indirect (Instr. Year) Fiscal Year (I) 4) (Instr. 3 (Instr. and 4) 4) Amount (A) or Price (D)
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. (Over) FORM 5 (CONTINUED) TABLE II - DERIVATIVE SECURITIES ACQUIRED, DISPOSED OF, OR BENEFICIALLY OWNED 1. Title of Derivative 2.Conver3.Trans-4.Transac-5.Number of6.Date 7.Title and Amount of 8.Price9.Number10. 11. Na- ture Security sion action tion Deriv- ExercisableUnder-lying of of Owner- of In- (Instru. 3 ) or Date Code ative and Securities (Instr. 3 Deriv-Deriv- ship direct Exercise(Month/Day/(Instr.SecuritiesExpirationand 4) ative ative of De- Bene- Price Year)8) Ac- Date Secur-Secur- ficial of quired (A) (Month/Day/ ity ities rivative Own- Deriv- or Disposed Year) (Instr.Bene- ership ative of (D) 5) ficially Security:(Instr. 4) Security (Instr. 3, Owned (D) 4, and 5) at or In- End of Direct Year (Instr. (I)(Instr. 4) 4) (A) (D) Date Expira- Title Amount Exer- tion or cisableDate Number of Shares STOCK OPTION (RIGHT TO $2.09 1/20/95A 40,000 1/20/971/20/05COMMON STOCK 40,000 $2.09 40,000 D -- PURCHASE)+ STOCK OPTION (RIGHT TO $2.63 8/24/94A 42,000 8/24/968/24/04Common Stock 42,000 $2.63 42,000 D -- PURCHASE)+ Explanation of Responses: + Granted under the Company's Non-Qualified Stock Option Plan, as amended, a Rule 16b-3 plan. ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations . /S/JOHN A. CARUSO 2/23/96 SEE 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). **Signature of Reporting Person Date Note: File three copies of this Form, one of which must be manually signed. If space provided is insufficient, SEE Instruction 6 for procedure.